SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hr6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 3hr6 PUTATIVE
SURFACE-ANCHORED
FIMBRIAL SUBUNIT
(Corynebacterium
diphtheriae) 		4 / 7 VAL A 185
LEU A  91
VAL A 151
LEU A  99
 None
 0.81A 1cqpA-3hr6A:
undetectable
1cqpB-3hr6A:
undetectable		 1cqpA-3hr6A:
20.05
1cqpB-3hr6A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 3hr6 PUTATIVE
SURFACE-ANCHORED
FIMBRIAL SUBUNIT
(Corynebacterium
diphtheriae) 		3 / 3 LEU A 243
PRO A 244
LEU A 247
 None
 0.54A 1hrkA-3hr6A:
undetectable		 1hrkA-3hr6A:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3hr6 PUTATIVE
SURFACE-ANCHORED
FIMBRIAL SUBUNIT
(Corynebacterium
diphtheriae) 		4 / 8 ARG A 351
HIS A 418
SER A 354
VAL A 352
 None
IOD  A 487 (-4.7A)
None
None
 1.11A 1u1jA-3hr6A:
undetectable		 1u1jA-3hr6A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_B_PFNB1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3hr6 PUTATIVE
SURFACE-ANCHORED
FIMBRIAL SUBUNIT
(Corynebacterium
diphtheriae) 		4 / 4 TYR A 188
LEU A  81
LEU A  62
HIS A  60
 None
 1.49A 2x7hB-3hr6A:
undetectable		 2x7hB-3hr6A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hr6 PUTATIVE
SURFACE-ANCHORED
FIMBRIAL SUBUNIT
(Corynebacterium
diphtheriae) 		4 / 7 ILE A 417
LEU A 464
PHE A 442
THR A 421
 None
None
None
IOD  A 487 (-3.9A)
 1.04A 3ag4N-3hr6A:
undetectable
3ag4W-3hr6A:
undetectable		 3ag4N-3hr6A:
21.15
3ag4W-3hr6A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_2
(CYTOCHROME P450 3A4)		 3hr6 PUTATIVE
SURFACE-ANCHORED
FIMBRIAL SUBUNIT
(Corynebacterium
diphtheriae) 		5 / 9 ARG A 163
THR A 131
ARG A 345
LEU A 344
GLY A  86
 None
 1.49A 3nxuB-3hr6A:
undetectable		 3nxuB-3hr6A:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 3hr6 PUTATIVE
SURFACE-ANCHORED
FIMBRIAL SUBUNIT
(Corynebacterium
diphtheriae) 		4 / 5 LEU A 344
ARG A 163
LEU A 326
PRO A 330
 None
 1.34A 3onnA-3hr6A:
undetectable		 3onnA-3hr6A:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW7_A_VPXA2001_2
(PROTEINASE-ACTIVATED
RECEPTOR 1, LYSOZYME)		 3hr6 PUTATIVE
SURFACE-ANCHORED
FIMBRIAL SUBUNIT
(Corynebacterium
diphtheriae) 		4 / 4 PRO A 348
LEU A 194
HIS A 191
LEU A  62
 None
 1.47A 3vw7A-3hr6A:
undetectable		 3vw7A-3hr6A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3hr6 PUTATIVE
SURFACE-ANCHORED
FIMBRIAL SUBUNIT
(Corynebacterium
diphtheriae) 		3 / 3 SER A  88
ASP A 335
ASP A 341
 None
 0.57A 4uckA-3hr6A:
undetectable		 4uckA-3hr6A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4USW_A_ACTA1470_0
(ADENYLATE CYCLASE
TYPE 10)		 3hr6 PUTATIVE
SURFACE-ANCHORED
FIMBRIAL SUBUNIT
(Corynebacterium
diphtheriae) 		4 / 6 LEU A 419
LEU A 473
VAL A 474
PHE A 356
 None
 1.03A 4uswA-3hr6A:
undetectable		 4uswA-3hr6A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hr6 PUTATIVE
SURFACE-ANCHORED
FIMBRIAL SUBUNIT
(Corynebacterium
diphtheriae) 		4 / 6 ILE A 417
LEU A 464
PHE A 442
THR A 421
 None
None
None
IOD  A 487 (-3.9A)
 1.01A 5b1aN-3hr6A:
undetectable
5b1aW-3hr6A:
undetectable		 5b1aN-3hr6A:
21.15
5b1aW-3hr6A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 3hr6 PUTATIVE
SURFACE-ANCHORED
FIMBRIAL SUBUNIT
(Corynebacterium
diphtheriae) 		4 / 8 GLY A 416
GLN A 358
SER A 212
PHE A 442
 None
 1.16A 6eqpA-3hr6A:
undetectable		 6eqpA-3hr6A:
13.68