SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hpa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
6 / 12 HIS A  93
HIS A  95
HIS A 259
GLU A 262
HIS A 296
ASP A 347
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
None
ZN  A 480 ( 4.8A)
ZN  A 480 (-3.2A)
1.00A 1a4lA-3hpaA:
22.9
1a4lA-3hpaA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 HIS A  93
MET A 184
HIS A 259
GLU A 262
HIS A 296
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.5A)
None
ZN  A 480 ( 4.8A)
1.06A 1a4lA-3hpaA:
22.9
1a4lA-3hpaA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 HIS A  95
HIS A 259
GLU A 262
HIS A 296
ASP A 347
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
None
ZN  A 480 ( 4.8A)
ZN  A 480 (-3.2A)
0.99A 1a4lB-3hpaA:
22.9
1a4lB-3hpaA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 HIS A  95
LEU A 116
HIS A 259
GLU A 262
HIS A 296
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.5A)
None
ZN  A 480 ( 4.8A)
1.08A 1a4lB-3hpaA:
22.9
1a4lB-3hpaA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
6 / 12 HIS A  93
HIS A  95
HIS A 259
GLU A 262
HIS A 296
ASP A 347
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
None
ZN  A 480 ( 4.8A)
ZN  A 480 (-3.2A)
0.92A 1a4lC-3hpaA:
22.7
1a4lC-3hpaA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 8 HIS A 259
HIS A  93
HIS A 296
HIS A  95
ZN  A 480 (-3.5A)
ZN  A 480 (-3.3A)
ZN  A 480 ( 4.8A)
ZN  A 480 (-3.3A)
1.01A 1bzmA-3hpaA:
undetectable
1bzmA-3hpaA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.19A 1c9sA-3hpaA:
undetectable
1c9sK-3hpaA:
undetectable
1c9sA-3hpaA:
10.65
1c9sK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.18A 1c9sA-3hpaA:
undetectable
1c9sB-3hpaA:
undetectable
1c9sA-3hpaA:
10.65
1c9sB-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 1c9sB-3hpaA:
undetectable
1c9sC-3hpaA:
undetectable
1c9sB-3hpaA:
10.65
1c9sC-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 1c9sC-3hpaA:
undetectable
1c9sD-3hpaA:
undetectable
1c9sC-3hpaA:
10.65
1c9sD-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 1c9sD-3hpaA:
undetectable
1c9sE-3hpaA:
undetectable
1c9sD-3hpaA:
10.65
1c9sE-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 1c9sE-3hpaA:
undetectable
1c9sF-3hpaA:
undetectable
1c9sE-3hpaA:
10.65
1c9sF-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.22A 1c9sF-3hpaA:
undetectable
1c9sG-3hpaA:
undetectable
1c9sF-3hpaA:
10.65
1c9sG-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 1c9sG-3hpaA:
undetectable
1c9sH-3hpaA:
undetectable
1c9sG-3hpaA:
10.65
1c9sH-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 1c9sH-3hpaA:
undetectable
1c9sI-3hpaA:
undetectable
1c9sH-3hpaA:
10.65
1c9sI-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 1c9sJ-3hpaA:
undetectable
1c9sK-3hpaA:
undetectable
1c9sJ-3hpaA:
10.65
1c9sK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.19A 1c9sL-3hpaA:
undetectable
1c9sM-3hpaA:
undetectable
1c9sL-3hpaA:
10.65
1c9sM-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.21A 1c9sM-3hpaA:
undetectable
1c9sN-3hpaA:
undetectable
1c9sM-3hpaA:
10.65
1c9sN-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.21A 1c9sO-3hpaA:
undetectable
1c9sP-3hpaA:
undetectable
1c9sO-3hpaA:
10.65
1c9sP-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 1c9sQ-3hpaA:
undetectable
1c9sR-3hpaA:
undetectable
1c9sQ-3hpaA:
10.65
1c9sR-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 1c9sS-3hpaA:
undetectable
1c9sT-3hpaA:
undetectable
1c9sS-3hpaA:
10.65
1c9sT-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 8 ASP A 347
HIS A  93
HIS A 259
HIS A 296
ZN  A 480 (-3.2A)
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
ZN  A 480 ( 4.8A)
0.97A 1ei6D-3hpaA:
undetectable
1ei6D-3hpaA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.18A 1gtfA-3hpaA:
undetectable
1gtfK-3hpaA:
undetectable
1gtfA-3hpaA:
10.65
1gtfK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 1gtfA-3hpaA:
undetectable
1gtfB-3hpaA:
undetectable
1gtfA-3hpaA:
10.65
1gtfB-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 1gtfC-3hpaA:
undetectable
1gtfD-3hpaA:
undetectable
1gtfC-3hpaA:
10.65
1gtfD-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 1gtfD-3hpaA:
undetectable
1gtfE-3hpaA:
undetectable
1gtfD-3hpaA:
10.65
1gtfE-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 1gtfE-3hpaA:
undetectable
1gtfF-3hpaA:
undetectable
1gtfE-3hpaA:
10.65
1gtfF-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 1gtfF-3hpaA:
undetectable
1gtfG-3hpaA:
undetectable
1gtfF-3hpaA:
10.65
1gtfG-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 1gtfG-3hpaA:
undetectable
1gtfH-3hpaA:
undetectable
1gtfG-3hpaA:
10.65
1gtfH-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 1gtfH-3hpaA:
undetectable
1gtfI-3hpaA:
undetectable
1gtfH-3hpaA:
10.65
1gtfI-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 1gtfI-3hpaA:
undetectable
1gtfJ-3hpaA:
undetectable
1gtfI-3hpaA:
10.65
1gtfJ-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.21A 1gtfO-3hpaA:
undetectable
1gtfP-3hpaA:
undetectable
1gtfO-3hpaA:
10.65
1gtfP-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 1gtfR-3hpaA:
undetectable
1gtfS-3hpaA:
undetectable
1gtfR-3hpaA:
10.65
1gtfS-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 1gtfT-3hpaA:
undetectable
1gtfU-3hpaA:
undetectable
1gtfT-3hpaA:
10.65
1gtfU-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3hpa AMIDOHYDROLASE
(unidentified)
5 / 11 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.21A 1gtfU-3hpaA:
undetectable
1gtfV-3hpaA:
undetectable
1gtfU-3hpaA:
10.65
1gtfV-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 1gtfL-3hpaA:
undetectable
1gtfV-3hpaA:
undetectable
1gtfL-3hpaA:
10.65
1gtfV-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.18A 1gtnG-3hpaA:
undetectable
1gtnH-3hpaA:
undetectable
1gtnG-3hpaA:
10.65
1gtnH-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.17A 1gtnH-3hpaA:
undetectable
1gtnI-3hpaA:
undetectable
1gtnH-3hpaA:
10.65
1gtnI-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 1gtnL-3hpaA:
undetectable
1gtnM-3hpaA:
undetectable
1gtnL-3hpaA:
10.65
1gtnM-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.19A 1gtnN-3hpaA:
undetectable
1gtnO-3hpaA:
undetectable
1gtnN-3hpaA:
10.65
1gtnO-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 8 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 1gtnP-3hpaA:
undetectable
1gtnQ-3hpaA:
undetectable
1gtnP-3hpaA:
10.65
1gtnQ-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.19A 1gtnR-3hpaA:
undetectable
1gtnS-3hpaA:
undetectable
1gtnR-3hpaA:
10.65
1gtnS-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 1gtnS-3hpaA:
undetectable
1gtnT-3hpaA:
undetectable
1gtnS-3hpaA:
10.65
1gtnT-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRL_B_DOLB301_1
(STREPTOGRAMIN A
ACETYLTRANSFERASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 TYR A  97
ILE A 131
LEU A 163
VAL A 346
ASP A 347
None
None
None
None
ZN  A 480 (-3.2A)
1.49A 1mrlB-3hpaA:
undetectable
1mrlC-3hpaA:
undetectable
1mrlB-3hpaA:
18.12
1mrlC-3hpaA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 11 LEU A  89
GLY A  88
LEU A 402
LEU A 431
LEU A 383
None
1.32A 1mx1B-3hpaA:
undetectable
1mx1B-3hpaA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 5 HIS A  94
HIS A 296
HIS A  93
HIS A 259
None
ZN  A 480 ( 4.8A)
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
1.12A 1os2A-3hpaA:
undetectable
1os2A-3hpaA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 5 HIS A 294
HIS A  93
HIS A 259
HIS A 153
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
None
1.12A 1os2A-3hpaA:
undetectable
1os2A-3hpaA:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLN A  98
HIS A  95
HIS A  93
HIS A 153
LEU A 119
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
None
1.43A 1rj6A-3hpaA:
undetectable
1rj6A-3hpaA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJO_A_CUA701_0
(PHENYLETHYLAMINE
OXIDASE)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.39A 1rjoA-3hpaA:
undetectable
1rjoA-3hpaA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.37A 1rkyA-3hpaA:
undetectable
1rkyA-3hpaA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.21A 1utdA-3hpaA:
undetectable
1utdB-3hpaA:
undetectable
1utdA-3hpaA:
10.65
1utdB-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 8 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.21A 1utdB-3hpaA:
undetectable
1utdC-3hpaA:
undetectable
1utdB-3hpaA:
10.65
1utdC-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 1utdC-3hpaA:
undetectable
1utdD-3hpaA:
undetectable
1utdC-3hpaA:
10.65
1utdD-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 1utdD-3hpaA:
undetectable
1utdE-3hpaA:
undetectable
1utdD-3hpaA:
10.65
1utdE-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 8 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 1utdF-3hpaA:
undetectable
1utdG-3hpaA:
undetectable
1utdF-3hpaA:
10.65
1utdG-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 1utdG-3hpaA:
undetectable
1utdH-3hpaA:
undetectable
1utdG-3hpaA:
10.65
1utdH-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 8 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.18A 1utdJ-3hpaA:
undetectable
1utdK-3hpaA:
undetectable
1utdJ-3hpaA:
10.65
1utdK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.18A 1utdN-3hpaA:
undetectable
1utdO-3hpaA:
undetectable
1utdN-3hpaA:
10.65
1utdO-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.23A 1utdR-3hpaA:
undetectable
1utdS-3hpaA:
undetectable
1utdR-3hpaA:
10.65
1utdS-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.68A 1v54A-3hpaA:
undetectable
1v54A-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.70A 1v54N-3hpaA:
undetectable
1v54N-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.69A 1v55A-3hpaA:
undetectable
1v55A-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.69A 1v55N-3hpaA:
undetectable
1v55N-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.47A 1w2zA-3hpaA:
undetectable
1w2zA-3hpaA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.42A 1w2zB-3hpaA:
undetectable
1w2zB-3hpaA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.41A 1w2zC-3hpaA:
undetectable
1w2zC-3hpaA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.38A 1w2zD-3hpaA:
undetectable
1w2zD-3hpaA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.68A 2dyrA-3hpaA:
undetectable
2dyrA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.70A 2dyrN-3hpaA:
undetectable
2dyrN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.69A 2dysA-3hpaA:
undetectable
2dysA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.70A 2dysN-3hpaA:
undetectable
2dysN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.67A 2eijA-3hpaA:
undetectable
2eijA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.69A 2eijN-3hpaA:
0.1
2eijN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.66A 2eikA-3hpaA:
undetectable
2eikA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.70A 2eikN-3hpaA:
undetectable
2eikN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.68A 2eilA-3hpaA:
undetectable
2eilA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.72A 2eilN-3hpaA:
undetectable
2eilN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.71A 2eimA-3hpaA:
undetectable
2eimA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.70A 2eimN-3hpaA:
undetectable
2eimN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.68A 2einA-3hpaA:
undetectable
2einA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.70A 2einN-3hpaA:
0.4
2einN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 8 GLY A 182
ARG A 181
THR A 209
ILE A 205
None
0.96A 2f9wA-3hpaA:
undetectable
2f9wB-3hpaA:
undetectable
2f9wA-3hpaA:
24.39
2f9wB-3hpaA:
24.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.43A 2oqeA-3hpaA:
undetectable
2oqeA-3hpaA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.44A 2oqeB-3hpaA:
undetectable
2oqeB-3hpaA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_C_CUC801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.42A 2oqeC-3hpaA:
undetectable
2oqeC-3hpaA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_D_CUD801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.42A 2oqeD-3hpaA:
undetectable
2oqeD-3hpaA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_F_CUF801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.43A 2oqeF-3hpaA:
undetectable
2oqeF-3hpaA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
6 / 12 HIS A  93
HIS A  95
HIS A 259
GLU A 262
HIS A 296
ASP A 347
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
None
ZN  A 480 ( 4.8A)
ZN  A 480 (-3.2A)
0.86A 2pgrA-3hpaA:
22.7
2pgrA-3hpaA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 VAL A 428
ASP A 426
GLU A  48
None
0.74A 2qeuA-3hpaA:
undetectable
2qeuA-3hpaA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.35A 2w0qA-3hpaA:
undetectable
2w0qA-3hpaA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.38A 2w0qB-3hpaA:
undetectable
2w0qB-3hpaA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.75A 2y69A-3hpaA:
undetectable
2y69A-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_2
(ADENOSYLHOMOCYSTEINA
SE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 LEU A 474
GLN A  98
THR A 101
THR A 127
None
1.48A 2zj0D-3hpaA:
undetectable
2zj0D-3hpaA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.77A 2zxwN-3hpaA:
undetectable
2zxwN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.74A 3abkA-3hpaA:
undetectable
3abkA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.75A 3ablA-3hpaA:
undetectable
3ablA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.77A 3ablN-3hpaA:
undetectable
3ablN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.76A 3abmA-3hpaA:
undetectable
3abmA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.76A 3abmN-3hpaA:
undetectable
3abmN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.74A 3ag1A-3hpaA:
undetectable
3ag1A-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.76A 3ag1N-3hpaA:
undetectable
3ag1N-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.73A 3ag2A-3hpaA:
undetectable
3ag2A-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.73A 3ag2N-3hpaA:
undetectable
3ag2N-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.73A 3ag3A-3hpaA:
undetectable
3ag3A-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.76A 3ag3N-3hpaA:
undetectable
3ag3N-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.70A 3ag4A-3hpaA:
undetectable
3ag4A-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.71A 3ag4N-3hpaA:
undetectable
3ag4N-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.73A 3asnA-3hpaA:
undetectable
3asnA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.73A 3asoA-3hpaA:
undetectable
3asoA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.74A 3asoN-3hpaA:
undetectable
3asoN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 GLU A 262
HIS A 294
HIS A 257
None
0.91A 3co4A-3hpaA:
5.9
3co4A-3hpaA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 5 ALA A 412
LEU A  39
GLY A  53
THR A  30
None
0.94A 3dl9A-3hpaA:
undetectable
3dl9A-3hpaA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.75A 3dtuA-3hpaA:
undetectable
3dtuA-3hpaA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.74A 3dtuC-3hpaA:
undetectable
3dtuC-3hpaA:
23.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)
3hpa AMIDOHYDROLASE
(unidentified)
6 / 10 LEU A 402
ALA A 408
VAL A  62
LEU A  78
VAL A  64
ILE A  61
None
1.24A 3em3A-3hpaA:
undetectable
3em3A-3hpaA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_CUA801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.43A 3hiiA-3hpaA:
undetectable
3hiiA-3hpaA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_CUB801_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A  95
HIS A  93
HIS A 153
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.42A 3hiiB-3hpaA:
undetectable
3hiiB-3hpaA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 8 ASP A 152
LEU A 126
PRO A 158
TRP A 123
None
1.21A 3jq7B-3hpaA:
undetectable
3jq7B-3hpaA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 GLY A 400
LEU A 394
SER A 150
GLU A 384
ALA A 386
None
1.12A 3kkzA-3hpaA:
undetectable
3kkzA-3hpaA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 5 HIS A  94
HIS A 296
HIS A  93
HIS A 259
None
ZN  A 480 ( 4.8A)
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
1.14A 3likA-3hpaA:
undetectable
3likA-3hpaA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 6 GLY A 354
VAL A 346
HIS A  94
SER A 349
None
1.10A 3tj7A-3hpaA:
undetectable
3tj7B-3hpaA:
undetectable
3tj7A-3hpaA:
16.67
3tj7B-3hpaA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 6 GLY A 354
VAL A 346
HIS A  94
SER A 349
None
1.05A 3tj7C-3hpaA:
undetectable
3tj7D-3hpaA:
undetectable
3tj7C-3hpaA:
16.67
3tj7D-3hpaA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 6 VAL A 346
HIS A  94
SER A 349
GLY A 354
None
1.07A 3tj7C-3hpaA:
undetectable
3tj7D-3hpaA:
undetectable
3tj7C-3hpaA:
16.67
3tj7D-3hpaA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 VAL A 227
LEU A 256
ALA A 183
LEU A 241
VAL A 237
None
1.11A 3w67C-3hpaA:
undetectable
3w67C-3hpaA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 8 GLN A  98
HIS A  95
HIS A  93
HIS A 153
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
None
0.96A 3w6hA-3hpaA:
undetectable
3w6hA-3hpaA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.73A 3wg7A-3hpaA:
undetectable
3wg7A-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.74A 3wg7N-3hpaA:
undetectable
3wg7N-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.74A 3x2qA-3hpaA:
undetectable
3x2qA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.72A 3x2qN-3hpaA:
0.3
3x2qN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 5 LEU A 116
HIS A 259
GLU A 262
HIS A 296
None
ZN  A 480 (-3.5A)
None
ZN  A 480 ( 4.8A)
1.22A 4a7bB-3hpaA:
undetectable
4a7bB-3hpaA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 GLN A  98
HIS A 259
HIS A 296
SER A 321
ASP A 347
None
ZN  A 480 (-3.5A)
ZN  A 480 ( 4.8A)
None
ZN  A 480 (-3.2A)
0.40A 4aqlA-3hpaA:
43.1
4aqlA-3hpaA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
6 / 12 GLN A  98
LEU A 112
LEU A 116
HIS A 259
GLU A 262
HIS A 296
None
None
None
ZN  A 480 (-3.5A)
None
ZN  A 480 ( 4.8A)
1.13A 4aqlA-3hpaA:
43.1
4aqlA-3hpaA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 GLN A  98
LEU A 116
HIS A 259
HIS A 296
SER A 321
None
None
ZN  A 480 (-3.5A)
ZN  A 480 ( 4.8A)
None
0.76A 4aqlA-3hpaA:
43.1
4aqlA-3hpaA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 LEU A 112
HIS A 259
HIS A 296
SER A 321
ASP A 347
None
ZN  A 480 (-3.5A)
ZN  A 480 ( 4.8A)
None
ZN  A 480 (-3.2A)
1.10A 4aqlA-3hpaA:
43.1
4aqlA-3hpaA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 TRP A 115
TRP A 123
THR A 101
None
1.49A 4bboB-3hpaA:
undetectable
4bboB-3hpaA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 6 TYR A  97
HIS A  93
HIS A 259
TYR A 120
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
None
1.49A 4df2A-3hpaA:
6.5
4df2A-3hpaA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 6 TYR A  97
HIS A 153
HIS A 259
TYR A 155
None
None
ZN  A 480 (-3.5A)
None
1.37A 4df2A-3hpaA:
6.5
4df2A-3hpaA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF2_A_4CHA506_0
(NADPH DEHYDROGENASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 6 TYR A 120
HIS A  95
HIS A 259
TYR A 155
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
None
1.25A 4df2A-3hpaA:
6.5
4df2A-3hpaA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 PHE A 308
VAL A 288
GLU A 283
None
0.64A 4fvqA-3hpaA:
undetectable
4fvqA-3hpaA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 LEU A 142
MET A 357
VAL A 358
THR A 442
MET A 175
None
1.27A 4ojbA-3hpaA:
undetectable
4ojbA-3hpaA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 LEU A 142
MET A 357
VAL A 358
THR A 442
MET A 175
None
1.26A 4okxA-3hpaA:
undetectable
4okxA-3hpaA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 LEU A 142
MET A 357
VAL A 358
THR A 442
MET A 175
None
1.26A 4olmA-3hpaA:
undetectable
4olmA-3hpaA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 7 ARG A 176
THR A 148
GLY A  88
THR A 149
None
0.99A 4qwpB-3hpaA:
undetectable
4qwpB-3hpaA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_B_AERB601_1
(CYP17A1 PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 7 GLY A 354
ALA A 355
GLU A 360
SER A 150
None
0.80A 4r1zB-3hpaA:
undetectable
4r1zB-3hpaA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
6 / 12 HIS A  95
LEU A 112
HIS A 259
HIS A 296
LEU A 325
ASP A 347
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.5A)
ZN  A 480 ( 4.8A)
None
ZN  A 480 (-3.2A)
0.71A 4r88A-3hpaA:
34.0
4r88A-3hpaA:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 HIS A  95
LEU A 112
HIS A 259
LEU A 325
ASP A 347
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.5A)
None
ZN  A 480 (-3.2A)
0.73A 4r88B-3hpaA:
34.8
4r88B-3hpaA:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 HIS A  95
LEU A 112
HIS A 259
LEU A 325
ASP A 347
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.5A)
None
ZN  A 480 (-3.2A)
0.75A 4r88C-3hpaA:
34.2
4r88C-3hpaA:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 HIS A  95
LEU A 112
HIS A 259
LEU A 325
ASP A 347
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.5A)
None
ZN  A 480 (-3.2A)
0.70A 4r88D-3hpaA:
34.3
4r88D-3hpaA:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 HIS A  95
LEU A 112
HIS A 259
LEU A 325
ASP A 347
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.5A)
None
ZN  A 480 (-3.2A)
0.70A 4r88E-3hpaA:
34.0
4r88E-3hpaA:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 HIS A  95
LEU A 112
HIS A 259
LEU A 325
ASP A 347
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.5A)
None
ZN  A 480 (-3.2A)
0.73A 4r88F-3hpaA:
34.3
4r88F-3hpaA:
25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 ARG A 207
ASP A 208
ARG A 211
None
0.55A 4wq4B-3hpaA:
undetectable
4wq4B-3hpaA:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.72A 5b1aA-3hpaA:
undetectable
5b1aA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.74A 5b1aN-3hpaA:
undetectable
5b1aN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.71A 5b1bA-3hpaA:
undetectable
5b1bA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.71A 5b1bN-3hpaA:
undetectable
5b1bN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.69A 5b3sA-3hpaA:
undetectable
5b3sA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.71A 5b3sN-3hpaA:
0.0
5b3sN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.23A 5eeuA-3hpaA:
undetectable
5eeuB-3hpaA:
undetectable
5eeuA-3hpaA:
10.65
5eeuB-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eeuB-3hpaA:
undetectable
5eeuC-3hpaA:
undetectable
5eeuB-3hpaA:
10.65
5eeuC-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5eeuC-3hpaA:
undetectable
5eeuD-3hpaA:
undetectable
5eeuC-3hpaA:
10.65
5eeuD-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.22A 5eeuD-3hpaA:
undetectable
5eeuE-3hpaA:
undetectable
5eeuD-3hpaA:
10.65
5eeuE-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.22A 5eeuE-3hpaA:
undetectable
5eeuF-3hpaA:
undetectable
5eeuE-3hpaA:
10.65
5eeuF-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5eeuF-3hpaA:
undetectable
5eeuG-3hpaA:
undetectable
5eeuF-3hpaA:
10.65
5eeuG-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eeuG-3hpaA:
undetectable
5eeuH-3hpaA:
undetectable
5eeuG-3hpaA:
10.65
5eeuH-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 5eeuH-3hpaA:
undetectable
5eeuI-3hpaA:
undetectable
5eeuH-3hpaA:
10.65
5eeuI-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.22A 5eeuJ-3hpaA:
undetectable
5eeuK-3hpaA:
undetectable
5eeuJ-3hpaA:
10.65
5eeuK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.19A 5eeuA-3hpaA:
undetectable
5eeuK-3hpaA:
undetectable
5eeuA-3hpaA:
10.65
5eeuK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.24A 5eeuN-3hpaA:
undetectable
5eeuO-3hpaA:
undetectable
5eeuN-3hpaA:
10.65
5eeuO-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eeuP-3hpaA:
undetectable
5eeuQ-3hpaA:
undetectable
5eeuP-3hpaA:
10.65
5eeuQ-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eeuR-3hpaA:
undetectable
5eeuS-3hpaA:
undetectable
5eeuR-3hpaA:
10.65
5eeuS-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eeuS-3hpaA:
undetectable
5eeuT-3hpaA:
undetectable
5eeuS-3hpaA:
10.65
5eeuT-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eeuT-3hpaA:
undetectable
5eeuU-3hpaA:
undetectable
5eeuT-3hpaA:
10.65
5eeuU-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.21A 5eeuU-3hpaA:
undetectable
5eeuV-3hpaA:
undetectable
5eeuU-3hpaA:
10.65
5eeuV-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eevB-3hpaA:
undetectable
5eevC-3hpaA:
undetectable
5eevB-3hpaA:
10.65
5eevC-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5eevC-3hpaA:
undetectable
5eevD-3hpaA:
undetectable
5eevC-3hpaA:
10.65
5eevD-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 5eevD-3hpaA:
undetectable
5eevE-3hpaA:
undetectable
5eevD-3hpaA:
10.65
5eevE-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.22A 5eevE-3hpaA:
undetectable
5eevF-3hpaA:
undetectable
5eevE-3hpaA:
10.65
5eevF-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eevG-3hpaA:
undetectable
5eevH-3hpaA:
undetectable
5eevG-3hpaA:
10.65
5eevH-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 5eevH-3hpaA:
undetectable
5eevI-3hpaA:
undetectable
5eevH-3hpaA:
10.65
5eevI-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.23A 5eevJ-3hpaA:
undetectable
5eevK-3hpaA:
undetectable
5eevJ-3hpaA:
10.65
5eevK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.19A 5eevA-3hpaA:
undetectable
5eevK-3hpaA:
undetectable
5eevA-3hpaA:
10.65
5eevK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.24A 5eevN-3hpaA:
undetectable
5eevO-3hpaA:
undetectable
5eevN-3hpaA:
10.65
5eevO-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eevO-3hpaA:
undetectable
5eevP-3hpaA:
undetectable
5eevO-3hpaA:
10.65
5eevP-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eevP-3hpaA:
undetectable
5eevQ-3hpaA:
undetectable
5eevP-3hpaA:
10.65
5eevQ-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eevR-3hpaA:
undetectable
5eevS-3hpaA:
undetectable
5eevR-3hpaA:
10.65
5eevS-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eevS-3hpaA:
undetectable
5eevT-3hpaA:
undetectable
5eevS-3hpaA:
10.65
5eevT-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eevT-3hpaA:
undetectable
5eevU-3hpaA:
undetectable
5eevT-3hpaA:
10.65
5eevU-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eevU-3hpaA:
undetectable
5eevV-3hpaA:
undetectable
5eevU-3hpaA:
10.65
5eevV-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eewB-3hpaA:
undetectable
5eewC-3hpaA:
undetectable
5eewB-3hpaA:
10.65
5eewC-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5eewC-3hpaA:
undetectable
5eewD-3hpaA:
undetectable
5eewC-3hpaA:
10.65
5eewD-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 5eewD-3hpaA:
undetectable
5eewE-3hpaA:
undetectable
5eewD-3hpaA:
10.65
5eewE-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.22A 5eewE-3hpaA:
undetectable
5eewF-3hpaA:
undetectable
5eewE-3hpaA:
10.65
5eewF-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eewF-3hpaA:
undetectable
5eewG-3hpaA:
undetectable
5eewF-3hpaA:
10.65
5eewG-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eewG-3hpaA:
undetectable
5eewH-3hpaA:
undetectable
5eewG-3hpaA:
10.65
5eewH-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5eewH-3hpaA:
undetectable
5eewI-3hpaA:
undetectable
5eewH-3hpaA:
10.65
5eewI-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.23A 5eewJ-3hpaA:
undetectable
5eewK-3hpaA:
undetectable
5eewJ-3hpaA:
10.65
5eewK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.19A 5eewA-3hpaA:
undetectable
5eewK-3hpaA:
undetectable
5eewA-3hpaA:
10.65
5eewK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.24A 5eewN-3hpaA:
undetectable
5eewO-3hpaA:
undetectable
5eewN-3hpaA:
10.65
5eewO-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eewO-3hpaA:
undetectable
5eewP-3hpaA:
undetectable
5eewO-3hpaA:
10.65
5eewP-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eewP-3hpaA:
undetectable
5eewQ-3hpaA:
undetectable
5eewP-3hpaA:
10.65
5eewQ-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eewR-3hpaA:
undetectable
5eewS-3hpaA:
undetectable
5eewR-3hpaA:
10.65
5eewS-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eewS-3hpaA:
undetectable
5eewT-3hpaA:
undetectable
5eewS-3hpaA:
10.65
5eewT-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eewT-3hpaA:
undetectable
5eewU-3hpaA:
undetectable
5eewT-3hpaA:
10.65
5eewU-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.21A 5eewU-3hpaA:
undetectable
5eewV-3hpaA:
undetectable
5eewU-3hpaA:
10.65
5eewV-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eexB-3hpaA:
undetectable
5eexC-3hpaA:
undetectable
5eexB-3hpaA:
10.65
5eexC-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5eexC-3hpaA:
undetectable
5eexD-3hpaA:
undetectable
5eexC-3hpaA:
10.65
5eexD-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 5eexD-3hpaA:
undetectable
5eexE-3hpaA:
undetectable
5eexD-3hpaA:
10.65
5eexE-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 5eexE-3hpaA:
undetectable
5eexF-3hpaA:
undetectable
5eexE-3hpaA:
10.65
5eexF-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eexF-3hpaA:
undetectable
5eexG-3hpaA:
undetectable
5eexF-3hpaA:
10.65
5eexG-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eexG-3hpaA:
undetectable
5eexH-3hpaA:
undetectable
5eexG-3hpaA:
10.65
5eexH-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5eexH-3hpaA:
undetectable
5eexI-3hpaA:
undetectable
5eexH-3hpaA:
10.65
5eexI-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 11 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eexI-3hpaA:
undetectable
5eexJ-3hpaA:
undetectable
5eexI-3hpaA:
10.65
5eexJ-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.22A 5eexJ-3hpaA:
undetectable
5eexK-3hpaA:
undetectable
5eexJ-3hpaA:
10.65
5eexK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.19A 5eexA-3hpaA:
undetectable
5eexK-3hpaA:
undetectable
5eexA-3hpaA:
10.65
5eexK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.24A 5eexN-3hpaA:
undetectable
5eexO-3hpaA:
undetectable
5eexN-3hpaA:
10.65
5eexO-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eexO-3hpaA:
undetectable
5eexP-3hpaA:
undetectable
5eexO-3hpaA:
10.65
5eexP-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eexP-3hpaA:
undetectable
5eexQ-3hpaA:
undetectable
5eexP-3hpaA:
10.65
5eexQ-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eexQ-3hpaA:
undetectable
5eexR-3hpaA:
undetectable
5eexQ-3hpaA:
10.65
5eexR-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eexR-3hpaA:
undetectable
5eexS-3hpaA:
undetectable
5eexR-3hpaA:
10.65
5eexS-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eexS-3hpaA:
undetectable
5eexT-3hpaA:
undetectable
5eexS-3hpaA:
10.65
5eexT-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eexT-3hpaA:
undetectable
5eexU-3hpaA:
undetectable
5eexT-3hpaA:
10.65
5eexU-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.21A 5eexU-3hpaA:
undetectable
5eexV-3hpaA:
undetectable
5eexU-3hpaA:
10.65
5eexV-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eeyB-3hpaA:
undetectable
5eeyC-3hpaA:
undetectable
5eeyB-3hpaA:
10.65
5eeyC-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5eeyC-3hpaA:
undetectable
5eeyD-3hpaA:
undetectable
5eeyC-3hpaA:
10.65
5eeyD-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 5eeyE-3hpaA:
undetectable
5eeyF-3hpaA:
undetectable
5eeyE-3hpaA:
10.65
5eeyF-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eeyF-3hpaA:
undetectable
5eeyG-3hpaA:
undetectable
5eeyF-3hpaA:
10.65
5eeyG-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.18A 5eeyG-3hpaA:
undetectable
5eeyH-3hpaA:
undetectable
5eeyG-3hpaA:
10.65
5eeyH-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5eeyH-3hpaA:
undetectable
5eeyI-3hpaA:
undetectable
5eeyH-3hpaA:
10.65
5eeyI-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 11 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eeyI-3hpaA:
undetectable
5eeyJ-3hpaA:
undetectable
5eeyI-3hpaA:
10.65
5eeyJ-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.22A 5eeyJ-3hpaA:
undetectable
5eeyK-3hpaA:
undetectable
5eeyJ-3hpaA:
10.65
5eeyK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.19A 5eeyA-3hpaA:
undetectable
5eeyK-3hpaA:
undetectable
5eeyA-3hpaA:
10.65
5eeyK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.24A 5eeyN-3hpaA:
undetectable
5eeyO-3hpaA:
undetectable
5eeyN-3hpaA:
10.65
5eeyO-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eeyO-3hpaA:
undetectable
5eeyP-3hpaA:
undetectable
5eeyO-3hpaA:
10.65
5eeyP-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eeyP-3hpaA:
undetectable
5eeyQ-3hpaA:
undetectable
5eeyP-3hpaA:
10.65
5eeyQ-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eeyQ-3hpaA:
undetectable
5eeyR-3hpaA:
undetectable
5eeyQ-3hpaA:
10.65
5eeyR-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eeyR-3hpaA:
undetectable
5eeyS-3hpaA:
undetectable
5eeyR-3hpaA:
10.65
5eeyS-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eeyS-3hpaA:
undetectable
5eeyT-3hpaA:
undetectable
5eeyS-3hpaA:
10.65
5eeyT-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eeyT-3hpaA:
undetectable
5eeyU-3hpaA:
undetectable
5eeyT-3hpaA:
10.65
5eeyU-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eeyU-3hpaA:
undetectable
5eeyV-3hpaA:
undetectable
5eeyU-3hpaA:
10.65
5eeyV-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.18A 5eezB-3hpaA:
undetectable
5eezC-3hpaA:
undetectable
5eezB-3hpaA:
10.65
5eezC-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5eezC-3hpaA:
undetectable
5eezD-3hpaA:
undetectable
5eezC-3hpaA:
10.65
5eezD-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 5eezD-3hpaA:
undetectable
5eezE-3hpaA:
undetectable
5eezD-3hpaA:
10.65
5eezE-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 5eezE-3hpaA:
undetectable
5eezF-3hpaA:
undetectable
5eezE-3hpaA:
10.65
5eezF-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eezF-3hpaA:
undetectable
5eezG-3hpaA:
undetectable
5eezF-3hpaA:
10.65
5eezG-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eezG-3hpaA:
undetectable
5eezH-3hpaA:
undetectable
5eezG-3hpaA:
10.65
5eezH-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 5eezH-3hpaA:
undetectable
5eezI-3hpaA:
undetectable
5eezH-3hpaA:
10.65
5eezI-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 11 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5eezI-3hpaA:
undetectable
5eezJ-3hpaA:
undetectable
5eezI-3hpaA:
10.65
5eezJ-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.22A 5eezJ-3hpaA:
undetectable
5eezK-3hpaA:
undetectable
5eezJ-3hpaA:
10.65
5eezK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.19A 5eezA-3hpaA:
undetectable
5eezK-3hpaA:
undetectable
5eezA-3hpaA:
10.65
5eezK-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.24A 5eezN-3hpaA:
undetectable
5eezO-3hpaA:
undetectable
5eezN-3hpaA:
10.65
5eezO-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eezO-3hpaA:
undetectable
5eezP-3hpaA:
undetectable
5eezO-3hpaA:
10.65
5eezP-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eezP-3hpaA:
undetectable
5eezQ-3hpaA:
undetectable
5eezP-3hpaA:
10.65
5eezQ-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eezQ-3hpaA:
undetectable
5eezR-3hpaA:
undetectable
5eezQ-3hpaA:
10.65
5eezR-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eezR-3hpaA:
undetectable
5eezS-3hpaA:
undetectable
5eezR-3hpaA:
10.65
5eezS-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eezS-3hpaA:
undetectable
5eezT-3hpaA:
undetectable
5eezS-3hpaA:
10.65
5eezT-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5eezT-3hpaA:
undetectable
5eezU-3hpaA:
undetectable
5eezT-3hpaA:
10.65
5eezU-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5eezU-3hpaA:
undetectable
5eezV-3hpaA:
undetectable
5eezU-3hpaA:
10.65
5eezV-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.18A 5ef0B-3hpaA:
undetectable
5ef0C-3hpaA:
undetectable
5ef0B-3hpaA:
10.65
5ef0C-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5ef0C-3hpaA:
undetectable
5ef0D-3hpaA:
undetectable
5ef0C-3hpaA:
10.65
5ef0D-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 5ef0E-3hpaA:
undetectable
5ef0F-3hpaA:
undetectable
5ef0E-3hpaA:
10.65
5ef0F-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5ef0F-3hpaA:
undetectable
5ef0G-3hpaA:
undetectable
5ef0F-3hpaA:
10.65
5ef0G-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.18A 5ef0G-3hpaA:
undetectable
5ef0H-3hpaA:
undetectable
5ef0G-3hpaA:
10.65
5ef0H-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5ef0H-3hpaA:
undetectable
5ef0I-3hpaA:
undetectable
5ef0H-3hpaA:
10.65
5ef0I-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 11 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5ef0I-3hpaA:
undetectable
5ef0J-3hpaA:
undetectable
5ef0I-3hpaA:
10.65
5ef0J-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.22A 5ef0J-3hpaA:
undetectable
5ef0K-3hpaA:
undetectable
5ef0J-3hpaA:
10.65
5ef0K-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.19A 5ef0A-3hpaA:
undetectable
5ef0K-3hpaA:
undetectable
5ef0A-3hpaA:
10.65
5ef0K-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.23A 5ef0N-3hpaA:
undetectable
5ef0O-3hpaA:
undetectable
5ef0N-3hpaA:
10.65
5ef0O-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef0O-3hpaA:
undetectable
5ef0P-3hpaA:
undetectable
5ef0O-3hpaA:
10.65
5ef0P-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef0P-3hpaA:
undetectable
5ef0Q-3hpaA:
undetectable
5ef0P-3hpaA:
10.65
5ef0Q-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5ef0Q-3hpaA:
undetectable
5ef0R-3hpaA:
undetectable
5ef0Q-3hpaA:
10.65
5ef0R-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5ef0R-3hpaA:
undetectable
5ef0S-3hpaA:
undetectable
5ef0R-3hpaA:
10.65
5ef0S-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef0S-3hpaA:
undetectable
5ef0T-3hpaA:
undetectable
5ef0S-3hpaA:
10.65
5ef0T-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef0U-3hpaA:
undetectable
5ef0V-3hpaA:
undetectable
5ef0U-3hpaA:
10.65
5ef0V-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.18A 5ef1B-3hpaA:
undetectable
5ef1C-3hpaA:
undetectable
5ef1B-3hpaA:
10.65
5ef1C-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5ef1C-3hpaA:
undetectable
5ef1D-3hpaA:
undetectable
5ef1C-3hpaA:
10.65
5ef1D-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 5ef1E-3hpaA:
undetectable
5ef1F-3hpaA:
undetectable
5ef1E-3hpaA:
10.65
5ef1F-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5ef1F-3hpaA:
undetectable
5ef1G-3hpaA:
undetectable
5ef1F-3hpaA:
10.65
5ef1G-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.18A 5ef1G-3hpaA:
undetectable
5ef1H-3hpaA:
undetectable
5ef1G-3hpaA:
10.65
5ef1H-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5ef1H-3hpaA:
undetectable
5ef1I-3hpaA:
undetectable
5ef1H-3hpaA:
10.65
5ef1I-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 11 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5ef1I-3hpaA:
undetectable
5ef1J-3hpaA:
undetectable
5ef1I-3hpaA:
10.65
5ef1J-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.22A 5ef1J-3hpaA:
undetectable
5ef1K-3hpaA:
undetectable
5ef1J-3hpaA:
10.65
5ef1K-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.18A 5ef1A-3hpaA:
undetectable
5ef1K-3hpaA:
undetectable
5ef1A-3hpaA:
10.65
5ef1K-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.23A 5ef1N-3hpaA:
undetectable
5ef1O-3hpaA:
undetectable
5ef1N-3hpaA:
10.65
5ef1O-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef1O-3hpaA:
undetectable
5ef1P-3hpaA:
undetectable
5ef1O-3hpaA:
10.65
5ef1P-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef1P-3hpaA:
undetectable
5ef1Q-3hpaA:
undetectable
5ef1P-3hpaA:
10.65
5ef1Q-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5ef1Q-3hpaA:
undetectable
5ef1R-3hpaA:
undetectable
5ef1Q-3hpaA:
10.65
5ef1R-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5ef1R-3hpaA:
undetectable
5ef1S-3hpaA:
undetectable
5ef1R-3hpaA:
10.65
5ef1S-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef1S-3hpaA:
undetectable
5ef1T-3hpaA:
undetectable
5ef1S-3hpaA:
10.65
5ef1T-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.21A 5ef1T-3hpaA:
undetectable
5ef1U-3hpaA:
undetectable
5ef1T-3hpaA:
10.65
5ef1U-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef1U-3hpaA:
undetectable
5ef1V-3hpaA:
undetectable
5ef1U-3hpaA:
10.65
5ef1V-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.18A 5ef2B-3hpaA:
undetectable
5ef2C-3hpaA:
undetectable
5ef2B-3hpaA:
10.65
5ef2C-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5ef2C-3hpaA:
undetectable
5ef2D-3hpaA:
undetectable
5ef2C-3hpaA:
10.65
5ef2D-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 5ef2E-3hpaA:
undetectable
5ef2F-3hpaA:
undetectable
5ef2E-3hpaA:
10.65
5ef2F-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5ef2F-3hpaA:
undetectable
5ef2G-3hpaA:
undetectable
5ef2F-3hpaA:
10.65
5ef2G-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.18A 5ef2G-3hpaA:
undetectable
5ef2H-3hpaA:
undetectable
5ef2G-3hpaA:
10.65
5ef2H-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5ef2H-3hpaA:
undetectable
5ef2I-3hpaA:
undetectable
5ef2H-3hpaA:
10.65
5ef2I-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 11 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5ef2I-3hpaA:
undetectable
5ef2J-3hpaA:
undetectable
5ef2I-3hpaA:
10.65
5ef2J-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.22A 5ef2J-3hpaA:
undetectable
5ef2K-3hpaA:
undetectable
5ef2J-3hpaA:
10.65
5ef2K-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.19A 5ef2A-3hpaA:
undetectable
5ef2K-3hpaA:
undetectable
5ef2A-3hpaA:
10.65
5ef2K-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.23A 5ef2N-3hpaA:
undetectable
5ef2O-3hpaA:
undetectable
5ef2N-3hpaA:
10.65
5ef2O-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef2O-3hpaA:
undetectable
5ef2P-3hpaA:
undetectable
5ef2O-3hpaA:
10.65
5ef2P-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef2P-3hpaA:
undetectable
5ef2Q-3hpaA:
undetectable
5ef2P-3hpaA:
10.65
5ef2Q-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5ef2Q-3hpaA:
undetectable
5ef2R-3hpaA:
undetectable
5ef2Q-3hpaA:
10.65
5ef2R-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5ef2R-3hpaA:
undetectable
5ef2S-3hpaA:
undetectable
5ef2R-3hpaA:
10.65
5ef2S-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef2S-3hpaA:
undetectable
5ef2T-3hpaA:
undetectable
5ef2S-3hpaA:
10.65
5ef2T-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5ef2T-3hpaA:
undetectable
5ef2U-3hpaA:
undetectable
5ef2T-3hpaA:
10.65
5ef2U-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef2U-3hpaA:
undetectable
5ef2V-3hpaA:
undetectable
5ef2U-3hpaA:
10.65
5ef2V-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.18A 5ef3B-3hpaA:
undetectable
5ef3C-3hpaA:
undetectable
5ef3B-3hpaA:
10.65
5ef3C-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5ef3C-3hpaA:
undetectable
5ef3D-3hpaA:
undetectable
5ef3C-3hpaA:
10.65
5ef3D-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.21A 5ef3E-3hpaA:
undetectable
5ef3F-3hpaA:
undetectable
5ef3E-3hpaA:
10.65
5ef3F-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_F_TRPF101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5ef3F-3hpaA:
undetectable
5ef3G-3hpaA:
undetectable
5ef3F-3hpaA:
10.65
5ef3G-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.18A 5ef3G-3hpaA:
undetectable
5ef3H-3hpaA:
undetectable
5ef3G-3hpaA:
10.65
5ef3H-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.20A 5ef3H-3hpaA:
undetectable
5ef3I-3hpaA:
undetectable
5ef3H-3hpaA:
10.65
5ef3I-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 11 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.19A 5ef3I-3hpaA:
undetectable
5ef3J-3hpaA:
undetectable
5ef3I-3hpaA:
10.65
5ef3J-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 THR A 442
GLY A 174
ALA A 140
THR A 457
ILE A 173
None
1.22A 5ef3J-3hpaA:
undetectable
5ef3K-3hpaA:
undetectable
5ef3J-3hpaA:
10.65
5ef3K-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.18A 5ef3A-3hpaA:
undetectable
5ef3K-3hpaA:
undetectable
5ef3A-3hpaA:
10.65
5ef3K-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.24A 5ef3N-3hpaA:
undetectable
5ef3O-3hpaA:
undetectable
5ef3N-3hpaA:
10.65
5ef3O-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef3O-3hpaA:
undetectable
5ef3P-3hpaA:
undetectable
5ef3O-3hpaA:
10.65
5ef3P-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef3P-3hpaA:
undetectable
5ef3Q-3hpaA:
undetectable
5ef3P-3hpaA:
10.65
5ef3Q-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5ef3Q-3hpaA:
undetectable
5ef3R-3hpaA:
undetectable
5ef3Q-3hpaA:
10.65
5ef3R-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.22A 5ef3R-3hpaA:
undetectable
5ef3S-3hpaA:
undetectable
5ef3R-3hpaA:
10.65
5ef3S-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef3S-3hpaA:
undetectable
5ef3T-3hpaA:
undetectable
5ef3S-3hpaA:
10.65
5ef3T-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 10 GLY A 174
ALA A 140
THR A 457
ILE A 173
THR A 442
None
1.20A 5ef3U-3hpaA:
undetectable
5ef3V-3hpaA:
undetectable
5ef3U-3hpaA:
10.65
5ef3V-3hpaA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EVY_X_SALX502_1
(SALICYLATE
HYDROXYLASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 5 SER A 437
GLN A 417
LEU A 415
PHE A 420
None
1.39A 5evyX-3hpaA:
undetectable
5evyX-3hpaA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 VAL A 393
SER A 151
MET A 224
None
0.82A 5ikqA-3hpaA:
undetectable
5ikqA-3hpaA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.71A 5iy5A-3hpaA:
undetectable
5iy5A-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.71A 5iy5N-3hpaA:
undetectable
5iy5N-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 GLY A  53
ASP A 409
VAL A 443
VAL A  77
LEU A  31
None
1.06A 5kocA-3hpaA:
undetectable
5kocA-3hpaA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A  95
HIS A 257
HIS A  93
HIS A 259
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
0.96A 5mhwA-3hpaA:
undetectable
5mhwA-3hpaA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A  95
HIS A 257
HIS A  93
HIS A 259
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
0.95A 5mhxA-3hpaA:
undetectable
5mhxA-3hpaA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A  95
HIS A 257
HIS A  93
HIS A 259
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
0.95A 5mhyA-3hpaA:
undetectable
5mhyA-3hpaA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A  95
HIS A 257
HIS A  93
HIS A 259
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
0.95A 5mhzA-3hpaA:
undetectable
5mhzA-3hpaA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A  95
HIS A 257
HIS A  93
HIS A 259
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
0.95A 5mi1A-3hpaA:
undetectable
5mi1A-3hpaA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A  95
HIS A 257
HIS A  93
HIS A 259
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
0.95A 5mi2A-3hpaA:
undetectable
5mi2A-3hpaA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A  95
HIS A 257
HIS A  93
HIS A 259
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
0.95A 5miaA-3hpaA:
undetectable
5miaA-3hpaA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A  95
HIS A 257
HIS A  93
HIS A 259
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
0.95A 5mibA-3hpaA:
undetectable
5mibA-3hpaA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A  95
HIS A 257
HIS A  93
HIS A 259
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
0.95A 5micA-3hpaA:
undetectable
5micA-3hpaA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A  95
HIS A 257
HIS A  93
HIS A 259
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
0.96A 5midA-3hpaA:
undetectable
5midA-3hpaA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A  95
HIS A 257
HIS A  93
HIS A 259
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
0.95A 5mieA-3hpaA:
undetectable
5mieA-3hpaA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 LEU A 455
THR A 442
THR A 137
GLY A 146
MET A 175
None
1.33A 5utuF-3hpaA:
undetectable
5utuF-3hpaA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.75A 5waua-3hpaA:
undetectable
5waua-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.72A 5x19A-3hpaA:
undetectable
5x19A-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.74A 5xdxA-3hpaA:
undetectable
5xdxA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.74A 5xdxN-3hpaA:
undetectable
5xdxN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.74A 5z84A-3hpaA:
undetectable
5z84A-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.76A 5z84N-3hpaA:
undetectable
5z84N-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.76A 5z85A-3hpaA:
undetectable
5z85A-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.76A 5z85N-3hpaA:
0.6
5z85N-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.74A 5zcoA-3hpaA:
undetectable
5zcoA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.71A 5zcoN-3hpaA:
0.6
5zcoN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.75A 5zcpA-3hpaA:
undetectable
5zcpA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.77A 5zcpN-3hpaA:
undetectable
5zcpN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.74A 5zcqA-3hpaA:
undetectable
5zcqA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.74A 5zcqN-3hpaA:
undetectable
5zcqN-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 5 HIS A 153
HIS A 259
HIS A  93
HIS A  95
None
ZN  A 480 (-3.5A)
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.95A 5zrdB-3hpaA:
undetectable
5zrdB-3hpaA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A  95
HIS A 153
HIS A  93
HIS A 259
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
1.18A 5zrdC-3hpaA:
undetectable
5zrdC-3hpaA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A 153
HIS A 259
HIS A  93
HIS A  95
None
ZN  A 480 (-3.5A)
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.99A 5zrdC-3hpaA:
undetectable
5zrdC-3hpaA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A  95
HIS A 153
HIS A  93
HIS A 259
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
1.15A 5zrdD-3hpaA:
undetectable
5zrdD-3hpaA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 4 HIS A 153
HIS A 259
HIS A  93
HIS A  95
None
ZN  A 480 (-3.5A)
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.98A 5zrdD-3hpaA:
undetectable
5zrdD-3hpaA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)
3hpa AMIDOHYDROLASE
(unidentified)
4 / 7 ARG A 396
ARG A 176
THR A 148
PRO A  87
None
1.44A 6a4iB-3hpaA:
undetectable
6a4iB-3hpaA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 9 VAL A 237
LEU A 256
ALA A 246
VAL A 247
ASP A 244
None
1.28A 6c2mB-3hpaA:
undetectable
6c2mB-3hpaA:
9.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 ARG A 221
ARG A 396
ASP A 398
None
0.85A 6d8pA-3hpaA:
undetectable
6d8pA-3hpaA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 MET A 406
VAL A 449
THR A 387
LEU A 388
ALA A 391
None
1.12A 6djzC-3hpaA:
undetectable
6djzC-3hpaA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_1
(CYTOCHROME P450 1A1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 SER A 349
SER A  99
ALA A 140
None
0.63A 6dwnC-3hpaA:
undetectable
6dwnC-3hpaA:
11.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 HIS A  95
HIS A 259
GLU A 262
HIS A 296
ASP A 347
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
None
ZN  A 480 ( 4.8A)
ZN  A 480 (-3.2A)
0.86A 6n91A-3hpaA:
23.1
6n91A-3hpaA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 HIS A  95
LEU A 112
HIS A 259
HIS A 296
ASP A 347
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.5A)
ZN  A 480 ( 4.8A)
ZN  A 480 (-3.2A)
0.70A 6n91A-3hpaA:
23.1
6n91A-3hpaA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 HIS A  95
HIS A 259
GLU A 262
HIS A 296
ASP A 347
ZN  A 480 (-3.3A)
ZN  A 480 (-3.5A)
None
ZN  A 480 ( 4.8A)
ZN  A 480 (-3.2A)
0.85A 6n91B-3hpaA:
23.2
6n91B-3hpaA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)
3hpa AMIDOHYDROLASE
(unidentified)
5 / 12 HIS A  95
LEU A 112
HIS A 259
HIS A 296
ASP A 347
ZN  A 480 (-3.3A)
None
ZN  A 480 (-3.5A)
ZN  A 480 ( 4.8A)
ZN  A 480 (-3.2A)
0.61A 6n91B-3hpaA:
23.2
6n91B-3hpaA:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.74A 6nknA-3hpaA:
undetectable
6nknA-3hpaA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)
3hpa AMIDOHYDROLASE
(unidentified)
3 / 3 HIS A 153
HIS A  95
HIS A  93
None
ZN  A 480 (-3.3A)
ZN  A 480 (-3.3A)
0.75A 6nknN-3hpaA:
undetectable
6nknN-3hpaA:
22.36