SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3002_1
(SERUM ALBUMIN)		 3hq9 CYTOCHROME C551
PEROXIDASE
(Geobacter
sulfurreducens) 		4 / 8 GLN A 207
LEU A 228
LEU A 196
SER A 190
 None
 1.04A 1hk2A-3hq9A:
undetectable		 1hk2A-3hq9A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3hq9 CYTOCHROME C551
PEROXIDASE
(Geobacter
sulfurreducens) 		4 / 7 VAL A 294
PHE A 214
LEU A 215
ALA A  29
 HEM  A 401 ( 3.9A)
None
None
None
 0.76A 1j8uA-3hq9A:
undetectable		 1j8uA-3hq9A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 3hq9 CYTOCHROME C551
PEROXIDASE
(Geobacter
sulfurreducens) 		3 / 3 PHE A 158
LEU A  55
MET A 333
 None
 0.85A 1mx1D-3hq9A:
undetectable		 1mx1D-3hq9A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 3hq9 CYTOCHROME C551
PEROXIDASE
(Geobacter
sulfurreducens) 		3 / 3 ASP A 193
LEU A 196
HIS A 223
 None
None
HEM  A 401 (-3.2A)
 0.74A 1qknA-3hq9A:
undetectable		 1qknA-3hq9A:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3hq9 CYTOCHROME C551
PEROXIDASE
(Geobacter
sulfurreducens) 		3 / 3 ASN A 101
HIS A 283
VAL A 238
 CA  A 402 (-2.9A)
HEM  A 401 (-3.7A)
HEM  A 401 (-3.8A)
 0.86A 3elzB-3hq9A:
undetectable		 3elzB-3hq9A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 3hq9 CYTOCHROME C551
PEROXIDASE
(Geobacter
sulfurreducens) 		5 / 12 LEU A 228
ASN A 227
GLY A 229
THR A 187
VAL A  36
 None
 1.27A 3gn8A-3hq9A:
undetectable		 3gn8A-3hq9A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 3hq9 CYTOCHROME C551
PEROXIDASE
(Geobacter
sulfurreducens) 		5 / 12 LEU A 228
ASN A 227
GLY A 230
THR A 187
VAL A  36
 None
 1.15A 3gn8A-3hq9A:
undetectable		 3gn8A-3hq9A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_D_NCTD501_1
(CYTOCHROME P450 2A13)		 3hq9 CYTOCHROME C551
PEROXIDASE
(Geobacter
sulfurreducens) 		4 / 6 PHE A 158
ASN A 173
ALA A 175
LEU A  65
 None
None
None
OXL  A 348 ( 3.9A)
 1.04A 4ejgD-3hq9A:
undetectable		 4ejgD-3hq9A:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3hq9 CYTOCHROME C551
PEROXIDASE
(Geobacter
sulfurreducens) 		4 / 6 PHE A 162
PRO A 163
GLY A 164
LYS A 166
 None
 0.98A 5x24A-3hq9A:
undetectable		 5x24A-3hq9A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 3hq9 CYTOCHROME C551
PEROXIDASE
(Geobacter
sulfurreducens) 		4 / 6 LEU A 203
GLN A 207
LEU A 318
LEU A 321
 None
 1.01A 5yvnA-3hq9A:
undetectable		 5yvnA-3hq9A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_K_PACK1_0
(SERINE PROTEASE NS3
PEPTIDE
PAC-DLY-DLY-DAR)		 3hq9 CYTOCHROME C551
PEROXIDASE
(Geobacter
sulfurreducens) 		3 / 3 ALA A 315
VAL A 287
TYR A 281
 None
 0.54A 5zmqH-3hq9A:
undetectable		 5zmqH-3hq9A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 3hq9 CYTOCHROME C551
PEROXIDASE
(Geobacter
sulfurreducens) 		4 / 8 GLY A  92
ASP A  85
HIS A  77
PRO A 103
 HEM  A 400 (-3.6A)
None
HEM  A 400 (-3.2A)
HEM  A 400 (-4.3A)
 1.04A 6ag0C-3hq9A:
undetectable		 6ag0C-3hq9A:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 3hq9 CYTOCHROME C551
PEROXIDASE
(Geobacter
sulfurreducens) 		3 / 3 PHE A 115
ARG A 268
GLN A 114
 BU3  A 350 ( 4.2A)
HEM  A 400 (-4.3A)
BU3  A 350 (-4.1A)
 1.00A 6g1pB-3hq9A:
undetectable		 6g1pB-3hq9A:
24.47