SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hjg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 3hjg PUTATIVE
ALPHA-RIBAZOLE-5'-PH
OSPHATE PHOSPHATASE
COBC
(Vibrio
parahaemolyticus) 		4 / 8 LEU A  20
SER A 170
GLN A 107
ASP A 103
 None
 1.14A 1ig3A-3hjgA:
undetectable
1ig3B-3hjgA:
undetectable		 1ig3A-3hjgA:
20.96
1ig3B-3hjgA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 3hjg PUTATIVE
ALPHA-RIBAZOLE-5'-PH
OSPHATE PHOSPHATASE
COBC
(Vibrio
parahaemolyticus) 		3 / 3 ALA A 156
VAL A 158
TRP A 131
 None
 0.86A 1w5uC-3hjgA:
undetectable
1w5uD-3hjgA:
undetectable		 1w5uC-3hjgA:
8.51
1w5uD-3hjgA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 3hjg PUTATIVE
ALPHA-RIBAZOLE-5'-PH
OSPHATE PHOSPHATASE
COBC
(Vibrio
parahaemolyticus) 		4 / 8 GLY A 175
THR A 146
ILE A 174
SER A 178
 None
 1.05A 2a8tB-3hjgA:
undetectable		 2a8tB-3hjgA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 3hjg PUTATIVE
ALPHA-RIBAZOLE-5'-PH
OSPHATE PHOSPHATASE
COBC
(Vibrio
parahaemolyticus) 		4 / 7 ARG A  10
GLY A 148
SER A 178
ARG A 152
 SO4  A 212 (-3.4A)
SO4  A 212 (-4.2A)
None
None
 1.09A 2c8aB-3hjgA:
undetectable		 2c8aB-3hjgA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 3hjg PUTATIVE
ALPHA-RIBAZOLE-5'-PH
OSPHATE PHOSPHATASE
COBC
(Vibrio
parahaemolyticus) 		3 / 3 TRP A 131
ALA A 156
VAL A 158
 None
 0.72A 2izqA-3hjgA:
undetectable
2izqB-3hjgA:
undetectable		 2izqA-3hjgA:
8.51
2izqB-3hjgA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 3hjg PUTATIVE
ALPHA-RIBAZOLE-5'-PH
OSPHATE PHOSPHATASE
COBC
(Vibrio
parahaemolyticus) 		4 / 7 VAL A  47
ILE A   6
TYR A   7
ILE A 144
 None
 0.97A 3hgxA-3hjgA:
undetectable		 3hgxA-3hjgA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3hjg PUTATIVE
ALPHA-RIBAZOLE-5'-PH
OSPHATE PHOSPHATASE
COBC
(Vibrio
parahaemolyticus) 		3 / 3 ALA A 156
VAL A 158
TRP A 131
 None
 0.71A 3l8lA-3hjgA:
undetectable
3l8lB-3hjgA:
undetectable		 3l8lA-3hjgA:
8.51
3l8lB-3hjgA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 3hjg PUTATIVE
ALPHA-RIBAZOLE-5'-PH
OSPHATE PHOSPHATASE
COBC
(Vibrio
parahaemolyticus) 		3 / 3 ALA A 156
VAL A 158
TRP A 131
 None
 0.84A 3l8lC-3hjgA:
undetectable
3l8lD-3hjgA:
undetectable		 3l8lC-3hjgA:
8.51
3l8lD-3hjgA:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 3hjg PUTATIVE
ALPHA-RIBAZOLE-5'-PH
OSPHATE PHOSPHATASE
COBC
(Vibrio
parahaemolyticus) 		4 / 6 ARG A 126
GLN A  23
PRO A  54
LEU A  79
 None
 1.41A 3tgvB-3hjgA:
undetectable		 3tgvB-3hjgA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 3hjg PUTATIVE
ALPHA-RIBAZOLE-5'-PH
OSPHATE PHOSPHATASE
COBC
(Vibrio
parahaemolyticus) 		5 / 10 ILE A 135
ILE A 154
HIS A 181
LEU A   8
ILE A 182
 None
 1.30A 4dtaA-3hjgA:
undetectable		 4dtaA-3hjgA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_B_MTXB604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3hjg PUTATIVE
ALPHA-RIBAZOLE-5'-PH
OSPHATE PHOSPHATASE
COBC
(Vibrio
parahaemolyticus) 		5 / 12 VAL A 179
ALA A 177
LEU A  61
LYS A  41
ILE A  50
 None
 1.18A 4q0dB-3hjgA:
undetectable		 4q0dB-3hjgA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0D_E_MTXE604_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3hjg PUTATIVE
ALPHA-RIBAZOLE-5'-PH
OSPHATE PHOSPHATASE
COBC
(Vibrio
parahaemolyticus) 		5 / 12 VAL A 179
ALA A 177
LEU A  61
LYS A  41
ILE A  50
 None
 1.18A 4q0dE-3hjgA:
undetectable		 4q0dE-3hjgA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 3hjg PUTATIVE
ALPHA-RIBAZOLE-5'-PH
OSPHATE PHOSPHATASE
COBC
(Vibrio
parahaemolyticus) 		4 / 7 ASN A 176
VAL A  14
ALA A  16
GLY A  19
 None
 0.89A 5fpdB-3hjgA:
undetectable		 5fpdB-3hjgA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3hjg PUTATIVE
ALPHA-RIBAZOLE-5'-PH
OSPHATE PHOSPHATASE
COBC
(Vibrio
parahaemolyticus) 		5 / 10 ILE A 138
ASN A 136
ILE A 144
ILE A 151
LEU A 155
 None
 1.40A 5vkqA-3hjgA:
undetectable
5vkqB-3hjgA:
undetectable		 5vkqA-3hjgA:
7.97
5vkqB-3hjgA:
7.97