SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hqi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 3hqi SPECKLE-TYPE POZ
PROTEIN
(Homo
sapiens) 		4 / 7 VAL A 163
GLN A 165
LEU A  65
ASP A  63
 None
 1.25A 4hxyB-3hqiA:
undetectable		 4hxyB-3hqiA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 3hqi SPECKLE-TYPE POZ
PROTEIN
(Homo
sapiens) 		5 / 12 VAL A 206
ALA A 207
PHE A 225
PHE A 251
VAL A 250
 None
 1.26A 4mm6A-3hqiA:
undetectable		 4mm6A-3hqiA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 3hqi SPECKLE-TYPE POZ
PROTEIN
(Homo
sapiens) 		3 / 3 MET A 255
MET A 288
TYR A 280
 None
 1.19A 4p6xI-3hqiA:
undetectable		 4p6xI-3hqiA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 3hqi SPECKLE-TYPE POZ
PROTEIN
(Homo
sapiens) 		3 / 3 ASP A 130
TYR A  87
TRP A 131
 None
 1.32A 4p7nA-3hqiA:
undetectable		 4p7nA-3hqiA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 3hqi SPECKLE-TYPE POZ
PROTEIN
(Homo
sapiens) 		4 / 5 LEU A 308
ALA A 275
LEU A 311
VAL A 246
 None
 1.20A 5cr1A-3hqiA:
undetectable		 5cr1A-3hqiA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_B_ACTB207_0
(DUF1778
DOMAIN-CONTAINING
PROTEIN
N-ACETYLTRANSFERASE)		 3hqi SPECKLE-TYPE POZ
PROTEIN
(Homo
sapiens) 		4 / 6 LEU A 282
GLY A 261
ARG A 221
ARG A 284
 None
 1.16A 6gtqB-3hqiA:
undetectable
6gtqD-3hqiA:
undetectable		 6gtqB-3hqiA:
18.59
6gtqD-3hqiA:
8.75