SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hn7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HWI_C_115C4_2 (HMG-COA REDUCTASE)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	4 / 8	ASN A 171 LEU A 125 ALA A 122 LEU A 121	None	0.84A	1hwiD-3hn7A: undetectable	1hwiD-3hn7A: 21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1O86_A_LPRA702_2 (ANGIOTENSIN CONVERTING ENZYME)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	4 / 4	SER A 157 VAL A 152 PHE A 175 VAL A 99	None	1.28A	1o86A-3hn7A: undetectable	1o86A-3hn7A: 20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q13_A_TESA501_1 (PROSTAGLANDIN-E2 9-REDUCTASE)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	4 / 6	TYR A 35 HIS A 491 PRO A 432 VAL A 462	None	1.28A	1q13A-3hn7A: undetectable	1q13A-3hn7A: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9Q_A_CHDA459_0 (ESTROGEN-RELATED RECEPTOR GAMMA)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	4 / 6	ASP A 364 LEU A 369 VAL A 370 ILE A 479	None	0.86A	1s9qA-3hn7A: undetectable	1s9qA-3hn7A: 19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VM1_A_TAZA504_1 (BETA-LACTAMASE SHV-1)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	3 / 3	ASP A 183 TYR A 182 GLU A 178	None	0.78A	1vm1A-3hn7A: undetectable	1vm1A-3hn7A: 19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA3_B_STRB2001_1 (MINERALOCORTICOID RECEPTOR)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 12	LEU A 64 ALA A 17 SER A 30 LEU A 6 THR A 89	None	1.36A	1ya3B-3hn7A: undetectable	1ya3B-3hn7A: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FJ1_A_CTCA222_0 (TETRACYCLINE REPRESSOR PROTEIN CLASS D)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 12	SER A 233 HIS A 104 PRO A 198 LEU A 203 ILE A 237	None	1.24A	2fj1A-3hn7A: undetectable	2fj1A-3hn7A: 17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HZQ_A_STRA300_1 (APOLIPOPROTEIN D)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	4 / 7	ALA A 32 TYR A 53 ASN A 33 LEU A 435	None	1.18A	2hzqA-3hn7A: undetectable	2hzqA-3hn7A: 14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_A_SAMA300_1 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	3 / 3	SER A 191 HIS A 377 ASP A 209	None	0.81A	2oxtA-3hn7A: undetectable	2oxtA-3hn7A: 18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OZ7_A_CA4A1_1 (ANDROGEN RECEPTOR)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 12	LEU A 95 GLY A 91 ARG A 404 ALA A 20 LEU A 23	None	1.15A	2oz7A-3hn7A: undetectable	2oz7A-3hn7A: 16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A50_B_VD3B2001_1 (VITAMIN D HYDROXYLASE)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 11	LEU A 349 MET A 120 LEU A 329 ILE A 332 THR A 312	None	1.24A	3a50B-3hn7A: undetectable	3a50B-3hn7A: 22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A50_C_VD3C2001_1 (VITAMIN D HYDROXYLASE)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 11	LEU A 349 MET A 120 LEU A 329 ILE A 332 THR A 312	None	1.27A	3a50C-3hn7A: undetectable	3a50C-3hn7A: 22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CD2_A_MTXA307_1 (DIHYDROFOLATE REDUCTASE)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 12	ILE A 465 LEU A 498 ILE A 479 PHE A 371 ILE A 490	None	1.17A	3cd2A-3hn7A: 3.9	3cd2A-3hn7A: 17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CZH_A_D2VA602_2 (CYTOCHROME P450 2R1)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	3 / 3	LEU A 439 GLU A 402 ILE A 401	None	0.54A	3czhA-3hn7A: undetectable	3czhA-3hn7A: 19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KW4_A_TICA600_1 (CYTOCHROME P450 2B4)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 11	ILE A 466 ILE A 368 ALA A 497 VAL A 370 GLY A 363	None	0.94A	3kw4A-3hn7A: undetectable	3kw4A-3hn7A: 21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WSJ_A_MK1A201_2 (PROTEASE)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	4 / 7	LEU A 125 ALA A 331 VAL A 303 ILE A 124	None	0.68A	3wsjB-3hn7A: undetectable	3wsjB-3hn7A: 12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KTT_C_SAMC404_1 (S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	4 / 8	ALA A 424 ILE A 479 ASP A 477 ILE A 368	None	0.90A	4kttD-3hn7A: undetectable	4kttD-3hn7A: 22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LUH_A_ACTA610_0 (SERUM ALBUMIN)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	3 / 3	VAL A 340 SER A 341 THR A 344	None	0.35A	4luhA-3hn7A: undetectable	4luhA-3hn7A: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PBH_A_BEZA401_0 (TRAP DICARBOXYLATE TRANSPORTER, DCTP SUBUNIT, PUTATIVE)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 12	ILE A 400 TRP A 398 ALA A 473 LEU A 494 LEU A 498	None	1.27A	4pbhA-3hn7A: undetectable	4pbhA-3hn7A: 21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PGF_B_ADNB502_2 (ADENOSYLHOMOCYSTEINA SE)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	4 / 5	THR A 117 THR A 118 HIS A 377 ASN A 205	None	1.31A	4pgfB-3hn7A: 4.8	4pgfB-3hn7A: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q15_A_HFGA803_1 (PROLINE--TRNA LIGASE)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	3 / 3	GLU A 181 THR A 379 HIS A 377	None	0.81A	4q15A-3hn7A: undetectable	4q15A-3hn7A: 21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q15_B_HFGB803_1 (PROLINE--TRNA LIGASE)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	3 / 3	GLU A 181 THR A 379 HIS A 377	None	0.82A	4q15B-3hn7A: undetectable	4q15B-3hn7A: 21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVM_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 9	ALA A 345 THR A 344 ALA A 348 GLY A 339 ALA A 335	None	1.06A	4qvmK-3hn7A: undetectable 4qvmL-3hn7A: undetectable	4qvmK-3hn7A: 17.68 4qvmL-3hn7A: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVN_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 9	ALA A 345 THR A 344 ALA A 348 GLY A 339 ALA A 335	None	1.04A	4qvnK-3hn7A: undetectable 4qvnL-3hn7A: undetectable	4qvnK-3hn7A: 17.33 4qvnL-3hn7A: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVN_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 9	ALA A 345 THR A 344 ALA A 348 GLY A 339 ALA A 335	None	1.04A	4qvnY-3hn7A: undetectable 4qvnZ-3hn7A: undetectable	4qvnY-3hn7A: 17.33 4qvnZ-3hn7A: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVP_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 10	ALA A 345 THR A 344 ALA A 348 GLY A 339 ALA A 335	None	1.05A	4qvpK-3hn7A: undetectable 4qvpL-3hn7A: undetectable	4qvpK-3hn7A: 17.18 4qvpL-3hn7A: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVP_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 10	ALA A 345 THR A 344 ALA A 348 GLY A 339 ALA A 335	None	1.05A	4qvpY-3hn7A: undetectable 4qvpZ-3hn7A: undetectable	4qvpY-3hn7A: 17.18 4qvpZ-3hn7A: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVQ_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 9	ALA A 345 THR A 344 ALA A 348 GLY A 339 ALA A 335	None	1.05A	4qvqK-3hn7A: undetectable 4qvqL-3hn7A: undetectable	4qvqK-3hn7A: 17.56 4qvqL-3hn7A: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVQ_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 9	ALA A 345 THR A 344 ALA A 348 GLY A 339 ALA A 335	None	1.05A	4qvqY-3hn7A: undetectable 4qvqZ-3hn7A: undetectable	4qvqY-3hn7A: 17.56 4qvqZ-3hn7A: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW1_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 11	ALA A 345 THR A 344 ALA A 348 GLY A 339 ALA A 335	None	1.03A	4qw1K-3hn7A: undetectable 4qw1L-3hn7A: undetectable	4qw1K-3hn7A: 17.87 4qw1L-3hn7A: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW1_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 10	ALA A 345 THR A 344 ALA A 348 GLY A 339 ALA A 335	None	1.02A	4qw1Y-3hn7A: undetectable 4qw1Z-3hn7A: undetectable	4qw1Y-3hn7A: 17.87 4qw1Z-3hn7A: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW3_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 10	ALA A 345 THR A 344 ALA A 348 GLY A 339 ALA A 335	None	1.04A	4qw3K-3hn7A: undetectable 4qw3L-3hn7A: undetectable	4qw3K-3hn7A: 17.71 4qw3L-3hn7A: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW3_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 10	ALA A 345 THR A 344 ALA A 348 GLY A 339 ALA A 335	None	1.04A	4qw3Y-3hn7A: undetectable 4qw3Z-3hn7A: undetectable	4qw3Y-3hn7A: 17.71 4qw3Z-3hn7A: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UBE_A_2FAA401_2 (ADENOSINE KINASE)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	4 / 4	ALA A 61 VAL A 65 GLY A 29 THR A 28	None	1.10A	4ubeA-3hn7A: 6.1	4ubeA-3hn7A: 22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YDQ_B_HFGB802_1 (PROLINE--TRNA LIGASE)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	3 / 3	GLU A 181 THR A 379 HIS A 377	None	0.77A	4ydqB-3hn7A: 3.0	4ydqB-3hn7A: 20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D0X_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 9	ALA A 345 THR A 344 ALA A 348 GLY A 339 ALA A 335	None	1.05A	5d0xK-3hn7A: undetectable 5d0xL-3hn7A: undetectable	5d0xK-3hn7A: 17.43 5d0xL-3hn7A: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D0X_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 9	ALA A 345 THR A 344 ALA A 348 GLY A 339 ALA A 335	None	1.05A	5d0xY-3hn7A: undetectable 5d0xZ-3hn7A: undetectable	5d0xY-3hn7A: 17.43 5d0xZ-3hn7A: 16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DXG_B_ESTB601_1 (ESTROGEN RECEPTOR)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	5 / 11	ALA A 291 LEU A 349 GLY A 321 HIS A 323 LEU A 322	None	1.25A	5dxgB-3hn7A: undetectable	5dxgB-3hn7A: 18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGY_A_ERYA403_1 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	4 / 6	TYR A 53 ILE A 34 TYR A 35 TYR A 430	None	1.29A	5igyA-3hn7A: undetectable	5igyA-3hn7A: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NFP_A_8W5A804_2 (GLUCOCORTICOID RECEPTOR)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	4 / 4	LEU A 417 MET A 482 ILE A 453 LEU A 385	None	1.36A	5nfpA-3hn7A: undetectable	5nfpA-3hn7A: 20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HLP_A_GAWA1501_1 (SUBSTANCE-P RECEPTOR,SUBSTANCE-P RECEPTOR)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	4 / 5	ASN A 324 HIS A 376 TYR A 182 MET A 120	None	1.41A	6hlpA-3hn7A: 4.1	6hlpA-3hn7A: 22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HLP_A_GAWA1501_1 (SUBSTANCE-P RECEPTOR,SUBSTANCE-P RECEPTOR)	3hn7	UDP-N-ACETYLMURAMATE -L-ALANINE LIGASE (Psychrobacter arcticus)	4 / 5	ASN A 327 HIS A 376 TYR A 182 MET A 120	None	1.29A	6hlpA-3hn7A: 4.1	6hlpA-3hn7A: 22.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HWI_C_115C4_2","HMG-COA REDUCTASE;HMG-COA REDUCTASE","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",4,"ASN A 171;LEU A 125;ALA A 122;LEU A 121","None","0.84A","1hwiD-3hn7A:undetectable","1hwiD-3hn7A:21.72"],["1O86_A_LPRA702_2","ANGIOTENSIN CONVERTING ENZYME","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",4,"SER A 157;VAL A 152;PHE A 175;VAL A  99","None","1.28A","1o86A-3hn7A:undetectable","1o86A-3hn7A:20.99"],["1Q13_A_TESA501_1","PROSTAGLANDIN-E2 9-REDUCTASE","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",4,"TYR A  35;HIS A 491;PRO A 432;VAL A 462","None","1.28A","1q13A-3hn7A:undetectable","1q13A-3hn7A:21.12"],["1S9Q_A_CHDA459_0","ESTROGEN-RELATED RECEPTOR GAMMA","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",4,"ASP A 364;LEU A 369;VAL A 370;ILE A 479","None","0.86A","1s9qA-3hn7A:undetectable","1s9qA-3hn7A:19.20"],["1VM1_A_TAZA504_1","BETA-LACTAMASE SHV-1","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",3,"ASP A 183;TYR A 182;GLU A 178","None","0.78A","1vm1A-3hn7A:undetectable","1vm1A-3hn7A:19.49"],["1YA3_B_STRB2001_1","MINERALOCORTICOID RECEPTOR","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"LEU A  64;ALA A  17;SER A  30;LEU A   6;THR A  89","None","1.36A","1ya3B-3hn7A:undetectable","1ya3B-3hn7A:20.16"],["2FJ1_A_CTCA222_0","TETRACYCLINE REPRESSOR PROTEIN CLASS D","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"SER A 233;HIS A 104;PRO A 198;LEU A 203;ILE A 237","None","1.24A","2fj1A-3hn7A:undetectable","2fj1A-3hn7A:17.85"],["2HZQ_A_STRA300_1","APOLIPOPROTEIN D","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",4,"ALA A  32;TYR A  53;ASN A  33;LEU A 435","None","1.18A","2hzqA-3hn7A:undetectable","2hzqA-3hn7A:14.51"],["2OXT_A_SAMA300_1","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",3,"SER A 191;HIS A 377;ASP A 209","None","0.81A","2oxtA-3hn7A:undetectable","2oxtA-3hn7A:18.09"],["2OZ7_A_CA4A1_1","ANDROGEN RECEPTOR","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"LEU A  95;GLY A  91;ARG A 404;ALA A  20;LEU A  23","None","1.15A","2oz7A-3hn7A:undetectable","2oz7A-3hn7A:16.21"],["3A50_B_VD3B2001_1","VITAMIN D HYDROXYLASE","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"LEU A 349;MET A 120;LEU A 329;ILE A 332;THR A 312","None","1.24A","3a50B-3hn7A:undetectable","3a50B-3hn7A:22.28"],["3A50_C_VD3C2001_1","VITAMIN D HYDROXYLASE","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"LEU A 349;MET A 120;LEU A 329;ILE A 332;THR A 312","None","1.27A","3a50C-3hn7A:undetectable","3a50C-3hn7A:22.28"],["3CD2_A_MTXA307_1","DIHYDROFOLATE REDUCTASE","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ILE A 465;LEU A 498;ILE A 479;PHE A 371;ILE A 490","None","1.17A","3cd2A-3hn7A:3.9","3cd2A-3hn7A:17.50"],["3CZH_A_D2VA602_2","CYTOCHROME P450 2R1","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",3,"LEU A 439;GLU A 402;ILE A 401","None","0.54A","3czhA-3hn7A:undetectable","3czhA-3hn7A:19.31"],["3KW4_A_TICA600_1","CYTOCHROME P450 2B4","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ILE A 466;ILE A 368;ALA A 497;VAL A 370;GLY A 363","None","0.94A","3kw4A-3hn7A:undetectable","3kw4A-3hn7A:21.83"],["3WSJ_A_MK1A201_2","PROTEASE;PROTEASE","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",4,"LEU A 125;ALA A 331;VAL A 303;ILE A 124","None","0.68A","3wsjB-3hn7A:undetectable","3wsjB-3hn7A:12.06"],["4KTT_C_SAMC404_1","S-ADENOSYLMETHIONINE SYNTHASE ISOFORM TYPE-2","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",4,"ALA A 424;ILE A 479;ASP A 477;ILE A 368","None","0.90A","4kttD-3hn7A:undetectable","4kttD-3hn7A:22.27"],["4LUH_A_ACTA610_0","SERUM ALBUMIN","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",3,"VAL A 340;SER A 341;THR A 344","None","0.35A","4luhA-3hn7A:undetectable","4luhA-3hn7A:21.43"],["4PBH_A_BEZA401_0","TRAP DICARBOXYLATE TRANSPORTER, DCTP SUBUNIT, PUTATIVE","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ILE A 400;TRP A 398;ALA A 473;LEU A 494;LEU A 498","None","1.27A","4pbhA-3hn7A:undetectable","4pbhA-3hn7A:21.42"],["4PGF_B_ADNB502_2","ADENOSYLHOMOCYSTEINASE","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",4,"THR A 117;THR A 118;HIS A 377;ASN A 205","None","1.31A","4pgfB-3hn7A:4.8","4pgfB-3hn7A:22.45"],["4Q15_A_HFGA803_1","PROLINE--TRNA LIGASE","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",3,"GLU A 181;THR A 379;HIS A 377","None","0.81A","4q15A-3hn7A:undetectable","4q15A-3hn7A:21.27"],["4Q15_B_HFGB803_1","PROLINE--TRNA LIGASE","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",3,"GLU A 181;THR A 379;HIS A 377","None","0.82A","4q15B-3hn7A:undetectable","4q15B-3hn7A:21.27"],["4QVM_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ALA A 345;THR A 344;ALA A 348;GLY A 339;ALA A 335","None","1.06A","4qvmK-3hn7A:undetectable;4qvmL-3hn7A:undetectable","4qvmK-3hn7A:17.68;4qvmL-3hn7A:16.96"],["4QVN_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ALA A 345;THR A 344;ALA A 348;GLY A 339;ALA A 335","None","1.04A","4qvnK-3hn7A:undetectable;4qvnL-3hn7A:undetectable","4qvnK-3hn7A:17.33;4qvnL-3hn7A:16.96"],["4QVN_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ALA A 345;THR A 344;ALA A 348;GLY A 339;ALA A 335","None","1.04A","4qvnY-3hn7A:undetectable;4qvnZ-3hn7A:undetectable","4qvnY-3hn7A:17.33;4qvnZ-3hn7A:16.96"],["4QVP_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ALA A 345;THR A 344;ALA A 348;GLY A 339;ALA A 335","None","1.05A","4qvpK-3hn7A:undetectable;4qvpL-3hn7A:undetectable","4qvpK-3hn7A:17.18;4qvpL-3hn7A:16.96"],["4QVP_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ALA A 345;THR A 344;ALA A 348;GLY A 339;ALA A 335","None","1.05A","4qvpY-3hn7A:undetectable;4qvpZ-3hn7A:undetectable","4qvpY-3hn7A:17.18;4qvpZ-3hn7A:16.96"],["4QVQ_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ALA A 345;THR A 344;ALA A 348;GLY A 339;ALA A 335","None","1.05A","4qvqK-3hn7A:undetectable;4qvqL-3hn7A:undetectable","4qvqK-3hn7A:17.56;4qvqL-3hn7A:16.96"],["4QVQ_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ALA A 345;THR A 344;ALA A 348;GLY A 339;ALA A 335","None","1.05A","4qvqY-3hn7A:undetectable;4qvqZ-3hn7A:undetectable","4qvqY-3hn7A:17.56;4qvqZ-3hn7A:16.96"],["4QW1_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ALA A 345;THR A 344;ALA A 348;GLY A 339;ALA A 335","None","1.03A","4qw1K-3hn7A:undetectable;4qw1L-3hn7A:undetectable","4qw1K-3hn7A:17.87;4qw1L-3hn7A:16.96"],["4QW1_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ALA A 345;THR A 344;ALA A 348;GLY A 339;ALA A 335","None","1.02A","4qw1Y-3hn7A:undetectable;4qw1Z-3hn7A:undetectable","4qw1Y-3hn7A:17.87;4qw1Z-3hn7A:16.96"],["4QW3_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ALA A 345;THR A 344;ALA A 348;GLY A 339;ALA A 335","None","1.04A","4qw3K-3hn7A:undetectable;4qw3L-3hn7A:undetectable","4qw3K-3hn7A:17.71;4qw3L-3hn7A:16.96"],["4QW3_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ALA A 345;THR A 344;ALA A 348;GLY A 339;ALA A 335","None","1.04A","4qw3Y-3hn7A:undetectable;4qw3Z-3hn7A:undetectable","4qw3Y-3hn7A:17.71;4qw3Z-3hn7A:16.96"],["4UBE_A_2FAA401_2","ADENOSINE KINASE","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",4,"ALA A  61;VAL A  65;GLY A  29;THR A  28","None","1.10A","4ubeA-3hn7A:6.1","4ubeA-3hn7A:22.14"],["4YDQ_B_HFGB802_1","PROLINE--TRNA LIGASE","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",3,"GLU A 181;THR A 379;HIS A 377","None","0.77A","4ydqB-3hn7A:3.0","4ydqB-3hn7A:20.71"],["5D0X_K_BO2K301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ALA A 345;THR A 344;ALA A 348;GLY A 339;ALA A 335","None","1.05A","5d0xK-3hn7A:undetectable;5d0xL-3hn7A:undetectable","5d0xK-3hn7A:17.43;5d0xL-3hn7A:16.96"],["5D0X_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ALA A 345;THR A 344;ALA A 348;GLY A 339;ALA A 335","None","1.05A","5d0xY-3hn7A:undetectable;5d0xZ-3hn7A:undetectable","5d0xY-3hn7A:17.43;5d0xZ-3hn7A:16.96"],["5DXG_B_ESTB601_1","ESTROGEN RECEPTOR","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",5,"ALA A 291;LEU A 349;GLY A 321;HIS A 323;LEU A 322","None","1.25A","5dxgB-3hn7A:undetectable","5dxgB-3hn7A:18.25"],["5IGY_A_ERYA403_1","MACROLIDE 2'-PHOSPHOTRANSFERASE II","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",4,"TYR A  53;ILE A  34;TYR A  35;TYR A 430","None","1.29A","5igyA-3hn7A:undetectable","5igyA-3hn7A:20.83"],["5NFP_A_8W5A804_2","GLUCOCORTICOID RECEPTOR","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",4,"LEU A 417;MET A 482;ILE A 453;LEU A 385","None","1.36A","5nfpA-3hn7A:undetectable","5nfpA-3hn7A:20.65"],["6HLP_A_GAWA1501_1","SUBSTANCE-P RECEPTOR,SUBSTANCE-P RECEPTOR","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",4,"ASN A 324;HIS A 376;TYR A 182;MET A 120","None","1.41A","6hlpA-3hn7A:4.1","6hlpA-3hn7A:22.52"],["6HLP_A_GAWA1501_1","SUBSTANCE-P RECEPTOR,SUBSTANCE-P RECEPTOR","3hn7","UDP-N-ACETYLMURAMATE-L-ALANINE LIGASE","Psychrobacter arcticus",4,"ASN A 327;HIS A 376;TYR A 182;MET A 120","None","1.29A","6hlpA-3hn7A:4.1","6hlpA-3hn7A:22.52"]]