SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hl1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		5 / 10 LEU A 279
ILE A 278
ALA A 270
LEU A 268
PHE A 275
 None
 1.17A 1xp0A-3hl1A:
undetectable		 1xp0A-3hl1A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		3 / 3 ASP A 132
ASP A 139
ASP A 135
 None
 0.58A 2igtA-3hl1A:
undetectable		 2igtA-3hl1A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		3 / 3 ASP A 132
ASP A 139
ASP A 135
 None
 0.60A 2igtB-3hl1A:
undetectable		 2igtB-3hl1A:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		5 / 10 TYR A 315
THR A  24
VAL A  31
VAL A  50
ILE A  25
 None
 1.45A 2qboA-3hl1A:
undetectable		 2qboA-3hl1A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		4 / 6 GLU A 121
TYR A  28
LYS A 229
PRO A 231
 UNL  A 317 (-2.7A)
None
None
None
 1.42A 2vmyA-3hl1A:
undetectable		 2vmyA-3hl1A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_A_SAMA501_0
(SPERMIDINE SYNTHASE)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		5 / 12 GLY A 141
ASP A 132
ASP A 148
GLY A 144
THR A 127
 None
None
None
UNL  A 317 ( 4.4A)
None
 0.90A 3bwcA-3hl1A:
undetectable		 3bwcA-3hl1A:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_D_486D2_2
(GLUCOCORTICOID
RECEPTOR)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		4 / 5 LEU A  73
ASN A 280
MET A 168
TYR A  69
 None
 1.45A 3h52D-3hl1A:
0.9		 3h52D-3hl1A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		4 / 5 GLU A 206
GLY A 205
TYR A 147
GLU A  21
 UNL  A 317 (-4.3A)
UNL  A 317 (-3.4A)
None
UNL  A 317 (-2.8A)
 1.33A 3w9tA-3hl1A:
undetectable		 3w9tA-3hl1A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		4 / 5 GLU A 206
GLY A 205
TYR A 147
GLU A  21
 UNL  A 317 (-4.3A)
UNL  A 317 (-3.4A)
None
UNL  A 317 (-2.8A)
 1.32A 3w9tC-3hl1A:
undetectable		 3w9tC-3hl1A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		4 / 5 GLU A 206
GLY A 205
TYR A 147
GLU A  21
 UNL  A 317 (-4.3A)
UNL  A 317 (-3.4A)
None
UNL  A 317 (-2.8A)
 1.33A 3w9tD-3hl1A:
undetectable		 3w9tD-3hl1A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		4 / 5 GLU A 206
GLY A 205
TYR A 147
GLU A  21
 UNL  A 317 (-4.3A)
UNL  A 317 (-3.4A)
None
UNL  A 317 (-2.8A)
 1.32A 3w9tG-3hl1A:
undetectable		 3w9tG-3hl1A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		4 / 6 LEU A  73
PHE A 283
LEU A 279
PHE A 275
 None
 1.05A 3wg7C-3hl1A:
5.8
3wg7J-3hl1A:
undetectable		 3wg7C-3hl1A:
21.45
3wg7J-3hl1A:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA601_1
(SERUM ALBUMIN)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		5 / 11 TYR A  27
VAL A 312
GLY A 251
THR A 253
SER A 103
 None
 1.36A 4or0A-3hl1A:
undetectable		 4or0A-3hl1A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS0_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		4 / 7 GLY A 205
GLN A 204
TYR A  28
HIS A  56
 UNL  A 317 (-3.4A)
None
None
UNL  A 317 (-4.2A)
 1.02A 4ws0A-3hl1A:
undetectable		 4ws0A-3hl1A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WS1_A_URFA301_1
(URACIL-DNA
GLYCOSYLASE)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		4 / 8 GLY A 205
GLN A 204
TYR A  28
HIS A  56
 UNL  A 317 (-3.4A)
None
None
UNL  A 317 (-4.2A)
 1.00A 4ws1A-3hl1A:
undetectable		 4ws1A-3hl1A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		4 / 4 VAL A 161
ALA A  66
ASN A  65
GLN A 167
 None
 1.20A 4zgfA-3hl1A:
undetectable		 4zgfA-3hl1A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		4 / 4 LEU A 268
ILE A 303
PRO A  26
LEU A 106
 None
 1.17A 5eb3A-3hl1A:
undetectable		 5eb3A-3hl1A:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PAH_A_LDPA600_1
(PHENYLALANINE
4-MONOOXYGENASE)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		4 / 4 HIS A  56
HIS A 232
TYR A  28
GLU A  53
 UNL  A 317 (-4.2A)
UNL  A 317 (-4.3A)
None
UNL  A 317 (-3.1A)
 1.41A 5pahA-3hl1A:
undetectable		 5pahA-3hl1A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		5 / 12 VAL A 183
LEU A  10
LEU A   7
ALA A 194
GLN A  15
 None
 0.87A 6ew0B-3hl1A:
undetectable		 6ew0B-3hl1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		5 / 12 VAL A 183
LEU A  10
LEU A   7
ALA A 194
GLN A  15
 None
 0.87A 6ew0D-3hl1A:
undetectable		 6ew0D-3hl1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_1
(TUBULIN BETA CHAIN)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		5 / 12 VAL A 183
LEU A  10
ALA A 194
LEU A 150
GLN A  15
 None
 1.17A 6ew0F-3hl1A:
undetectable		 6ew0F-3hl1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		5 / 12 VAL A 183
LEU A  10
ALA A 194
LEU A 150
GLN A  15
 None
 1.18A 6ew0G-3hl1A:
undetectable		 6ew0G-3hl1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		5 / 12 VAL A 183
LEU A  10
LEU A   7
ALA A 194
GLN A  15
 None
 0.86A 6ew0H-3hl1A:
undetectable		 6ew0H-3hl1A:
14.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 3hl1 FERRITIN LIKE
PROTEIN
(Caulobacter
vibrioides) 		5 / 12 VAL A 183
LEU A  10
LEU A   7
ALA A 194
GLN A  15
 None
 0.87A 6ew0I-3hl1A:
undetectable		 6ew0I-3hl1A:
14.19