SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hpc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3hpc SNX5 PROTEIN
(Rattus
norvegicus) 		3 / 3 SER X  30
HIS X 153
ASP X  84
 None
 0.82A 2oxtA-3hpcX:
undetectable		 2oxtA-3hpcX:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hpc SNX5 PROTEIN
(Rattus
norvegicus) 		4 / 6 GLN X 148
PHE X 162
LEU X 166
PHE X  63
 None
 1.12A 5b1bC-3hpcX:
undetectable
5b1bJ-3hpcX:
undetectable		 5b1bC-3hpcX:
20.23
5b1bJ-3hpcX:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3hpc SNX5 PROTEIN
(Rattus
norvegicus) 		3 / 3 TYR X 168
ASP X 169
GLN X 170
 None
 0.80A 6g1pA-3hpcX:
undetectable		 6g1pA-3hpcX:
16.29