SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hns'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3hns CS-35 FAB HEAVY
CHAIN
(Mus
musculus) 		4 / 5 VAL H 171
SER H 181
VAL H 174
SER H 183
 None
 1.08A 2j9cA-3hnsH:
undetectable
2j9cB-3hnsH:
undetectable
2j9cC-3hnsH:
undetectable		 2j9cA-3hnsH:
18.06
2j9cB-3hnsH:
18.06
2j9cC-3hnsH:
18.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 3hns CS-35 FAB HEAVY
CHAIN
(Mus
musculus) 		4 / 5 VAL H   2
TYR H  27
ARG H  98
TYR H 107
 None
 0.15A 4m7kH-3hnsH:
28.1		 4m7kH-3hnsH:
64.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 3hns CS-35 FAB HEAVY
CHAIN
(Mus
musculus) 		4 / 5 SER H 117
ALA H 119
PHE H 151
LEU H 175
 None
 0.32A 5mthA-3hnsH:
29.4		 5mthA-3hnsH:
67.42