SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hp4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 3hp4 GDSL-ESTERASE
(Pseudoalteromona
s
sp.
643A) 		5 / 11 GLN A 167
LEU A  12
ALA A 166
MET A 155
ASP A 147
 None
MIR  A  11 ( 4.2A)
None
None
None
 1.28A 2c12F-3hp4A:
undetectable		 2c12F-3hp4A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 3hp4 GDSL-ESTERASE
(Pseudoalteromona
s
sp.
643A) 		5 / 12 LEU A  92
LEU A  95
VAL A  96
SER A  99
LEU A 140
 None
 1.09A 3m7rA-3hp4A:
undetectable		 3m7rA-3hp4A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3hp4 GDSL-ESTERASE
(Pseudoalteromona
s
sp.
643A) 		5 / 11 GLN A 100
ALA A 101
THR A 136
ILE A 132
ASP A 135
 None
 1.17A 4uuuA-3hp4A:
undetectable
4uuuB-3hp4A:
undetectable		 4uuuA-3hp4A:
20.53
4uuuB-3hp4A:
20.53