SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hjh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA2001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		4 / 6 TRP A 321
TRP A  73
GLY A 256
PRO A 254
 None
 1.36A 1dedA-3hjhA:
undetectable		 1dedA-3hjhA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		4 / 7 PHE A 264
PHE A 122
LEU A  92
PHE A 265
 None
 0.96A 1wrlE-3hjhA:
undetectable		 1wrlE-3hjhA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		5 / 12 HIS A 120
TYR A 275
LEU A 272
VAL A 108
LEU A 212
 None
 1.45A 2prgB-3hjhA:
undetectable		 2prgB-3hjhA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		3 / 3 LEU A 212
PRO A 213
ARG A  91
 None
 0.66A 2qd4B-3hjhA:
undetectable		 2qd4B-3hjhA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		5 / 12 LEU A 450
LEU A 449
LEU A 361
LEU A 378
LEU A 401
 None
 1.30A 3d90B-3hjhA:
undetectable		 3d90B-3hjhA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		3 / 3 GLU A 216
VAL A 117
CYH A 118
 None
 1.08A 3fbxA-3hjhA:
undetectable		 3fbxA-3hjhA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		4 / 5 PRO A 213
ILE A 257
TRP A  73
PHE A 122
 None
 1.24A 3topB-3hjhA:
undetectable		 3topB-3hjhA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		5 / 12 LEU A 339
LEU A  22
GLN A 356
VAL A 438
THR A  29
 None
 1.33A 3zqtA-3hjhA:
undetectable		 3zqtA-3hjhA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		3 / 3 LEU A  30
ILE A  34
ARG A  37
 None
 0.65A 4mk4B-3hjhA:
2.4		 4mk4B-3hjhA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		4 / 7 GLU A 207
ILE A 189
LEU A 145
ILE A 209
 None
 0.98A 4xumA-3hjhA:
undetectable		 4xumA-3hjhA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		4 / 7 ILE A  88
HIS A 215
LEU A  92
GLY A 160
 None
 1.02A 4z69A-3hjhA:
undetectable		 4z69A-3hjhA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		4 / 6 LEU A 272
LEU A 327
PHE A 276
LEU A 282
 None
 1.00A 5gs4A-3hjhA:
undetectable		 5gs4A-3hjhA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		5 / 7 VAL A 385
ILE A 444
VAL A 435
PRO A 359
ALA A 442
 None
 1.23A 5ospA-3hjhA:
undetectable		 5ospA-3hjhA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		5 / 12 GLY A 433
GLY A  24
ALA A  26
ILE A 444
LEU A 358
 None
 1.13A 6b3aA-3hjhA:
undetectable		 6b3aA-3hjhA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		5 / 12 GLY A 433
GLY A  24
ALA A  26
ILE A 444
LEU A 358
 None
 1.09A 6b3bA-3hjhA:
undetectable		 6b3bA-3hjhA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 3hjh TRANSCRIPTION-REPAIR
-COUPLING FACTOR
(Escherichia
coli) 		5 / 12 GLU A 431
LEU A 441
ALA A  25
PHE A  62
LEU A 415
 None
 1.10A 6ew0G-3hjhA:
undetectable		 6ew0G-3hjhA:
9.64