SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hkm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3hkm OS03G0854200 PROTEIN
(Oryza
sativa) 		4 / 5 SER A 219
ARG A 221
LEU A 153
ASN A  12
 None
 1.06A 1y0xX-3hkmA:
undetectable		 1y0xX-3hkmA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 3hkm OS03G0854200 PROTEIN
(Oryza
sativa) 		4 / 5 VAL A 170
VAL A 139
GLN A  35
ARG A  15
 None
 1.34A 3bjwH-3hkmA:
undetectable		 3bjwH-3hkmA:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 3hkm OS03G0854200 PROTEIN
(Oryza
sativa) 		3 / 3 MET A 203
VAL A 151
GLU A 206
 None
 0.73A 3c6gA-3hkmA:
undetectable		 3c6gA-3hkmA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 3hkm OS03G0854200 PROTEIN
(Oryza
sativa) 		4 / 5 SER A 114
ARG A 214
GLY A 215
GLU A 213
 None
 1.27A 3k9fA-3hkmA:
undetectable
3k9fB-3hkmA:
undetectable
3k9fC-3hkmA:
undetectable		 3k9fA-3hkmA:
23.51
3k9fB-3hkmA:
23.51
3k9fC-3hkmA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKA_A_SAMA400_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE H)		 3hkm OS03G0854200 PROTEIN
(Oryza
sativa) 		5 / 12 THR A 199
GLY A 142
HIS A 168
ASP A 207
SER A 165
 None
 1.25A 3tkaA-3hkmA:
undetectable		 3tkaA-3hkmA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3hkm OS03G0854200 PROTEIN
(Oryza
sativa) 		4 / 7 LEU A  84
LEU A  88
ALA A 126
ALA A 119
 None
 0.66A 4z90F-3hkmA:
undetectable
4z90G-3hkmA:
undetectable
4z90H-3hkmA:
undetectable
4z90J-3hkmA:
undetectable		 4z90F-3hkmA:
21.08
4z90G-3hkmA:
21.08
4z90H-3hkmA:
21.08
4z90J-3hkmA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE0_A_XINA401_2
(AP2-ASSOCIATED
PROTEIN KINASE 1)		 3hkm OS03G0854200 PROTEIN
(Oryza
sativa) 		4 / 5 LEU A  84
VAL A  64
CYH A 124
CYH A  92
 None
 1.50A 5te0A-3hkmA:
undetectable		 5te0A-3hkmA:
21.02