SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hmh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3hmh TRANSCRIPTION
INITIATION FACTOR
TFIID 210 KDA
SUBUNIT
(Homo
sapiens) 		4 / 8 TRP A1545
PRO A1546
VAL A1551
ASN A1602
 None
 0.77A 3u5kA-3hmhA:
12.6		 3u5kA-3hmhA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3hmh TRANSCRIPTION
INITIATION FACTOR
TFIID 210 KDA
SUBUNIT
(Homo
sapiens) 		4 / 7 TRP A1545
PRO A1546
VAL A1551
ASN A1602
 None
 0.75A 3u5kB-3hmhA:
12.5		 3u5kB-3hmhA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 3hmh TRANSCRIPTION
INITIATION FACTOR
TFIID 210 KDA
SUBUNIT
(Homo
sapiens) 		4 / 8 TRP A1545
PRO A1546
VAL A1551
ASN A1602
 None
 0.78A 3u5kD-3hmhA:
12.7		 3u5kD-3hmhA:
26.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 3hmh TRANSCRIPTION
INITIATION FACTOR
TFIID 210 KDA
SUBUNIT
(Homo
sapiens) 		5 / 6 PRO A1546
VAL A1551
VAL A1556
TYR A1559
ASN A1602
 None
 0.46A 5pbeA-3hmhA:
13.5		 5pbeA-3hmhA:
39.88