SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hq2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_B_DVAB6_0
(GRAMICIDIN A)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		3 / 3 TRP A 312
ALA A 338
VAL A 336
 None
 0.95A 1c4dA-3hq2A:
undetectable
1c4dB-3hq2A:
undetectable		 1c4dA-3hq2A:
2.98
1c4dB-3hq2A:
2.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.41A 1c9sA-3hq2A:
undetectable
1c9sK-3hq2A:
undetectable		 1c9sA-3hq2A:
8.96
1c9sK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.41A 1c9sD-3hq2A:
undetectable
1c9sE-3hq2A:
undetectable		 1c9sD-3hq2A:
8.96
1c9sE-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 1c9sE-3hq2A:
undetectable
1c9sF-3hq2A:
undetectable		 1c9sE-3hq2A:
8.96
1c9sF-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.43A 1c9sF-3hq2A:
undetectable
1c9sG-3hq2A:
undetectable		 1c9sF-3hq2A:
8.96
1c9sG-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 1c9sH-3hq2A:
undetectable
1c9sI-3hq2A:
undetectable		 1c9sH-3hq2A:
8.96
1c9sI-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 1c9sJ-3hq2A:
undetectable
1c9sK-3hq2A:
undetectable		 1c9sJ-3hq2A:
8.96
1c9sK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.33A 1c9sL-3hq2A:
undetectable
1c9sM-3hq2A:
undetectable		 1c9sL-3hq2A:
8.96
1c9sM-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.35A 1c9sM-3hq2A:
undetectable
1c9sN-3hq2A:
undetectable		 1c9sM-3hq2A:
8.96
1c9sN-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.34A 1c9sO-3hq2A:
undetectable
1c9sP-3hq2A:
undetectable		 1c9sO-3hq2A:
8.96
1c9sP-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.35A 1c9sS-3hq2A:
undetectable
1c9sT-3hq2A:
undetectable		 1c9sS-3hq2A:
8.96
1c9sT-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.39A 1gtfA-3hq2A:
undetectable
1gtfK-3hq2A:
undetectable		 1gtfA-3hq2A:
8.96
1gtfK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.41A 1gtfA-3hq2A:
undetectable
1gtfB-3hq2A:
undetectable		 1gtfA-3hq2A:
8.96
1gtfB-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 1gtfC-3hq2A:
undetectable
1gtfD-3hq2A:
undetectable		 1gtfC-3hq2A:
8.96
1gtfD-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.38A 1gtfE-3hq2A:
undetectable
1gtfF-3hq2A:
undetectable		 1gtfE-3hq2A:
8.96
1gtfF-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 1gtfF-3hq2A:
undetectable
1gtfG-3hq2A:
undetectable		 1gtfF-3hq2A:
8.96
1gtfG-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.41A 1gtfG-3hq2A:
undetectable
1gtfH-3hq2A:
undetectable		 1gtfG-3hq2A:
8.96
1gtfH-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 1gtfH-3hq2A:
undetectable
1gtfI-3hq2A:
undetectable		 1gtfH-3hq2A:
8.96
1gtfI-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 1gtfI-3hq2A:
undetectable
1gtfJ-3hq2A:
undetectable		 1gtfI-3hq2A:
8.96
1gtfJ-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.33A 1gtfO-3hq2A:
undetectable
1gtfP-3hq2A:
undetectable		 1gtfO-3hq2A:
8.96
1gtfP-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.35A 1gtfP-3hq2A:
undetectable
1gtfQ-3hq2A:
undetectable		 1gtfP-3hq2A:
8.96
1gtfQ-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.33A 1gtfT-3hq2A:
undetectable
1gtfU-3hq2A:
undetectable		 1gtfT-3hq2A:
8.96
1gtfU-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 11 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.35A 1gtfU-3hq2A:
undetectable
1gtfV-3hq2A:
undetectable		 1gtfU-3hq2A:
8.96
1gtfV-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.34A 1gtfL-3hq2A:
undetectable
1gtfV-3hq2A:
undetectable		 1gtfL-3hq2A:
8.96
1gtfV-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.38A 1gtnG-3hq2A:
undetectable
1gtnH-3hq2A:
undetectable		 1gtnG-3hq2A:
8.96
1gtnH-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		7 / 12 HIS A 234
HIS A 265
GLU A 266
HIS A 269
GLU A 295
HIS A 408
TYR A 420
 None
ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
ZN  A 502 ( 3.3A)
ZN  A 502 ( 2.2A)
None
PO4  A 503 (-4.2A)
 0.61A 1j36A-3hq2A:
22.9		 1j36A-3hq2A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		7 / 12 HIS A 234
HIS A 265
GLU A 266
HIS A 269
GLU A 295
HIS A 408
TYR A 420
 None
ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
ZN  A 502 ( 3.3A)
ZN  A 502 ( 2.2A)
None
PO4  A 503 (-4.2A)
 0.60A 1j36B-3hq2A:
22.9		 1j36B-3hq2A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_A_X8ZA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		7 / 11 HIS A 234
HIS A 265
GLU A 266
HIS A 269
GLU A 295
HIS A 408
TYR A 420
 None
ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
ZN  A 502 ( 3.3A)
ZN  A 502 ( 2.2A)
None
PO4  A 503 (-4.2A)
 0.62A 1j37A-3hq2A:
22.9		 1j37A-3hq2A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J37_B_X8ZB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		7 / 11 HIS A 234
HIS A 265
GLU A 266
HIS A 269
GLU A 295
HIS A 408
TYR A 420
 None
ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
ZN  A 502 ( 3.3A)
ZN  A 502 ( 2.2A)
None
PO4  A 503 (-4.2A)
 0.61A 1j37B-3hq2A:
22.9		 1j37B-3hq2A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 8 ILE A 108
VAL A  24
MET A  27
SER A  31
 None
 0.92A 1kb9A-3hq2A:
undetectable
1kb9C-3hq2A:
1.0
1kb9D-3hq2A:
undetectable
1kb9E-3hq2A:
undetectable		 1kb9A-3hq2A:
22.41
1kb9C-3hq2A:
20.64
1kb9D-3hq2A:
17.93
1kb9E-3hq2A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		7 / 12 HIS A 234
HIS A 265
GLU A 266
HIS A 269
GLU A 295
HIS A 408
TYR A 420
 None
ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
ZN  A 502 ( 3.3A)
ZN  A 502 ( 2.2A)
None
PO4  A 503 (-4.2A)
 0.58A 1o86A-3hq2A:
23.7		 1o86A-3hq2A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_B_IU5B1002_1
(BILE ACID RECEPTOR)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 12 LEU A 358
SER A 342
ILE A 181
TYR A 424
TYR A 495
 None
 1.11A 1ot7B-3hq2A:
undetectable		 1ot7B-3hq2A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 12 ALA A 180
ILE A 181
ILE A 488
ALA A 428
LEU A 299
 None
 0.98A 1uduB-3hq2A:
undetectable		 1uduB-3hq2A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 8 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.39A 1utdB-3hq2A:
undetectable
1utdC-3hq2A:
undetectable		 1utdB-3hq2A:
8.96
1utdC-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.41A 1utdC-3hq2A:
undetectable
1utdD-3hq2A:
undetectable		 1utdC-3hq2A:
8.96
1utdD-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.40A 1utdD-3hq2A:
undetectable
1utdE-3hq2A:
undetectable		 1utdD-3hq2A:
8.96
1utdE-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 8 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.40A 1utdF-3hq2A:
undetectable
1utdG-3hq2A:
undetectable		 1utdF-3hq2A:
8.96
1utdG-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.38A 1utdG-3hq2A:
undetectable
1utdH-3hq2A:
undetectable		 1utdG-3hq2A:
8.96
1utdH-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 8 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.37A 1utdJ-3hq2A:
undetectable
1utdK-3hq2A:
undetectable		 1utdJ-3hq2A:
8.96
1utdK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.33A 1utdN-3hq2A:
undetectable
1utdO-3hq2A:
undetectable		 1utdN-3hq2A:
8.96
1utdO-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		7 / 12 HIS A 234
HIS A 265
GLU A 266
HIS A 269
GLU A 295
HIS A 408
TYR A 420
 None
ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
ZN  A 502 ( 3.3A)
ZN  A 502 ( 2.2A)
None
PO4  A 503 (-4.2A)
 0.60A 2c6nA-3hq2A:
22.6		 2c6nA-3hq2A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		7 / 12 HIS A 234
HIS A 265
GLU A 266
HIS A 269
GLU A 295
HIS A 408
TYR A 420
 None
ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
ZN  A 502 ( 3.3A)
ZN  A 502 ( 2.2A)
None
PO4  A 503 (-4.2A)
 0.63A 2c6nB-3hq2A:
22.6		 2c6nB-3hq2A:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8Z_A_X8ZA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		7 / 11 HIS A 234
HIS A 265
GLU A 266
HIS A 269
GLU A 295
HIS A 408
TYR A 420
 None
ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
ZN  A 502 ( 3.3A)
ZN  A 502 ( 2.2A)
None
PO4  A 503 (-4.2A)
 0.55A 2x8zA-3hq2A:
23.3		 2x8zA-3hq2A:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X8Z_A_X8ZA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 11 HIS A 408
GLU A 295
HIS A 265
GLU A 266
HIS A 234
 None
ZN  A 502 ( 2.2A)
ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
None
 1.32A 2x8zA-3hq2A:
23.3		 2x8zA-3hq2A:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		7 / 12 HIS A 234
HIS A 265
GLU A 266
HIS A 269
GLU A 295
HIS A 408
TYR A 420
 None
ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
ZN  A 502 ( 3.3A)
ZN  A 502 ( 2.2A)
None
PO4  A 503 (-4.2A)
 0.54A 2x91A-3hq2A:
23.3		 2x91A-3hq2A:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_1
(ANGIOTENSIN
CONVERTING ENZYME)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 12 HIS A 408
GLU A 295
HIS A 265
GLU A 266
HIS A 234
 None
ZN  A 502 ( 2.2A)
ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
None
 1.32A 2x91A-3hq2A:
23.3		 2x91A-3hq2A:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 7 GLU A 295
HIS A 265
HIS A 269
GLU A 266
 ZN  A 502 ( 2.2A)
ZN  A 502 ( 3.4A)
ZN  A 502 ( 3.3A)
PO4  A 503 (-3.0A)
 0.95A 3a6jB-3hq2A:
undetectable		 3a6jB-3hq2A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 6 ILE A 271
THR A 263
PHE A 224
TYR A 222
 None
 1.30A 3elzB-3hq2A:
undetectable		 3elzB-3hq2A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_C_ROFC903_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		3 / 3 SER A 298
GLN A 297
PHE A 300
 ZN  A 502 ( 3.7A)
None
None
 0.76A 3g4lC-3hq2A:
undetectable		 3g4lC-3hq2A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 12 LEU A 133
SER A 130
ILE A 403
LEU A 380
ASP A 379
 None
 1.03A 3ko0K-3hq2A:
undetectable
3ko0L-3hq2A:
undetectable
3ko0S-3hq2A:
undetectable
3ko0T-3hq2A:
undetectable		 3ko0K-3hq2A:
12.15
3ko0L-3hq2A:
12.15
3ko0S-3hq2A:
12.15
3ko0T-3hq2A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 12 LEU A 133
SER A 130
ILE A 403
LEU A 380
ASP A 379
 None
 1.13A 3ko0M-3hq2A:
undetectable
3ko0N-3hq2A:
undetectable
3ko0O-3hq2A:
undetectable
3ko0P-3hq2A:
undetectable		 3ko0M-3hq2A:
12.15
3ko0N-3hq2A:
12.15
3ko0O-3hq2A:
12.15
3ko0P-3hq2A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 12 LEU A 380
ASP A 379
LEU A 133
SER A 130
ILE A 403
 None
 1.08A 3ko0M-3hq2A:
undetectable
3ko0N-3hq2A:
undetectable
3ko0O-3hq2A:
undetectable
3ko0P-3hq2A:
undetectable		 3ko0M-3hq2A:
12.15
3ko0N-3hq2A:
12.15
3ko0O-3hq2A:
12.15
3ko0P-3hq2A:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TPX_E_ACTE204_0
(E3 UBIQUITIN-PROTEIN
LIGASE MDM2)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		3 / 3 LYS A 469
PRO A 470
LEU A 471
 None
 0.78A 3tpxE-3hq2A:
undetectable		 3tpxE-3hq2A:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C2P_A_X8ZA709_1
(ANGIOTENSIN-CONVERTI
NG ENZYME)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		7 / 11 HIS A 234
HIS A 265
GLU A 266
HIS A 269
GLU A 295
HIS A 408
TYR A 420
 None
ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
ZN  A 502 ( 3.3A)
ZN  A 502 ( 2.2A)
None
PO4  A 503 (-4.2A)
 0.74A 4c2pA-3hq2A:
23.1		 4c2pA-3hq2A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DPR_A_X8ZA702_1
(LEUKOTRIENE A-4
HYDROLASE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 HIS A 265
GLU A 266
GLU A 295
TYR A 416
TYR A 420
 ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
ZN  A 502 ( 2.2A)
None
PO4  A 503 (-4.2A)
 0.94A 4dprA-3hq2A:
6.9		 4dprA-3hq2A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 5 GLY A 411
GLY A 412
ASN A 140
GLU A 114
 CL  A 505 ( 4.0A)
None
None
ZN  A 504 ( 2.2A)
 1.30A 4fglC-3hq2A:
undetectable		 4fglC-3hq2A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 8 SER A 213
LEU A 212
PHE A 204
TYR A 251
 None
 0.92A 4j7uD-3hq2A:
undetectable		 4j7uD-3hq2A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7I_A_STIA1001_2
(MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 5 LEU A 471
VAL A 169
VAL A 484
ARG A 363
 None
 1.11A 4r7iA-3hq2A:
undetectable		 4r7iA-3hq2A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 12 GLU A 266
HIS A 265
GLU A 295
TYR A 416
TYR A 420
 PO4  A 503 (-3.0A)
ZN  A 502 ( 3.4A)
ZN  A 502 ( 2.2A)
None
PO4  A 503 (-4.2A)
 1.38A 4r7lA-3hq2A:
5.8		 4r7lA-3hq2A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 12 HIS A 265
GLU A 266
GLU A 295
TYR A 416
TYR A 420
 ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
ZN  A 502 ( 2.2A)
None
PO4  A 503 (-4.2A)
 0.96A 4r7lA-3hq2A:
5.8		 4r7lA-3hq2A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R7L_A_SHHA709_1
(LEUKOTRIENE A-4
HYDROLASE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 12 HIS A 265
GLU A 266
HIS A 269
GLU A 295
TYR A 420
 ZN  A 502 ( 3.4A)
PO4  A 503 (-3.0A)
ZN  A 502 ( 3.3A)
ZN  A 502 ( 2.2A)
PO4  A 503 (-4.2A)
 0.72A 4r7lA-3hq2A:
5.8		 4r7lA-3hq2A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 5 TYR A 426
TYR A 272
GLU A 162
ASP A 159
 None
 1.17A 4x61A-3hq2A:
0.0		 4x61A-3hq2A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5eeuC-3hq2A:
undetectable
5eeuD-3hq2A:
undetectable		 5eeuC-3hq2A:
8.96
5eeuD-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.37A 5eeuG-3hq2A:
undetectable
5eeuH-3hq2A:
undetectable		 5eeuG-3hq2A:
8.96
5eeuH-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5eeuJ-3hq2A:
undetectable
5eeuK-3hq2A:
undetectable		 5eeuJ-3hq2A:
8.96
5eeuK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.42A 5eeuA-3hq2A:
undetectable
5eeuK-3hq2A:
undetectable		 5eeuA-3hq2A:
8.96
5eeuK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.34A 5eeuP-3hq2A:
undetectable
5eeuQ-3hq2A:
undetectable		 5eeuP-3hq2A:
8.96
5eeuQ-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.35A 5eeuS-3hq2A:
undetectable
5eeuT-3hq2A:
undetectable		 5eeuS-3hq2A:
8.96
5eeuT-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.35A 5eeuT-3hq2A:
undetectable
5eeuU-3hq2A:
undetectable		 5eeuT-3hq2A:
8.96
5eeuU-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5eevB-3hq2A:
undetectable
5eevC-3hq2A:
undetectable		 5eevB-3hq2A:
8.96
5eevC-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5eevC-3hq2A:
undetectable
5eevD-3hq2A:
undetectable		 5eevC-3hq2A:
8.96
5eevD-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.37A 5eevG-3hq2A:
undetectable
5eevH-3hq2A:
undetectable		 5eevG-3hq2A:
8.96
5eevH-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5eevH-3hq2A:
undetectable
5eevI-3hq2A:
undetectable		 5eevH-3hq2A:
8.96
5eevI-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5eevJ-3hq2A:
undetectable
5eevK-3hq2A:
undetectable		 5eevJ-3hq2A:
8.96
5eevK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.42A 5eevA-3hq2A:
undetectable
5eevK-3hq2A:
undetectable		 5eevA-3hq2A:
8.96
5eevK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.34A 5eevP-3hq2A:
undetectable
5eevQ-3hq2A:
undetectable		 5eevP-3hq2A:
8.96
5eevQ-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.35A 5eevS-3hq2A:
undetectable
5eevT-3hq2A:
undetectable		 5eevS-3hq2A:
8.96
5eevT-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5eewB-3hq2A:
undetectable
5eewC-3hq2A:
undetectable		 5eewB-3hq2A:
8.96
5eewC-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5eewC-3hq2A:
undetectable
5eewD-3hq2A:
undetectable		 5eewC-3hq2A:
8.96
5eewD-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.37A 5eewG-3hq2A:
undetectable
5eewH-3hq2A:
undetectable		 5eewG-3hq2A:
8.96
5eewH-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5eewH-3hq2A:
undetectable
5eewI-3hq2A:
undetectable		 5eewH-3hq2A:
8.96
5eewI-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.42A 5eewA-3hq2A:
undetectable
5eewK-3hq2A:
undetectable		 5eewA-3hq2A:
8.96
5eewK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.34A 5eewP-3hq2A:
undetectable
5eewQ-3hq2A:
undetectable		 5eewP-3hq2A:
8.96
5eewQ-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.35A 5eewS-3hq2A:
undetectable
5eewT-3hq2A:
undetectable		 5eewS-3hq2A:
8.96
5eewT-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5eexB-3hq2A:
undetectable
5eexC-3hq2A:
undetectable		 5eexB-3hq2A:
8.96
5eexC-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5eexC-3hq2A:
undetectable
5eexD-3hq2A:
undetectable		 5eexC-3hq2A:
8.96
5eexD-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.41A 5eexE-3hq2A:
undetectable
5eexF-3hq2A:
undetectable		 5eexE-3hq2A:
8.96
5eexF-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.37A 5eexG-3hq2A:
undetectable
5eexH-3hq2A:
undetectable		 5eexG-3hq2A:
8.96
5eexH-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5eexH-3hq2A:
undetectable
5eexI-3hq2A:
undetectable		 5eexH-3hq2A:
8.96
5eexI-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5eexJ-3hq2A:
undetectable
5eexK-3hq2A:
undetectable		 5eexJ-3hq2A:
8.96
5eexK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.42A 5eexA-3hq2A:
undetectable
5eexK-3hq2A:
undetectable		 5eexA-3hq2A:
8.96
5eexK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.34A 5eexP-3hq2A:
undetectable
5eexQ-3hq2A:
undetectable		 5eexP-3hq2A:
8.96
5eexQ-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.35A 5eexS-3hq2A:
undetectable
5eexT-3hq2A:
undetectable		 5eexS-3hq2A:
8.96
5eexT-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.38A 5eeyB-3hq2A:
undetectable
5eeyC-3hq2A:
undetectable		 5eeyB-3hq2A:
8.96
5eeyC-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5eeyC-3hq2A:
undetectable
5eeyD-3hq2A:
undetectable		 5eeyC-3hq2A:
8.96
5eeyD-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.41A 5eeyE-3hq2A:
undetectable
5eeyF-3hq2A:
undetectable		 5eeyE-3hq2A:
8.96
5eeyF-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.37A 5eeyG-3hq2A:
undetectable
5eeyH-3hq2A:
undetectable		 5eeyG-3hq2A:
8.96
5eeyH-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5eeyH-3hq2A:
undetectable
5eeyI-3hq2A:
undetectable		 5eeyH-3hq2A:
8.96
5eeyI-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5eeyJ-3hq2A:
undetectable
5eeyK-3hq2A:
undetectable		 5eeyJ-3hq2A:
8.96
5eeyK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.41A 5eeyA-3hq2A:
undetectable
5eeyK-3hq2A:
undetectable		 5eeyA-3hq2A:
8.96
5eeyK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.34A 5eeyP-3hq2A:
undetectable
5eeyQ-3hq2A:
undetectable		 5eeyP-3hq2A:
8.96
5eeyQ-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.35A 5eeyS-3hq2A:
undetectable
5eeyT-3hq2A:
undetectable		 5eeyS-3hq2A:
8.96
5eeyT-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.38A 5eezB-3hq2A:
undetectable
5eezC-3hq2A:
undetectable		 5eezB-3hq2A:
8.96
5eezC-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5eezC-3hq2A:
undetectable
5eezD-3hq2A:
undetectable		 5eezC-3hq2A:
8.96
5eezD-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.41A 5eezE-3hq2A:
undetectable
5eezF-3hq2A:
undetectable		 5eezE-3hq2A:
8.96
5eezF-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.37A 5eezG-3hq2A:
undetectable
5eezH-3hq2A:
undetectable		 5eezG-3hq2A:
8.96
5eezH-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5eezH-3hq2A:
undetectable
5eezI-3hq2A:
undetectable		 5eezH-3hq2A:
8.96
5eezI-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5eezJ-3hq2A:
undetectable
5eezK-3hq2A:
undetectable		 5eezJ-3hq2A:
8.96
5eezK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.41A 5eezA-3hq2A:
undetectable
5eezK-3hq2A:
undetectable		 5eezA-3hq2A:
8.96
5eezK-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.34A 5eezP-3hq2A:
undetectable
5eezQ-3hq2A:
undetectable		 5eezP-3hq2A:
8.96
5eezQ-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.36A 5eezS-3hq2A:
undetectable
5eezT-3hq2A:
undetectable		 5eezS-3hq2A:
8.96
5eezT-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.38A 5ef0B-3hq2A:
undetectable
5ef0C-3hq2A:
undetectable		 5ef0B-3hq2A:
8.96
5ef0C-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5ef0C-3hq2A:
undetectable
5ef0D-3hq2A:
undetectable		 5ef0C-3hq2A:
8.96
5ef0D-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.41A 5ef0E-3hq2A:
undetectable
5ef0F-3hq2A:
undetectable		 5ef0E-3hq2A:
8.96
5ef0F-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.37A 5ef0G-3hq2A:
undetectable
5ef0H-3hq2A:
undetectable		 5ef0G-3hq2A:
8.96
5ef0H-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5ef0H-3hq2A:
undetectable
5ef0I-3hq2A:
undetectable		 5ef0H-3hq2A:
8.96
5ef0I-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5ef0J-3hq2A:
undetectable
5ef0K-3hq2A:
undetectable		 5ef0J-3hq2A:
8.96
5ef0K-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.41A 5ef0A-3hq2A:
undetectable
5ef0K-3hq2A:
undetectable		 5ef0A-3hq2A:
8.96
5ef0K-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.34A 5ef0P-3hq2A:
undetectable
5ef0Q-3hq2A:
undetectable		 5ef0P-3hq2A:
8.96
5ef0Q-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.36A 5ef0S-3hq2A:
undetectable
5ef0T-3hq2A:
undetectable		 5ef0S-3hq2A:
8.96
5ef0T-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.38A 5ef1B-3hq2A:
undetectable
5ef1C-3hq2A:
undetectable		 5ef1B-3hq2A:
8.96
5ef1C-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5ef1C-3hq2A:
undetectable
5ef1D-3hq2A:
undetectable		 5ef1C-3hq2A:
8.96
5ef1D-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5ef1E-3hq2A:
undetectable
5ef1F-3hq2A:
undetectable		 5ef1E-3hq2A:
8.96
5ef1F-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.37A 5ef1G-3hq2A:
undetectable
5ef1H-3hq2A:
undetectable		 5ef1G-3hq2A:
8.96
5ef1H-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5ef1H-3hq2A:
undetectable
5ef1I-3hq2A:
undetectable		 5ef1H-3hq2A:
8.96
5ef1I-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5ef1J-3hq2A:
undetectable
5ef1K-3hq2A:
undetectable		 5ef1J-3hq2A:
8.96
5ef1K-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.41A 5ef1A-3hq2A:
undetectable
5ef1K-3hq2A:
undetectable		 5ef1A-3hq2A:
8.96
5ef1K-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.34A 5ef1P-3hq2A:
undetectable
5ef1Q-3hq2A:
undetectable		 5ef1P-3hq2A:
8.96
5ef1Q-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.35A 5ef1S-3hq2A:
undetectable
5ef1T-3hq2A:
undetectable		 5ef1S-3hq2A:
8.96
5ef1T-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.32A 5ef1U-3hq2A:
undetectable
5ef1V-3hq2A:
undetectable		 5ef1U-3hq2A:
8.96
5ef1V-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.38A 5ef2B-3hq2A:
undetectable
5ef2C-3hq2A:
undetectable		 5ef2B-3hq2A:
8.96
5ef2C-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5ef2C-3hq2A:
undetectable
5ef2D-3hq2A:
undetectable		 5ef2C-3hq2A:
8.96
5ef2D-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5ef2E-3hq2A:
undetectable
5ef2F-3hq2A:
undetectable		 5ef2E-3hq2A:
8.96
5ef2F-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.37A 5ef2G-3hq2A:
undetectable
5ef2H-3hq2A:
undetectable		 5ef2G-3hq2A:
8.96
5ef2H-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5ef2H-3hq2A:
undetectable
5ef2I-3hq2A:
undetectable		 5ef2H-3hq2A:
8.96
5ef2I-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5ef2J-3hq2A:
undetectable
5ef2K-3hq2A:
undetectable		 5ef2J-3hq2A:
8.96
5ef2K-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.41A 5ef2A-3hq2A:
undetectable
5ef2K-3hq2A:
undetectable		 5ef2A-3hq2A:
8.96
5ef2K-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.33A 5ef2P-3hq2A:
undetectable
5ef2Q-3hq2A:
undetectable		 5ef2P-3hq2A:
8.96
5ef2Q-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.35A 5ef2S-3hq2A:
undetectable
5ef2T-3hq2A:
undetectable		 5ef2S-3hq2A:
8.96
5ef2T-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.32A 5ef2U-3hq2A:
undetectable
5ef2V-3hq2A:
undetectable		 5ef2U-3hq2A:
8.96
5ef2V-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.38A 5ef3B-3hq2A:
undetectable
5ef3C-3hq2A:
undetectable		 5ef3B-3hq2A:
8.96
5ef3C-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5ef3C-3hq2A:
undetectable
5ef3D-3hq2A:
undetectable		 5ef3C-3hq2A:
8.96
5ef3D-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.40A 5ef3E-3hq2A:
undetectable
5ef3F-3hq2A:
undetectable		 5ef3E-3hq2A:
8.96
5ef3F-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.37A 5ef3G-3hq2A:
undetectable
5ef3H-3hq2A:
undetectable		 5ef3G-3hq2A:
8.96
5ef3H-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.38A 5ef3H-3hq2A:
undetectable
5ef3I-3hq2A:
undetectable		 5ef3H-3hq2A:
8.96
5ef3I-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 THR A 189
SER A 342
GLY A 393
THR A 355
ILE A 394
 None
 1.39A 5ef3J-3hq2A:
undetectable
5ef3K-3hq2A:
undetectable		 5ef3J-3hq2A:
8.96
5ef3K-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.41A 5ef3A-3hq2A:
undetectable
5ef3K-3hq2A:
undetectable		 5ef3A-3hq2A:
8.96
5ef3K-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.33A 5ef3P-3hq2A:
undetectable
5ef3Q-3hq2A:
undetectable		 5ef3P-3hq2A:
8.96
5ef3Q-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.36A 5ef3S-3hq2A:
undetectable
5ef3T-3hq2A:
undetectable		 5ef3S-3hq2A:
8.96
5ef3T-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 GLY A 393
THR A 355
ILE A 394
THR A 189
SER A 342
 None
 1.32A 5ef3U-3hq2A:
undetectable
5ef3V-3hq2A:
undetectable		 5ef3U-3hq2A:
8.96
5ef3V-3hq2A:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EML_A_SAMA701_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 6 TYR A 426
TYR A 272
GLU A 162
ASP A 159
 None
 1.17A 5emlA-3hq2A:
undetectable		 5emlA-3hq2A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 5 GLU A 273
THR A 238
GLU A 266
THR A 263
 None
None
PO4  A 503 (-3.0A)
None
 1.15A 5hm8A-3hq2A:
undetectable		 5hm8A-3hq2A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 5 GLU A 273
THR A 238
GLU A 266
THR A 263
 None
None
PO4  A 503 (-3.0A)
None
 1.15A 5hm8B-3hq2A:
undetectable		 5hm8B-3hq2A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 5 GLU A 273
THR A 238
GLU A 266
THR A 263
 None
None
PO4  A 503 (-3.0A)
None
 1.16A 5hm8C-3hq2A:
undetectable		 5hm8C-3hq2A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 5 GLU A 273
THR A 238
GLU A 266
THR A 263
 None
None
PO4  A 503 (-3.0A)
None
 1.15A 5hm8D-3hq2A:
undetectable		 5hm8D-3hq2A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 5 GLU A 273
THR A 238
GLU A 266
THR A 263
 None
None
PO4  A 503 (-3.0A)
None
 1.15A 5hm8E-3hq2A:
undetectable		 5hm8E-3hq2A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 5 GLU A 273
THR A 238
GLU A 266
THR A 263
 None
None
PO4  A 503 (-3.0A)
None
 1.15A 5hm8F-3hq2A:
undetectable		 5hm8F-3hq2A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 5 GLU A 273
THR A 238
GLU A 266
THR A 263
 None
None
PO4  A 503 (-3.0A)
None
 1.21A 5hm8G-3hq2A:
undetectable		 5hm8G-3hq2A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 5 GLU A 273
THR A 238
GLU A 266
THR A 263
 None
None
PO4  A 503 (-3.0A)
None
 1.15A 5hm8H-3hq2A:
undetectable		 5hm8H-3hq2A:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 9 LEU A 487
LEU A 491
ILE A 361
LEU A 173
PRO A 183
 None
 1.11A 5og9A-3hq2A:
0.8		 5og9A-3hq2A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TQR_B_SAMB8009_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EZH2, POLYCOMB
PROTEIN SUZ12)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 10 LEU A 220
CYH A 267
GLY A 268
VAL A 245
TYR A 272
 None
 1.45A 5tqrB-3hq2A:
undetectable		 5tqrB-3hq2A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_A_ZITA501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		4 / 7 GLU A 367
TYR A 154
PHE A 371
GLY A 411
 None
None
None
CL  A 505 ( 4.0A)
 0.85A 5uxdA-3hq2A:
undetectable		 5uxdA-3hq2A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 12 LEU A  87
VAL A 461
ILE A 473
ASP A 472
ASP A 476
 None
 1.34A 6bxnA-3hq2A:
undetectable		 6bxnA-3hq2A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBP_B_ADNB404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3hq2 BACILLUS SUBTILIS
M32 CARBOXYPEPTIDASE
(Bacillus
subtilis) 		5 / 12 ILE A 474
ILE A 293
HIS A 464
SER A 296
ASP A 476
 None
 1.36A 6fbpA-3hq2A:
undetectable
6fbpB-3hq2A:
undetectable		 6fbpA-3hq2A:
9.37
6fbpB-3hq2A:
9.37