SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hn6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi)
4 / 8 GLY A 109
SER A 112
ILE A 159
ASP A  72
None
0.84A 1jg4A-3hn6A:
undetectable
1jg4A-3hn6A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi)
3 / 3 ASN A 147
PHE A 134
VAL A 188
None
0.68A 1kijA-3hn6A:
undetectable
1kijA-3hn6A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi)
4 / 8 TYR A   9
ILE A  12
GLY A  47
ILE A 202
None
0.90A 1mrjA-3hn6A:
undetectable
1mrjA-3hn6A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_2
(POL POLYPROTEIN)
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi)
5 / 10 GLY A  38
ILE A 202
GLY A 137
ILE A 144
ALA A 235
None
1.03A 1sh9B-3hn6A:
undetectable
1sh9B-3hn6A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi)
4 / 6 ILE A   4
VAL A 238
ILE A  61
ILE A  97
None
0.85A 1uwhB-3hn6A:
undetectable
1uwhB-3hn6A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi)
4 / 4 ILE A 131
PHE A  69
ILE A  36
THR A 192
None
1.00A 3ia4A-3hn6A:
undetectable
3ia4A-3hn6A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi)
5 / 12 GLY A 139
ILE A 193
GLY A 136
ILE A 202
ILE A 226
None
0.92A 3k4vD-3hn6A:
undetectable
3k4vD-3hn6A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi)
5 / 11 GLY A 139
ILE A 193
GLY A 136
ILE A 202
ILE A 226
None
0.85A 3ndxB-3hn6A:
undetectable
3ndxB-3hn6A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi)
5 / 11 VAL A 199
PHE A  27
GLY A 130
GLY A 129
ILE A 125
None
1.43A 3owxA-3hn6A:
2.3
3owxB-3hn6A:
2.1
3owxA-3hn6A:
21.07
3owxB-3hn6A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi)
4 / 6 ILE A  99
ILE A  24
PHE A  93
LEU A  39
None
0.90A 4m51A-3hn6A:
undetectable
4m51A-3hn6A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi)
5 / 11 GLY A 139
ILE A 193
GLY A 136
ILE A 202
ILE A 226
None
0.93A 4njvC-3hn6A:
undetectable
4njvC-3hn6A:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKB_A_198A1002_2
(ANDROGEN RECEPTOR)
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi)
4 / 6 LEU A 133
MET A  48
MET A 194
VAL A 188
None
1.17A 4okbA-3hn6A:
undetectable
4okbA-3hn6A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_D_P06D801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)
3hn6 GLUCOSAMINE-6-PHOSPH
ATE DEAMINASE

(Borreliella
burgdorferi)
4 / 8 ILE A  46
GLY A  47
PHE A 134
ASN A 204
None
0.72A 5hieD-3hn6A:
undetectable
5hieD-3hn6A:
22.39