SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hnp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 6 LEU A 298
ASP A 300
GLU A 271
ARG A  25
 None
 1.06A 1mt1A-3hnpA:
undetectable
1mt1F-3hnpA:
undetectable		 1mt1A-3hnpA:
10.29
1mt1F-3hnpA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_B_AG2B7001_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 6 GLU A 271
ARG A  25
LEU A 298
ASP A 300
 None
 0.95A 1mt1B-3hnpA:
undetectable
1mt1C-3hnpA:
undetectable		 1mt1B-3hnpA:
16.23
1mt1C-3hnpA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KIV_A_ACAA100_1
(APOLIPOPROTEIN)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 7 ARG A 182
ASP A 128
ASP A 252
PHE A 237
 None
 1.45A 3kivA-3hnpA:
undetectable		 3kivA-3hnpA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		5 / 12 GLU A 324
ILE A 184
ALA A 325
THR A 327
ILE A 331
 None
 1.14A 3ndiA-3hnpA:
3.4		 3ndiA-3hnpA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 5 GLY A 129
ASP A 252
GLN A 123
MET A 120
 None
 1.03A 3qx3A-3hnpA:
undetectable		 3qx3A-3hnpA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 5 GLY A 129
ASP A 252
GLN A 123
MET A 120
 None
 1.04A 3qx3B-3hnpA:
undetectable		 3qx3B-3hnpA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 7 PHE A 210
ASP A 207
PHE A 172
GLY A 176
 None
 1.15A 3vnsA-3hnpA:
3.8		 3vnsA-3hnpA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		3 / 3 TYR A 155
HIS A 228
ARG A 157
 None
 0.88A 4e7bC-3hnpA:
3.1		 4e7bC-3hnpA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2F_A_ADNA601_1
(5'-NUCLEOTIDASE)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		5 / 9 GLY A 299
GLY A 270
PHE A 269
GLY A 129
ASP A 252
 None
 1.47A 4h2fA-3hnpA:
undetectable		 4h2fA-3hnpA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4H2G_A_ADNA603_1
(5'-NUCLEOTIDASE)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		5 / 9 GLY A 299
GLY A 270
PHE A 269
GLY A 129
ASP A 252
 None
 1.40A 4h2gA-3hnpA:
undetectable		 4h2gA-3hnpA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		6 / 12 LEU A 332
ASP A 181
ILE A 177
GLY A 176
VAL A 212
LEU A 214
 None
 1.49A 4y8wA-3hnpA:
undetectable		 4y8wA-3hnpA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		6 / 12 LEU A 332
ASP A 181
ILE A 177
GLY A 176
VAL A 212
LEU A 214
 None
 1.48A 4y8wB-3hnpA:
undetectable		 4y8wB-3hnpA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 6 TYR A 155
GLY A 170
SER A 174
LEU A 175
 None
 0.87A 5bphA-3hnpA:
undetectable		 5bphA-3hnpA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_B_ACTB404_0
(D-ALANINE--D-ALANINE
LIGASE)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 7 TYR A 155
GLY A 170
SER A 174
LEU A 175
 None
 0.84A 5bphB-3hnpA:
6.3		 5bphB-3hnpA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 4 TYR A 155
GLY A 170
SER A 174
LEU A 175
 None
 0.89A 5bphC-3hnpA:
6.1		 5bphC-3hnpA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 6 TYR A 155
GLY A 170
SER A 174
LEU A 175
 None
 0.83A 5bphD-3hnpA:
6.0		 5bphD-3hnpA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 7 ILE A  86
VAL A  30
ILE A  66
PHE A   7
 None
 0.75A 5hieC-3hnpA:
undetectable		 5hieC-3hnpA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 6 TYR A 305
HIS A  18
ILE A  33
TYR A  46
 None
 1.13A 5ih0A-3hnpA:
undetectable		 5ih0A-3hnpA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 8 ARG A 303
GLY A 129
LEU A 132
THR A 296
 None
 0.82A 5sxqA-3hnpA:
undetectable		 5sxqA-3hnpA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 8 ARG A 303
GLY A 129
LEU A 132
THR A 296
 None
 0.75A 5sxtA-3hnpA:
undetectable		 5sxtA-3hnpA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 8 ARG A 303
GLY A 129
LEU A 132
THR A 296
 None
 0.78A 5sxtB-3hnpA:
undetectable		 5sxtB-3hnpA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 3hnp OXIDOREDUCTASE
(Bacillus
cereus) 		4 / 8 ARG A 303
GLY A 129
LEU A 132
THR A 296
 None
 0.78A 5syjB-3hnpA:
undetectable		 5syjB-3hnpA:
18.66