SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hnq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TDN_A_LEUA487_0 (L-AMINO ACID OXIDASE)	3hnq	VIRULENCE PROTEIN STM3117 (Salmonella enterica)	4 / 7	ASN A 67 HIS A 69 PHE A 75 ILE A 34	None	1.16A	1tdnA-3hnqA: undetectable	1tdnA-3hnqA: 13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3O94_B_NCAB192_0 (NICOTINAMIDASE)	3hnq	VIRULENCE PROTEIN STM3117 (Salmonella enterica)	5 / 11	LEU A 45 ASP A 132 PHE A 91 LEU A 59 ILE A 66	None	1.26A	3o94B-3hnqA: undetectable	3o94B-3hnqA: 24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AFG_B_QMRB1214_1 (CAPITELLA TELETA ACHBP)	3hnq	VIRULENCE PROTEIN STM3117 (Salmonella enterica)	5 / 9	ILE A 109 ILE A 140 PHE A 61 VAL A 44 TYR A 41	None	1.50A	4afgA-3hnqA: undetectable 4afgE-3hnqA: undetectable	4afgA-3hnqA: 19.75 4afgE-3hnqA: 19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RMJ_A_NCAA402_0 (NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2)	3hnq	VIRULENCE PROTEIN STM3117 (Salmonella enterica)	4 / 7	PHE A 61 LEU A 27 ILE A 24 ASP A 25	None	0.79A	4rmjA-3hnqA: undetectable	4rmjA-3hnqA: 19.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TDN_A_LEUA487_0","L-AMINO ACID OXIDASE","3hnq","VIRULENCE PROTEIN STM3117","Salmonella enterica",4,"ASN A  67;HIS A  69;PHE A  75;ILE A  34","None","1.16A","1tdnA-3hnqA:undetectable","1tdnA-3hnqA:13.17"],["3O94_B_NCAB192_0","NICOTINAMIDASE","3hnq","VIRULENCE PROTEIN STM3117","Salmonella enterica",5,"LEU A  45;ASP A 132;PHE A  91;LEU A  59;ILE A  66","None","1.26A","3o94B-3hnqA:undetectable","3o94B-3hnqA:24.06"],["4AFG_B_QMRB1214_1","CAPITELLA TELETA ACHBP;CAPITELLA TELETA ACHBP;CAPITELLA TELETA ACHBP","3hnq","VIRULENCE PROTEIN STM3117","Salmonella enterica",5,"ILE A 109;ILE A 140;PHE A  61;VAL A  44;TYR A  41","None","1.50A","4afgA-3hnqA:undetectable;4afgE-3hnqA:undetectable","4afgA-3hnqA:19.75;4afgE-3hnqA:19.75"],["4RMJ_A_NCAA402_0","NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2","3hnq","VIRULENCE PROTEIN STM3117","Salmonella enterica",4,"PHE A  61;LEU A  27;ILE A  24;ASP A  25","None","0.79A","4rmjA-3hnqA:undetectable","4rmjA-3hnqA:19.21"]]