SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hk0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 3hk0 GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		5 / 11 THR A 265
VAL A 241
VAL A 254
ARG A 319
GLU A 243
 None
 1.09A 1t6zA-3hk0A:
undetectable		 1t6zA-3hk0A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3hk0 GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 7 LEU A 227
LEU A 223
GLU A 167
ARG A 337
 None
None
None
SCN  A  15 (-3.8A)
 0.98A 2jn3A-3hk0A:
undetectable		 2jn3A-3hk0A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3hk0 GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		3 / 3 ASN A 309
MET A 333
PHE A 287
 None
 0.74A 3g4lD-3hk0A:
undetectable		 3g4lD-3hk0A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJQ_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3hk0 GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		5 / 12 ASN A 285
MET A 208
ILE A 235
PHE A 204
GLU A 167
 None
 1.30A 4zjqD-3hk0A:
undetectable		 4zjqD-3hk0A:
12.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 3hk0 GROWTH FACTOR
RECEPTOR-BOUND
PROTEIN 10
(Homo
sapiens) 		4 / 8 LEU A 345
TYR A 341
GLU A 170
ASN A 285
 SCN  A  15 ( 4.8A)
None
None
None
 1.09A 6c71B-3hk0A:
undetectable		 6c71B-3hk0A:
13.15