SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hk4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.38A 1p6kA-3hk4A:
undetectable
1p6kB-3hk4A:
undetectable		 1p6kA-3hk4A:
15.26
1p6kB-3hk4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 MET A   1
VAL A 105
PHE A  78
GLU A   5
 None
 1.48A 3ufoA-3hk4A:
undetectable
3ufoB-3hk4A:
undetectable		 3ufoA-3hk4A:
15.26
3ufoB-3hk4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 MET A   1
VAL A 105
PHE A  78
GLU A   5
 None
 1.47A 3ufpA-3hk4A:
undetectable
3ufpB-3hk4A:
undetectable		 3ufpA-3hk4A:
15.26
3ufpB-3hk4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.47A 3ufpA-3hk4A:
undetectable
3ufpB-3hk4A:
undetectable		 3ufpA-3hk4A:
15.26
3ufpB-3hk4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.45A 3ufrA-3hk4A:
undetectable
3ufrB-3hk4A:
undetectable		 3ufrA-3hk4A:
15.26
3ufrB-3hk4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 MET A   1
VAL A 105
PHE A  78
GLU A   5
 None
 1.48A 3ufsA-3hk4A:
undetectable
3ufsB-3hk4A:
undetectable		 3ufsA-3hk4A:
15.26
3ufsB-3hk4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.45A 4cx6A-3hk4A:
undetectable
4cx6B-3hk4A:
undetectable		 4cx6A-3hk4A:
14.53
4cx6B-3hk4A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		3 / 3 ARG A  51
ASP A  18
ASP A   9
 None
 0.86A 4kicB-3hk4A:
undetectable		 4kicB-3hk4A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 MET A   1
VAL A 105
PHE A  78
GLU A   5
 None
 1.47A 5ad4A-3hk4A:
undetectable
5ad4B-3hk4A:
undetectable		 5ad4A-3hk4A:
15.26
5ad4B-3hk4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.44A 5ad4A-3hk4A:
undetectable
5ad4B-3hk4A:
undetectable		 5ad4A-3hk4A:
15.26
5ad4B-3hk4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.37A 5fvuA-3hk4A:
undetectable
5fvuB-3hk4A:
undetectable		 5fvuA-3hk4A:
15.16
5fvuB-3hk4A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.46A 5fvwA-3hk4A:
undetectable
5fvwB-3hk4A:
undetectable		 5fvwA-3hk4A:
15.16
5fvwB-3hk4A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.48A 5unyA-3hk4A:
undetectable
5unyB-3hk4A:
undetectable		 5unyA-3hk4A:
15.26
5unyB-3hk4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.48A 5uo0A-3hk4A:
undetectable
5uo0B-3hk4A:
undetectable		 5uo0A-3hk4A:
15.26
5uo0B-3hk4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.49A 5uo6A-3hk4A:
undetectable
5uo6B-3hk4A:
undetectable		 5uo6A-3hk4A:
15.16
5uo6B-3hk4A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.49A 5uo7A-3hk4A:
undetectable
5uo7B-3hk4A:
undetectable		 5uo7A-3hk4A:
15.16
5uo7B-3hk4A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.50A 5vukA-3hk4A:
undetectable
5vukB-3hk4A:
undetectable		 5vukA-3hk4A:
15.26
5vukB-3hk4A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.48A 5vuvA-3hk4A:
undetectable
5vuvB-3hk4A:
undetectable		 5vuvA-3hk4A:
15.16
5vuvB-3hk4A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 MET A   1
VAL A 105
PHE A  78
GLU A   5
 None
 1.45A 5vv3A-3hk4A:
undetectable
5vv3B-3hk4A:
undetectable		 5vv3A-3hk4A:
15.16
5vv3B-3hk4A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.46A 5vv3A-3hk4A:
undetectable
5vv3B-3hk4A:
undetectable		 5vv3A-3hk4A:
15.16
5vv3B-3hk4A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.44A 5vv5A-3hk4A:
undetectable
5vv5B-3hk4A:
undetectable		 5vv5A-3hk4A:
15.16
5vv5B-3hk4A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hk4 MLR7391 PROTEIN
(Mesorhizobium
loti) 		4 / 7 PHE A  78
GLU A   5
MET A   1
VAL A 105
 None
 1.46A 6av1A-3hk4A:
undetectable
6av1B-3hk4A:
undetectable		 6av1A-3hk4A:
15.44
6av1B-3hk4A:
15.44