SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hjv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		4 / 8 GLN A  68
LEU A  72
LEU A  49
TYR A  47
 CL  A 331 ( 4.2A)
None
None
CXS  A 325 (-4.2A)
 1.16A 1hk2A-3hjvA:
undetectable		 1hk2A-3hjvA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		5 / 12 TYR A 101
GLY A 108
ILE A 248
LEU A 217
THR A 220
 None
 1.02A 1p91B-3hjvA:
undetectable		 1p91B-3hjvA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		3 / 3 ALA A  74
VAL A  76
TRP A  79
 None
 0.93A 1tkqB-3hjvA:
undetectable		 1tkqB-3hjvA:
4.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		4 / 6 ALA A 149
ILE A 174
VAL A 172
PHE A 166
 None
 0.96A 2cizA-3hjvA:
undetectable		 2cizA-3hjvA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		5 / 11 SER A 102
LEU A  49
PHE A  38
GLU A 279
LEU A  24
 None
 1.27A 2v0mA-3hjvA:
undetectable		 2v0mA-3hjvA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		5 / 11 SER A 102
LEU A  49
PHE A  38
GLU A 279
LEU A  24
 None
 1.23A 2v0mD-3hjvA:
undetectable		 2v0mD-3hjvA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		5 / 11 ALA A 151
ALA A 147
GLY A 192
GLY A 185
ILE A 174
 None
None
None
SO4  A 321 (-3.1A)
None
 1.16A 2x1lA-3hjvA:
undetectable		 2x1lA-3hjvA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		3 / 3 ASP A  26
LEU A  27
GLN A  84
 SO4  A 319 (-4.9A)
None
SO4  A 323 (-3.4A)
 0.81A 3g4lA-3hjvA:
undetectable		 3g4lA-3hjvA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		4 / 5 GLN A  16
LEU A  98
SER A  97
ASP A 215
 CL  A 331 ( 3.8A)
None
CL  A 331 (-2.9A)
None
 1.22A 4qtuD-3hjvA:
undetectable		 4qtuD-3hjvA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		4 / 7 GLY A  95
ALA A  94
VAL A 274
LEU A 277
 None
 0.78A 6dwnB-3hjvA:
undetectable		 6dwnB-3hjvA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		5 / 12 VAL A 105
LEU A  49
ALA A 115
GLN A  19
LEU A  98
 None
None
None
CL  A 328 (-3.5A)
None
 1.13A 6ew0B-3hjvA:
undetectable		 6ew0B-3hjvA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		5 / 12 VAL A 105
LEU A  49
ALA A 115
GLN A  19
LEU A  98
 None
None
None
CL  A 328 (-3.5A)
None
 1.13A 6ew0D-3hjvA:
undetectable		 6ew0D-3hjvA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		5 / 12 VAL A 105
LEU A  49
ALA A 115
GLN A  19
LEU A  98
 None
None
None
CL  A 328 (-3.5A)
None
 1.13A 6ew0F-3hjvA:
undetectable		 6ew0F-3hjvA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		5 / 12 VAL A 105
LEU A  49
ALA A 115
GLN A  19
LEU A  98
 None
None
None
CL  A 328 (-3.5A)
None
 1.13A 6ew0G-3hjvA:
undetectable		 6ew0G-3hjvA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		5 / 12 VAL A 105
LEU A  49
ALA A 115
GLN A  19
LEU A  98
 None
None
None
CL  A 328 (-3.5A)
None
 1.13A 6ew0H-3hjvA:
undetectable		 6ew0H-3hjvA:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE
(Vibrio
cholerae) 		5 / 12 VAL A 105
LEU A  49
ALA A 115
GLN A  19
LEU A  98
 None
None
None
CL  A 328 (-3.5A)
None
 1.13A 6ew0I-3hjvA:
undetectable		 6ew0I-3hjvA:
13.48