SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hmu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 12 LEU A 106
ALA A 333
GLN A 104
HIS A  96
PHE A 119
 None
 1.36A 1brpA-3hmuA:
undetectable		 1brpA-3hmuA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		4 / 8 PHE A 274
GLY A 268
ARG A 269
LEU A 429
 None
 0.73A 1gsfA-3hmuA:
undetectable		 1gsfA-3hmuA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		4 / 8 PHE A 274
GLY A 268
ARG A 269
LEU A 429
 None
 0.73A 1gsfB-3hmuA:
undetectable		 1gsfB-3hmuA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_C_EAAC223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		4 / 8 PHE A 274
GLY A 268
ARG A 269
LEU A 429
 None
 0.73A 1gsfC-3hmuA:
undetectable		 1gsfC-3hmuA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		4 / 8 PHE A 274
GLY A 268
ARG A 269
LEU A 429
 None
 0.73A 1gsfD-3hmuA:
undetectable		 1gsfD-3hmuA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 10 PRO A 229
THR A 270
GLY A 266
CYH A 265
THR A 276
 None
 1.35A 1h4oA-3hmuA:
undetectable
1h4oB-3hmuA:
undetectable		 1h4oA-3hmuA:
15.50
1h4oB-3hmuA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 8 PRO A 229
THR A 270
GLY A 266
CYH A 265
THR A 276
 None
 1.38A 1h4oB-3hmuA:
undetectable		 1h4oB-3hmuA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 9 PRO A 229
THR A 270
GLY A 266
CYH A 265
THR A 276
 None
 1.39A 1h4oC-3hmuA:
undetectable
1h4oD-3hmuA:
undetectable		 1h4oC-3hmuA:
15.50
1h4oD-3hmuA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 9 PRO A 229
THR A 270
GLY A 266
CYH A 265
THR A 276
 None
 1.37A 1h4oD-3hmuA:
undetectable		 1h4oD-3hmuA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 9 PRO A 229
THR A 270
GLY A 266
CYH A 265
THR A 276
 None
 1.37A 1h4oE-3hmuA:
undetectable
1h4oF-3hmuA:
undetectable		 1h4oE-3hmuA:
15.50
1h4oF-3hmuA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 9 PRO A 229
THR A 270
GLY A 266
CYH A 265
THR A 276
 None
 1.37A 1h4oF-3hmuA:
undetectable		 1h4oF-3hmuA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 9 PRO A 229
THR A 270
GLY A 266
CYH A 265
THR A 276
 None
 1.35A 1h4oH-3hmuA:
undetectable		 1h4oH-3hmuA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 9 PRO A 229
THR A 270
GLY A 266
CYH A 265
THR A 276
 None
 1.38A 1hd2A-3hmuA:
undetectable		 1hd2A-3hmuA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 8 PRO A 229
THR A 270
GLY A 266
CYH A 265
THR A 276
 None
 1.34A 1oc3A-3hmuA:
undetectable		 1oc3A-3hmuA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 9 PRO A 229
THR A 270
GLY A 266
CYH A 265
THR A 276
 None
 1.35A 1oc3B-3hmuA:
undetectable		 1oc3B-3hmuA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 GLY A 275
THR A 278
GLU A 262
LEU A 346
GLY A 266
 None
 1.32A 2fn1A-3hmuA:
undetectable		 2fn1A-3hmuA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_A_IPHA2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		4 / 5 HIS A 326
PRO A 327
TYR A 323
TYR A  88
 None
 1.46A 2ombA-3hmuA:
undetectable
2ombB-3hmuA:
undetectable		 2ombA-3hmuA:
15.93
2ombB-3hmuA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 10 PRO A 229
THR A 270
GLY A 266
CYH A 265
THR A 276
 None
 1.39A 2vl2A-3hmuA:
undetectable
2vl2C-3hmuA:
undetectable		 2vl2A-3hmuA:
16.03
2vl2C-3hmuA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XPW_A_OTCA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 12 LEU A 178
HIS A 173
SER A 164
ILE A 226
SER A 151
 None
 1.40A 2xpwA-3hmuA:
undetectable		 2xpwA-3hmuA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		6 / 12 ALA A 126
GLU A 228
ILE A 226
THR A 287
HIS A 184
LEU A 166
 None
 1.39A 3gcsA-3hmuA:
undetectable		 3gcsA-3hmuA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_B_486B1_2
(GLUCOCORTICOID
RECEPTOR)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 12 GLY A 234
GLY A 235
GLN A 231
VAL A 236
ARG A 152
 None
 1.18A 3h52B-3hmuA:
undetectable		 3h52B-3hmuA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 10 ILE A 259
ILE A 149
ASP A 128
SER A 302
HIS A 319
 None
 1.31A 3o1xA-3hmuA:
undetectable		 3o1xA-3hmuA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_A_PFLA319_1
(GLR4197 PROTEIN)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		4 / 7 ILE A 281
LEU A 258
TYR A 243
ILE A 247
 None
 0.98A 3p50A-3hmuA:
undetectable		 3p50A-3hmuA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P50_B_PFLB319_1
(GLR4197 PROTEIN)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		4 / 7 ILE A 281
LEU A 258
TYR A 243
ILE A 247
 None
 0.98A 3p50B-3hmuA:
undetectable		 3p50B-3hmuA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKA_A_SAMA400_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE H)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 12 GLY A 235
GLY A 420
HIS A 418
ARG A 269
SER A 381
 None
 1.38A 3tkaA-3hmuA:
undetectable		 3tkaA-3hmuA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		4 / 6 GLU A 435
ASP A  57
ASN A  66
ARG A 269
 None
 1.21A 4ntxA-3hmuA:
undetectable
4ntxC-3hmuA:
undetectable		 4ntxA-3hmuA:
22.90
4ntxC-3hmuA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_2
(TUBULIN BETA-2B
CHAIN)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 12 LEU A 357
ALA A 380
ILE A 382
ALA A 373
ILE A 425
 None
 0.90A 4o2bD-3hmuA:
undetectable		 4o2bD-3hmuA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.46A 4qvlV-3hmuA:
undetectable
4qvlb-3hmuA:
undetectable		 4qvlV-3hmuA:
19.17
4qvlb-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.46A 4qvlH-3hmuA:
undetectable
4qvlN-3hmuA:
undetectable		 4qvlH-3hmuA:
19.17
4qvlN-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.45A 4qvmV-3hmuA:
undetectable
4qvmb-3hmuA:
undetectable		 4qvmV-3hmuA:
19.17
4qvmb-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.45A 4qvmH-3hmuA:
undetectable
4qvmN-3hmuA:
undetectable		 4qvmH-3hmuA:
19.17
4qvmN-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.45A 4qvpV-3hmuA:
undetectable
4qvpb-3hmuA:
undetectable		 4qvpV-3hmuA:
19.17
4qvpb-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.44A 4qvpH-3hmuA:
undetectable
4qvpN-3hmuA:
undetectable		 4qvpH-3hmuA:
19.17
4qvpN-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.44A 4qvqV-3hmuA:
undetectable
4qvqb-3hmuA:
undetectable		 4qvqV-3hmuA:
19.17
4qvqb-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.44A 4qvqH-3hmuA:
undetectable
4qvqN-3hmuA:
undetectable		 4qvqH-3hmuA:
19.17
4qvqN-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.42A 4qvwV-3hmuA:
undetectable
4qvwb-3hmuA:
undetectable		 4qvwV-3hmuA:
19.17
4qvwb-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.43A 4qvwH-3hmuA:
undetectable
4qvwN-3hmuA:
undetectable		 4qvwH-3hmuA:
19.17
4qvwN-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.43A 4qw0V-3hmuA:
undetectable
4qw0b-3hmuA:
undetectable		 4qw0V-3hmuA:
19.17
4qw0b-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.44A 4qw0H-3hmuA:
undetectable
4qw0N-3hmuA:
undetectable		 4qw0H-3hmuA:
19.17
4qw0N-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.47A 4qw1V-3hmuA:
undetectable
4qw1b-3hmuA:
undetectable		 4qw1V-3hmuA:
19.17
4qw1b-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.46A 4qw1H-3hmuA:
undetectable
4qw1N-3hmuA:
undetectable		 4qw1H-3hmuA:
19.17
4qw1N-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.44A 4qw3V-3hmuA:
undetectable
4qw3b-3hmuA:
undetectable		 4qw3V-3hmuA:
19.17
4qw3b-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.44A 4qw3H-3hmuA:
undetectable
4qw3N-3hmuA:
undetectable		 4qw3H-3hmuA:
19.17
4qw3N-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.46A 4qwuV-3hmuA:
undetectable
4qwub-3hmuA:
undetectable		 4qwuV-3hmuA:
19.17
4qwub-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.46A 4qwuH-3hmuA:
undetectable
4qwuN-3hmuA:
undetectable		 4qwuH-3hmuA:
19.17
4qwuN-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.41A 5cz7H-3hmuA:
undetectable
5cz7N-3hmuA:
undetectable		 5cz7H-3hmuA:
19.17
5cz7N-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.43A 5d0xV-3hmuA:
undetectable
5d0xb-3hmuA:
undetectable		 5d0xV-3hmuA:
19.17
5d0xb-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.45A 5d0xH-3hmuA:
undetectable
5d0xN-3hmuA:
undetectable		 5d0xH-3hmuA:
19.17
5d0xN-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.47A 5l66V-3hmuA:
undetectable
5l66b-3hmuA:
undetectable		 5l66V-3hmuA:
19.17
5l66b-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 11 SER A 324
THR A 287
THR A 129
GLY A 123
ALA A 120
 None
None
None
SO4  A 471 (-3.3A)
None
 1.48A 5l66H-3hmuA:
undetectable
5l66N-3hmuA:
undetectable		 5l66H-3hmuA:
19.17
5l66N-3hmuA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 12 GLY A 377
PRO A 355
ALA A 353
HIS A 348
THR A 270
 None
 1.23A 5x6yA-3hmuA:
undetectable		 5x6yA-3hmuA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		4 / 4 LEU A 447
ASP A 448
GLN A 451
VAL A 238
 None
 1.15A 6bzoF-3hmuA:
undetectable		 6bzoF-3hmuA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 3hmu AMINOTRANSFERASE,
CLASS III
(Ruegeria
pomeroyi) 		5 / 10 GLY A 300
GLY A 301
ILE A 299
ALA A 120
GLY A 325
 None
 1.12A 6e5zA-3hmuA:
undetectable		 6e5zA-3hmuA:
20.90