SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hjp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 7 THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.45A 2v2gA-3hjpA:
21.1
2v2gB-3hjpA:
21.0		 2v2gA-3hjpA:
26.81
2v2gB-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 7 THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.47A 2v2gA-3hjpA:
21.1
2v2gB-3hjpA:
21.0		 2v2gA-3hjpA:
26.81
2v2gB-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 7 THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.46A 2v2gC-3hjpA:
21.1
2v2gD-3hjpA:
21.1		 2v2gC-3hjpA:
26.81
2v2gD-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 7 THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.45A 2v2gC-3hjpA:
21.1
2v2gD-3hjpA:
21.1		 2v2gC-3hjpA:
26.81
2v2gD-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_A_BEZA1222_0
(PEROXIREDOXIN 6)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 8 THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.39A 2v32A-3hjpA:
21.0
2v32B-3hjpA:
21.0		 2v32A-3hjpA:
26.81
2v32B-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_B_BEZB1220_0
(PEROXIREDOXIN 6)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 8 THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.47A 2v32A-3hjpA:
21.0
2v32B-3hjpA:
21.0		 2v32A-3hjpA:
26.81
2v32B-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		5 / 8 PRO A  38
THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 ( 4.2A)
CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.44A 2v32C-3hjpA:
21.1
2v32D-3hjpA:
23.2		 2v32C-3hjpA:
26.81
2v32D-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 8 THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.47A 2v32C-3hjpA:
21.1
2v32D-3hjpA:
23.2		 2v32C-3hjpA:
26.81
2v32D-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_A_BEZA1222_0
(PEROXIREDOXIN 6.)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		5 / 9 PRO A  38
THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 ( 4.2A)
CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.46A 2v41A-3hjpA:
21.0
2v41B-3hjpA:
21.1		 2v41A-3hjpA:
26.81
2v41B-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_B_BEZB1222_0
(PEROXIREDOXIN 6.)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		5 / 9 PRO A  38
THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 ( 4.2A)
CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.54A 2v41A-3hjpA:
21.0
2v41B-3hjpA:
21.1		 2v41A-3hjpA:
26.81
2v41B-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		5 / 8 PRO A  38
THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 ( 4.2A)
CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.54A 2v41C-3hjpA:
23.1
2v41D-3hjpA:
23.2		 2v41C-3hjpA:
26.81
2v41D-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		5 / 8 PRO A  38
THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 ( 4.2A)
CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.47A 2v41C-3hjpA:
23.1
2v41D-3hjpA:
23.2		 2v41C-3hjpA:
26.81
2v41D-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 7 THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.53A 2v41E-3hjpA:
20.8
2v41F-3hjpA:
20.8		 2v41E-3hjpA:
26.81
2v41F-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 7 THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.49A 2v41E-3hjpA:
20.8
2v41F-3hjpA:
20.8		 2v41E-3hjpA:
26.81
2v41F-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 8 THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.50A 2v41G-3hjpA:
20.8
2v41H-3hjpA:
20.9		 2v41G-3hjpA:
26.81
2v41H-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		5 / 8 PRO A  38
THR A  42
VAL A  44
SER A  45
ARG A 119
 CL  A 700 ( 4.2A)
CL  A 700 (-3.2A)
None
CL  A 700 (-3.0A)
CL  A 700 (-3.5A)
 0.49A 2v41G-3hjpA:
20.8
2v41H-3hjpA:
20.9		 2v41G-3hjpA:
26.81
2v41H-3hjpA:
26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 8 VAL A   2
VAL A 135
ILE A  11
GLY A 103
 None
 0.90A 3hjoB-3hjpA:
undetectable		 3hjoB-3hjpA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_E_NIOE5660_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		3 / 3 GLU A 142
GLU A  48
TRP A 134
 None
 1.35A 3hrdA-3hjpA:
undetectable
3hrdE-3hjpA:
undetectable
3hrdF-3hjpA:
undetectable		 3hrdA-3hjpA:
18.12
3hrdE-3hjpA:
18.12
3hrdF-3hjpA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		5 / 12 LEU A 108
PRO A 143
GLY A  68
ALA A  39
ILE A  90
 None
None
None
CL  A 700 ( 4.6A)
None
 0.96A 3ku1A-3hjpA:
undetectable		 3ku1A-3hjpA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		5 / 12 LEU A 108
PRO A 143
GLY A  68
ALA A  39
ILE A  90
 None
None
None
CL  A 700 ( 4.6A)
None
 0.95A 3ku1C-3hjpA:
undetectable		 3ku1C-3hjpA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 8 ALA A 101
ASP A  26
ILE A  23
ILE A  67
 None
 0.89A 4kttD-3hjpA:
undetectable		 4kttD-3hjpA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 6 LEU A 108
ASP A  72
VAL A 104
ALA A 105
 None
 0.97A 4nkxA-3hjpA:
undetectable		 4nkxA-3hjpA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RMJ_A_NCAA402_0
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-2)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 7 ILE A  67
PHE A  36
LEU A  13
ILE A  11
 None
 0.84A 4rmjA-3hjpA:
undetectable		 4rmjA-3hjpA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 6 PHE A 122
GLY A 103
TYR A 102
ALA A 101
 None
 1.26A 4yshB-3hjpA:
undetectable		 4yshB-3hjpA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5H_C_ACTC1742_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SUBUNIT)		 3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)
(Sulfolobus
solfataricus) 		4 / 5 ASP A  17
LYS A  19
THR A  89
ASP A  15
 None
 1.25A 5g5hC-3hjpA:
0.0		 5g5hC-3hjpA:
12.81