SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hm0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CPP_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3hm0 PROBABLE
THIOESTERASE
(Bartonella
henselae) 		4 / 7 TYR A  38
THR A  27
LEU A  90
VAL A  22
 None
 1.03A 2cppA-3hm0A:
undetectable		 2cppA-3hm0A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3hm0 PROBABLE
THIOESTERASE
(Bartonella
henselae) 		4 / 8 TYR A  38
THR A  27
LEU A  90
VAL A  22
 None
 1.01A 4l4dA-3hm0A:
undetectable		 4l4dA-3hm0A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3hm0 PROBABLE
THIOESTERASE
(Bartonella
henselae) 		4 / 8 TYR A  38
THR A  27
LEU A  90
VAL A  22
 None
 0.99A 4l4eA-3hm0A:
undetectable		 4l4eA-3hm0A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 3hm0 PROBABLE
THIOESTERASE
(Bartonella
henselae) 		4 / 8 TYR A  38
THR A  27
LEU A  90
VAL A  22
 None
 1.01A 4l4fA-3hm0A:
undetectable		 4l4fA-3hm0A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 3hm0 PROBABLE
THIOESTERASE
(Bartonella
henselae) 		5 / 12 LEU A  60
ASN A  57
PHE A  71
PHE A 104
ILE A  92
 None
 1.33A 6dwnA-3hm0A:
undetectable		 6dwnA-3hm0A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3hm0 PROBABLE
THIOESTERASE
(Bartonella
henselae) 		3 / 3 ALA A 125
PHE A 105
GLN A 100
 None
 0.84A 6eceA-3hm0A:
undetectable		 6eceA-3hm0A:
22.98