SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hmq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		3 / 3 GLU A  20
ILE A  23
ARG A 186
 None
 0.82A 1cd2A-3hmqA:
1.6		 1cd2A-3hmqA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		5 / 10 LEU A 187
LEU A 195
SER A  60
LEU A  59
LEU A 184
 None
 1.12A 2xn7A-3hmqA:
undetectable
2xn7B-3hmqA:
undetectable		 2xn7A-3hmqA:
21.37
2xn7B-3hmqA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3006_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 6 ASN A 188
ILE A  17
GLU A 239
LYS A  14
 None
 1.39A 3kp6A-3hmqA:
undetectable
3kp6B-3hmqA:
undetectable		 3kp6A-3hmqA:
20.28
3kp6B-3hmqA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		5 / 11 ILE A 111
SER A 148
ILE A 149
VAL A 109
VAL A  81
 None
 1.32A 3rf4B-3hmqA:
undetectable
3rf4C-3hmqA:
undetectable		 3rf4B-3hmqA:
17.34
3rf4C-3hmqA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 7 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.05A 4feuB-3hmqA:
undetectable		 4feuB-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 8 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.03A 4feuD-3hmqA:
undetectable		 4feuD-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 8 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.02A 4feuF-3hmqA:
undetectable		 4feuF-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 7 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.07A 4fevB-3hmqA:
undetectable		 4fevB-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 7 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.07A 4fevD-3hmqA:
undetectable		 4fevD-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 7 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.07A 4fevF-3hmqA:
undetectable		 4fevF-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 7 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.06A 4fewB-3hmqA:
undetectable		 4fewB-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 8 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.09A 4fewD-3hmqA:
undetectable		 4fewD-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 8 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.08A 4fewF-3hmqA:
undetectable		 4fewF-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 7 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.10A 4fexB-3hmqA:
undetectable		 4fexB-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 8 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.09A 4gkhB-3hmqA:
undetectable		 4gkhB-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 8 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.06A 4gkhD-3hmqA:
undetectable		 4gkhD-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 8 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.10A 4gkhF-3hmqA:
undetectable		 4gkhF-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 7 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.09A 4gkhG-3hmqA:
undetectable		 4gkhG-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 6 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.06A 4gkhJ-3hmqA:
undetectable		 4gkhJ-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 8 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.06A 4gkhC-3hmqA:
undetectable
4gkhK-3hmqA:
undetectable		 4gkhC-3hmqA:
25.26
4gkhK-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 8 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.09A 4gkiA-3hmqA:
undetectable		 4gkiA-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 8 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.08A 4gkiC-3hmqA:
undetectable		 4gkiC-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 8 ASP A  52
ASP A 161
ASP A 235
GLU A 165
 SO4  A 276 (-4.9A)
None
None
None
 1.08A 4gkiE-3hmqA:
undetectable
4gkiG-3hmqA:
undetectable		 4gkiE-3hmqA:
25.26
4gkiG-3hmqA:
25.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		5 / 10 ILE A 181
LEU A  59
LEU A 187
PHE A  29
GLU A  22
 None
 1.33A 5tixB-3hmqA:
undetectable		 5tixB-3hmqA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3hmq NH(3)-DEPENDENT
NAD(+) SYNTHETASE
(Salmonella
enterica) 		4 / 6 VAL A  81
ASN A 110
PRO A  84
ILE A 111
 None
SO4  A 282 ( 4.5A)
None
None
 1.23A 6h7uA-3hmqA:
undetectable		 6h7uA-3hmqA:
20.69