SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hp7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		4 / 6 LEU A 148
ILE A  87
ASP A 143
PRO A 141
 None
 1.12A 1ditH-3hp7A:
undetectable
1ditP-3hp7A:
undetectable		 1ditH-3hp7A:
18.24
1ditP-3hp7A:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_A_CAMA502_0
(CYTOCHROME P450-CAM)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		4 / 6 PHE A  77
LEU A 181
VAL A 261
ASP A 227
 None
 1.17A 1dz4A-3hp7A:
undetectable		 1dz4A-3hp7A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		4 / 6 PHE A  77
LEU A 181
VAL A 261
ASP A 227
 None
 1.16A 1dz4B-3hp7A:
undetectable		 1dz4B-3hp7A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		4 / 5 PHE A  77
LEU A 181
VAL A 261
ASP A 227
 None
 1.15A 1dz6A-3hp7A:
undetectable		 1dz6A-3hp7A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		4 / 8 ASP A 174
GLY A 176
SER A 222
ASP A 248
 None
 0.76A 1m4iA-3hp7A:
undetectable		 1m4iA-3hp7A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 ILE A  87
ILE A  89
ILE A 164
PHE A 136
LEU A 165
 None
 1.00A 1qhsA-3hp7A:
undetectable		 1qhsA-3hp7A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0F_A_STRA1499_1
(CYTOCHROME P450 3A4)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		4 / 4 PHE A 151
ASP A  88
PHE A  96
VAL A 179
 None
 1.33A 1w0fA-3hp7A:
undetectable		 1w0fA-3hp7A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_1
(ADENOSYLHOMOCYSTEINA
SE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 LEU A 122
THR A  93
GLU A  52
LEU A  70
GLY A  66
 None
 1.04A 1xwfA-3hp7A:
3.5		 1xwfA-3hp7A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_1
(ADENOSYLHOMOCYSTEINA
SE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 LEU A 122
THR A  93
GLU A  52
LEU A  70
GLY A  66
 None
 1.04A 1xwfB-3hp7A:
5.1		 1xwfB-3hp7A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_1
(ADENOSYLHOMOCYSTEINA
SE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 LEU A 122
THR A  93
GLU A  52
LEU A  70
GLY A  66
 None
 1.04A 1xwfC-3hp7A:
6.2		 1xwfC-3hp7A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_1
(ADENOSYLHOMOCYSTEINA
SE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 LEU A 122
THR A  93
GLU A  52
LEU A  70
GLY A  66
 None
 1.03A 1xwfD-3hp7A:
5.1		 1xwfD-3hp7A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 PHE A 136
LEU A 168
VAL A 179
HIS A 243
LEU A  79
 None
 1.40A 2hc4A-3hp7A:
undetectable		 2hc4A-3hp7A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 GLY A  66
GLY A  90
GLY A  95
ASP A 155
VAL A 156
 None
EOH  A 301 ( 3.7A)
None
None
None
 0.74A 2oxtA-3hp7A:
14.6		 2oxtA-3hp7A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		6 / 12 GLY A  66
ASP A  88
GLY A  90
GLY A  95
ASP A 155
VAL A 156
 None
None
EOH  A 301 ( 3.7A)
None
None
None
 0.73A 2oxtD-3hp7A:
13.3		 2oxtD-3hp7A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		4 / 6 PHE A  77
LEU A 181
VAL A 261
ASP A 227
 None
 1.19A 2zawA-3hp7A:
undetectable		 2zawA-3hp7A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 8 VAL A 128
GLY A  94
THR A  97
GLY A  90
ALA A  91
 None
None
None
EOH  A 301 ( 3.7A)
None
 1.38A 3aruA-3hp7A:
undetectable		 3aruA-3hp7A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 GLY A  66
GLY A  90
GLY A  95
ASN A 135
ASP A 155
 None
EOH  A 301 ( 3.7A)
None
None
None
 0.44A 3eluA-3hp7A:
14.2		 3eluA-3hp7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 GLY A  66
GLY A  90
GLY A  95
ASN A 135
ASP A 155
 None
EOH  A 301 ( 3.7A)
None
None
None
 0.49A 3elwA-3hp7A:
12.7		 3elwA-3hp7A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 GLY A  66
GLY A  90
GLY A  95
ASN A 135
ASP A 155
 None
EOH  A 301 ( 3.7A)
None
None
None
 0.44A 3embA-3hp7A:
14.4		 3embA-3hp7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		6 / 12 SER A  64
GLY A  90
GLY A  94
GLY A  95
ASP A 112
ASP A 155
 None
EOH  A 301 ( 3.7A)
None
None
EOH  A 301 (-4.0A)
None
 0.57A 4b17A-3hp7A:
16.9		 4b17A-3hp7A:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 SER A  64
GLY A  66
GLY A  90
GLY A  95
ASP A 155
 None
None
EOH  A 301 ( 3.7A)
None
None
 0.76A 4ctkC-3hp7A:
13.8		 4ctkC-3hp7A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		4 / 6 PHE A  77
LEU A 181
VAL A 261
ASP A 227
 None
 1.12A 4g3rA-3hp7A:
undetectable		 4g3rA-3hp7A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G3R_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		4 / 6 PHE A  77
LEU A 181
VAL A 261
ASP A 227
 None
 1.12A 4g3rB-3hp7A:
undetectable		 4g3rB-3hp7A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KKY_X_CAMX503_0
(CAMPHOR
5-MONOOXYGENASE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		4 / 6 PHE A  77
LEU A 181
VAL A 261
ASP A 227
 None
 1.17A 4kkyX-3hp7A:
undetectable		 4kkyX-3hp7A:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		4 / 6 PHE A  77
LEU A 181
VAL A 261
ASP A 227
 None
 1.11A 4l4cA-3hp7A:
undetectable		 4l4cA-3hp7A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_1
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 ASP A 112
SER A  64
GLY A  90
ASP A 155
LYS A  69
 EOH  A 301 (-4.0A)
None
EOH  A 301 ( 3.7A)
None
None
 1.11A 4pevB-3hp7A:
undetectable		 4pevB-3hp7A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_F_PARF500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 11 SER A  92
SER A 153
GLU A  71
GLU A  58
GLY A  66
 None
 1.44A 4qb9F-3hp7A:
undetectable		 4qb9F-3hp7A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		4 / 4 PHE A  96
ASP A  88
GLY A  67
SER A 153
 None
 1.46A 4xp9C-3hp7A:
undetectable		 4xp9C-3hp7A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 SER A  64
GLY A  66
GLY A  90
GLY A  95
ASP A 155
 None
None
EOH  A 301 ( 3.7A)
None
None
 0.73A 5ec8A-3hp7A:
13.9		 5ec8A-3hp7A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 SER A  64
GLY A  66
GLY A  90
GLY A  95
ASP A 155
 None
None
EOH  A 301 ( 3.7A)
None
None
 0.74A 5ekxA-3hp7A:
14.0		 5ekxA-3hp7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O45_B_CCSB13_0
(PHE-MEA-9KK-SAR-ASP-
VAL-MEA-TYR-SAR-TRP-
TYR-LEU-CCS-GLY-NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 9 GLU A 239
ASN A 237
VAL A 199
PHE A 186
LEU A 181
 None
 1.47A 5o45A-3hp7A:
0.0
5o45B-3hp7A:
undetectable		 5o45A-3hp7A:
17.79
5o45B-3hp7A:
9.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_1
(RIBOFLAVIN LYASE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 PHE A 151
GLY A 104
ALA A 105
VAL A  99
THR A  86
 None
 0.93A 5w4zA-3hp7A:
undetectable		 5w4zA-3hp7A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_1
(RIBOFLAVIN LYASE)		 3hp7 HEMOLYSIN, PUTATIVE
(Streptococcus
thermophilus) 		5 / 12 PHE A 151
GLY A 104
ALA A 105
VAL A  99
THR A  86
 None
 0.95A 5w4zB-3hp7A:
undetectable		 5w4zB-3hp7A:
14.89