SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hm2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE
(Corynebacterium
diphtheriae) 		5 / 12 GLY A  80
GLY A  34
GLY A  32
GLY A  30
ILE A  38
 None
 0.87A 2oxtB-3hm2A:
8.5		 2oxtB-3hm2A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE
(Corynebacterium
diphtheriae) 		3 / 3 ARG A  59
GLU A  53
GLN A  79
 None
 0.96A 2p16A-3hm2A:
undetectable		 2p16A-3hm2A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE
(Corynebacterium
diphtheriae) 		3 / 3 ASP A  28
PHE A  96
LEU A 120
 None
 0.54A 2zi9A-3hm2A:
undetectable		 2zi9A-3hm2A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_2
(ADENOSINE KINASE)		 3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE
(Corynebacterium
diphtheriae) 		4 / 5 LEU A 114
ILE A  29
ALA A 109
PHE A  85
 None
 1.05A 4dc3B-3hm2A:
5.3		 4dc3B-3hm2A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE
(Corynebacterium
diphtheriae) 		5 / 12 GLY A  34
SER A  33
GLU A  53
ILE A  75
ALA A  49
 None
 1.11A 4u8yB-3hm2A:
undetectable		 4u8yB-3hm2A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE
(Corynebacterium
diphtheriae) 		5 / 12 GLY A  34
SER A  33
GLU A  53
ILE A  75
ALA A  49
 None
 1.14A 4u95B-3hm2A:
undetectable		 4u95B-3hm2A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)		 3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE
(Corynebacterium
diphtheriae) 		5 / 9 GLY A  34
SER A  33
GLU A  53
ILE A  75
ALA A  49
 None
 1.27A 5entC-3hm2A:
undetectable		 5entC-3hm2A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EVY_X_SALX502_1
(SALICYLATE
HYDROXYLASE)		 3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE
(Corynebacterium
diphtheriae) 		4 / 5 GLN A 139
MET A 132
LEU A 136
PHE A 140
 None
 1.27A 5evyX-3hm2A:
2.2		 5evyX-3hm2A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE
(Corynebacterium
diphtheriae) 		4 / 7 LEU A 120
ALA A 122
ILE A  36
LEU A  18
 None
 0.92A 5te8C-3hm2A:
undetectable		 5te8C-3hm2A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE
(Corynebacterium
diphtheriae) 		4 / 8 ALA A 122
PHE A 147
SER A 145
THR A 143
 None
 0.93A 5v0vA-3hm2A:
undetectable		 5v0vA-3hm2A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE
(Corynebacterium
diphtheriae) 		5 / 12 GLU A  53
GLY A  80
LEU A  41
GLY A  34
ILE A  62
 None
 1.06A 5vooA-3hm2A:
undetectable		 5vooA-3hm2A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE
(Corynebacterium
diphtheriae) 		5 / 12 GLU A  53
GLY A  80
LEU A  41
GLY A  34
ILE A  62
 None
 1.03A 5vooC-3hm2A:
undetectable		 5vooC-3hm2A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE
(Corynebacterium
diphtheriae) 		5 / 12 GLU A  53
GLY A  80
LEU A  41
GLY A  34
ILE A  62
 None
 1.06A 5vopA-3hm2A:
2.1		 5vopA-3hm2A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_B_9SCB601_1
(SERUM ALBUMIN)		 3hm2 PRECORRIN-6Y
C5,15-METHYLTRANSFER
ASE
(Corynebacterium
diphtheriae) 		4 / 6 ASN A 123
PHE A  96
LEU A 133
SER A 145
 None
 1.36A 6a7pB-3hm2A:
undetectable		 6a7pB-3hm2A:
14.66