SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hrd'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C9S_N_TRPN81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	5 / 10	GLY B  14 HIS A 323 ALA B  86 ILE B  15 GLY A 354	None None NIO  B5661 ( 3.7A) None NO3  A5658 (-3.7A)	1.05A	1c9sN-3hrdB: undetectable 1c9sO-3hrdB: undetectable	1c9sN-3hrdB: 13.64 1c9sO-3hrdB: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C9S_P_TRPP81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	5 / 11	GLY B  14 HIS A 323 ALA B  86 ILE B  15 GLY A 354	None None NIO  B5661 ( 3.7A) None NO3  A5658 (-3.7A)	1.04A	1c9sP-3hrdB: undetectable 1c9sQ-3hrdB: undetectable	1c9sP-3hrdB: 13.64 1c9sQ-3hrdB: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C9S_V_TRPV81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	5 / 10	GLY A 354 GLY B  14 HIS A 323 ALA B  86 ILE B  15	NO3  A5658 (-3.7A) None None NIO  B5661 ( 3.7A) None	1.05A	1c9sL-3hrdA: undetectable 1c9sV-3hrdA: undetectable	1c9sL-3hrdA: 10.39 1c9sV-3hrdA: 10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1D0V_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	4 / 8	THR D  60 GLY D  45 GLY C 109 GLY C  33	FES  D 908 (-4.2A) FES  D 908 ( 3.2A) FAD  C 900 ( 3.8A) FAD  C 900 (-3.3A)	0.66A	1d0vA-3hrdD: undetectable	1d0vA-3hrdD: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DZ9_A_CAMA503_0 (CYTOCHROME P450-CAM)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	4 / 8	TYR B 184 LEU A 398 THR A 394 VAL A 322	None	1.15A	1dz9A-3hrdB: undetectable	1dz9A-3hrdB: 19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EPB_A_9CRA165_2 (EPIDIDYMAL RETINOIC ACID-BINDING PROTEIN)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 7	PHE B 311 ALA B 189 VAL B 205 VAL B 202	None	0.87A	1epbA-3hrdB: undetectable	1epbA-3hrdB: 20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_Q_TRPQ81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	5 / 11	GLY B  14 HIS A 323 ALA B  86 ILE B  15 GLY A 354	None None NIO  B5661 ( 3.7A) None NO3  A5658 (-3.7A)	1.05A	1gtfQ-3hrdB: undetectable 1gtfR-3hrdB: undetectable	1gtfQ-3hrdB: 13.64 1gtfR-3hrdB: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTF_S_TRPS81_0 (TRP RNA-BINDING ATTENUATION PROTEIN (TRAP))	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	5 / 11	GLY B  14 HIS A 323 ALA B  86 ILE B  15 GLY A 354	None None NIO  B5661 ( 3.7A) None NO3  A5658 (-3.7A)	1.06A	1gtfS-3hrdB: undetectable 1gtfT-3hrdB: undetectable	1gtfS-3hrdB: 13.64 1gtfT-3hrdB: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_T_TRPT81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	5 / 11	GLY B  14 HIS A 323 ALA B  86 ILE B  15 GLY A 354	None None NIO  B5661 ( 3.7A) None NO3  A5658 (-3.7A)	1.08A	1gtnT-3hrdB: undetectable 1gtnU-3hrdB: undetectable	1gtnT-3hrdB: 13.64 1gtnU-3hrdB: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GX8_A_RTLA1163_0 (BETA-LACTOGLOBULIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 9	LEU A 243 GLU A 216 LYS A  85 ILE A  83 VAL A 316	MOS  B 920 ( 4.9A) None None NIO  B5661 ( 4.7A) NO3  A5658 (-4.6A)	1.32A	1gx8A-3hrdA: undetectable	1gx8A-3hrdA: 16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1H4O_A_BEZA1162_0 (PEROXIREDOXIN 5)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	5 / 10	THR B  90 GLY B 286 LEU A   8 THR B 213 GLY B 283	MCN  B 921 (-3.5A) MCN  B 921 (-3.2A) None None None	1.30A	1h4oA-3hrdB: undetectable 1h4oB-3hrdB: undetectable	1h4oA-3hrdB: 22.80 1h4oB-3hrdB: 22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ICT_C_T44C128_1 (TRANSTHYRETIN)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 11	ALA B 156 LEU B 145 GLU B 114 ALA B 109 SER B 124	None	1.21A	1ictA-3hrdB: undetectable 1ictC-3hrdB: undetectable	1ictA-3hrdB: 16.56 1ictC-3hrdB: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IE9_A_VDXA500_1 (VITAMIN D3 RECEPTOR)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	LEU A 254 LEU A 253 CYH A  89 VAL A 105 LEU A  56	None	1.24A	1ie9A-3hrdA: undetectable	1ie9A-3hrdA: 19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHA_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	4 / 8	THR D  60 GLY D  45 GLY C 109 GLY C  33	FES  D 908 (-4.2A) FES  D 908 ( 3.2A) FAD  C 900 ( 3.8A) FAD  C 900 (-3.3A)	0.65A	1jhaA-3hrdD: undetectable	1jhaA-3hrdD: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHO_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 9	THR D  60 GLY D  45 GLY C 109 LEU C 108 GLY C  33	FES  D 908 (-4.2A) FES  D 908 ( 3.2A) FAD  C 900 ( 3.8A) None FAD  C 900 (-3.3A)	0.90A	1jhoA-3hrdD: undetectable	1jhoA-3hrdD: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHR_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 9	THR D  60 GLY D  45 GLY C 109 LEU C 108 GLY C  33	FES  D 908 (-4.2A) FES  D 908 ( 3.2A) FAD  C 900 ( 3.8A) None FAD  C 900 (-3.3A)	0.93A	1jhrA-3hrdD: undetectable	1jhrA-3hrdD: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JHY_A_NIOA991_1 (NICOTINATE MONONUCLEOTIDE:5,6-D IMETHYLBENZIMIDAZOLE PHOSPHORIBOSYLTRANSF ERASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 9	THR D  60 GLY D  45 GLY C 109 LEU C 108 GLY C  33	FES  D 908 (-4.2A) FES  D 908 ( 3.2A) FAD  C 900 ( 3.8A) None FAD  C 900 (-3.3A)	0.90A	1jhyA-3hrdD: undetectable	1jhyA-3hrdD: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L4N_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 9	THR D  60 GLY D  45 GLY C 109 LEU C 108 GLY C  33	FES  D 908 (-4.2A) FES  D 908 ( 3.2A) FAD  C 900 ( 3.8A) None FAD  C 900 (-3.3A)	0.92A	1l4nA-3hrdD: undetectable	1l4nA-3hrdD: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5K_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 9	THR D  60 GLY D  45 GLY C 109 LEU C 108 GLY C  33	FES  D 908 (-4.2A) FES  D 908 ( 3.2A) FAD  C 900 ( 3.8A) None FAD  C 900 (-3.3A)	0.92A	1l5kA-3hrdD: undetectable	1l5kA-3hrdD: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5L_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 9	THR D  60 GLY D  45 GLY C 109 LEU C 108 GLY C  33	FES  D 908 (-4.2A) FES  D 908 ( 3.2A) FAD  C 900 ( 3.8A) None FAD  C 900 (-3.3A)	0.91A	1l5lA-3hrdD: undetectable	1l5lA-3hrdD: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1L5M_A_NIOA991_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 9	THR D  60 GLY D  45 GLY C 109 LEU C 108 GLY C  33	FES  D 908 (-4.2A) FES  D 908 ( 3.2A) FAD  C 900 ( 3.8A) None FAD  C 900 (-3.3A)	0.90A	1l5mA-3hrdD: undetectable	1l5mA-3hrdD: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJQ_D_SAMD200_0 (METHIONINE REPRESSOR)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	GLY A 326 ARG A 294 LEU A 383 ALA A 385 HIS A 386	None	1.04A	1mjqC-3hrdA: undetectable 1mjqD-3hrdA: undetectable	1mjqC-3hrdA: 12.71 1mjqD-3hrdA: 12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJQ_J_SAMJ200_0 (METHIONINE REPRESSOR)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	GLY A 326 ARG A 294 LEU A 383 ALA A 385 HIS A 386	None	1.04A	1mjqI-3hrdA: undetectable 1mjqJ-3hrdA: undetectable	1mjqI-3hrdA: 12.71 1mjqJ-3hrdA: 12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PXX_A_DIFA701_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 10	VAL A 247 LEU A 117 VAL A 104 GLY A  40 ALA A  39	None	1.07A	1pxxA-3hrdA: undetectable	1pxxA-3hrdA: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PXX_B_DIFB1701_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 9	VAL A 247 LEU A 117 VAL A 104 GLY A  40 ALA A  39	None	1.07A	1pxxB-3hrdA: undetectable	1pxxB-3hrdA: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PXX_C_DIFC2701_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	VAL A 247 LEU A 117 VAL A 104 GLY A  40 ALA A  39	None	1.07A	1pxxC-3hrdA: undetectable	1pxxC-3hrdA: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PXX_D_DIFD3701_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 10	VAL A 247 LEU A 117 VAL A 104 GLY A  40 ALA A  39	None	1.07A	1pxxD-3hrdA: undetectable	1pxxD-3hrdA: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UTD_S_TRPS81_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	5 / 11	GLY B  14 HIS A 323 ALA B  86 ILE B  15 GLY A 354	None None NIO  B5661 ( 3.7A) None NO3  A5658 (-3.7A)	1.05A	1utdS-3hrdB: undetectable 1utdT-3hrdB: undetectable	1utdS-3hrdB: 13.64 1utdT-3hrdB: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UTD_U_TRPU81_0 (TRANSCRIPTION ATTENUATION PROTEIN MTRB)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	5 / 10	GLY B  14 HIS A 323 ALA B  86 ILE B  15 GLY A 354	None None NIO  B5661 ( 3.7A) None NO3  A5658 (-3.7A)	1.08A	1utdU-3hrdB: undetectable 1utdV-3hrdB: undetectable	1utdU-3hrdB: 13.64 1utdV-3hrdB: 13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1VM1_A_TAZA504_1 (BETA-LACTAMASE SHV-1)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	3 / 3	ASP C 256 TYR C 259 GLU C 273	None	0.80A	1vm1A-3hrdC: undetectable	1vm1A-3hrdC: 21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YMX_B_CFXB1002_2 (BETA-LACTAMASE CTX-M-9)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 5	CYH A 324 TYR B 182 THR B  18 THR A 318	None None NIO  B5661 (-3.9A) None	1.38A	1ymxB-3hrdA: undetectable	1ymxB-3hrdA: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_A_ACTA1502_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	3hrd	NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	4 / 5	PRO D  58 GLY D  48 ASN D 134 GLY D 133	None FES  D 908 (-3.8A) None None	1.10A	1zlqA-3hrdD: undetectable	1zlqA-3hrdD: 15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_A_ACTA1502_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	3hrd	NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	4 / 5	PRO D  58 GLY D 107 ASN D 134 GLY D  48	None None None FES  D 908 (-3.8A)	1.17A	1zlqA-3hrdD: undetectable	1zlqA-3hrdD: 15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOU_B_CQAB401_0 (HISTAMINE N-METHYLTRANSFERASE)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 7	GLY B  73 PRO B  79 ASP B  80 THR B  93	None	1.09A	2aouB-3hrdB: undetectable	2aouB-3hrdB: 20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_C_SAMC301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	LEU B  61 LEU B 108 GLY B 158 ALA B 100 ALA B  96	None	1.08A	2bm9C-3hrdB: undetectable	2bm9C-3hrdB: 20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C49_A_ADNA1301_1 (SUGAR KINASE MJ0406)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	ALA B  86 GLY B  16 ASN B  22 THR A 318 PHE A 353	NIO  B5661 ( 3.7A) None None None MOS  B 920 (-3.9A)	1.04A	2c49A-3hrdB: undetectable	2c49A-3hrdB: 24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJF_B_ADNB2002_1 (235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 6	GLU A 128 ASN A 149 PRO A 142 ALA A 143	None	1.25A	2ejfB-3hrdA: undetectable	2ejfB-3hrdA: 19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJG_A_ADNA1501_1 (235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 7	GLU A 128 ASN A 149 PRO A 142 ALA A 143	None	1.25A	2ejgA-3hrdA: undetectable	2ejgA-3hrdA: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EJG_B_ADNB1502_1 (235AA LONG HYPOTHETICAL BIOTIN--[ACETYL-COA- CARBOXYLASE] LIGASE)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 7	GLU A 128 ASN A 149 PRO A 142 ALA A 143	None	1.29A	2ejgB-3hrdA: undetectable	2ejgB-3hrdA: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F16_2_BO221405_1 (PROTEASOME COMPONENT PRE3)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 11	THR A 234 THR A 235 ALA A 233 ARG D  30 SER D  37	None	1.21A	2f162-3hrdA: undetectable	2f162-3hrdA: 20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F16_N_BO2N1404_1 (PROTEASOME COMPONENT PRE3)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 11	THR A 234 THR A 235 ALA A 233 ARG D  30 SER D  37	None	1.19A	2f16N-3hrdA: undetectable	2f16N-3hrdA: 20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F78_B_BEZB1002_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR BENM)	3hrd	NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 9	LEU D  29 LEU D  28 ILE D   6 PHE D  33 ILE D  74	None	1.25A	2f78B-3hrdD: undetectable	2f78B-3hrdD: 23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F7A_A_BEZA1003_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR BENM)	3hrd	NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 9	LEU D  29 LEU D  28 ILE D   6 PHE D  33 ILE D  74	None	1.16A	2f7aA-3hrdD: undetectable	2f7aA-3hrdD: 23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FB2_A_SAMA501_0 (MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri; Eubacterium barkeri; Eubacterium barkeri)	4 / 8	CYH D 138 GLU A 187 THR A 234 MET B 219	FES  D 907 ( 2.4A) None None MCN  B 921 (-3.3A)	1.05A	2fb2A-3hrdD: undetectable	2fb2A-3hrdD: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IVU_A_ZD6A3015_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET PRECURSOR)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	3 / 3	ALA A 308 GLY B 247 SER A  44	None	0.56A	2ivuA-3hrdA: undetectable	2ivuA-3hrdA: 22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NPN_A_SAMA4633_0 (PUTATIVE COBALAMIN SYNTHESIS RELATED PROTEIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 9	GLY A  40 ALA A 106 LEU A 253 LEU A  37 THR A 258	None	1.31A	2npnA-3hrdA: undetectable	2npnA-3hrdA: 22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NV4_A_ACTA148_0 (UPF0066 PROTEIN AF_0241)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	3 / 3	VAL C 238 GLU C 234 GLU C 235	None	0.78A	2nv4A-3hrdC: undetectable	2nv4A-3hrdC: 18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PO5_A_CHDA502_0 (FERROCHELATASE, MITOCHONDRIAL)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 8	LEU B 272 PRO B 294 VAL B 228 GLY B 227	None	0.87A	2po5A-3hrdB: undetectable	2po5A-3hrdB: 20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PO5_B_CHDB502_0 (FERROCHELATASE, MITOCHONDRIAL)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 8	LEU B 272 PRO B 294 VAL B 228 GLY B 227	None	0.83A	2po5B-3hrdB: undetectable	2po5B-3hrdB: 20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_A_KLNA1501_1 (CYTOCHROME P450 3A4)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 10	ASP A 376 ILE B 271 LEU A 383 ILE B 224 GLY B   9	None	1.35A	2v0mA-3hrdA: undetectable	2v0mA-3hrdA: 22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V7B_A_BEZA1529_0 (BENZOATE-COENZYME A LIGASE)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	5 / 9	PHE A  27 TYR D 103 GLY D 102 GLY A 237 LYS A  20	None None FES  D 907 (-4.3A) MCN  B 921 (-3.7A) None	1.35A	2v7bA-3hrdA: undetectable	2v7bA-3hrdA: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7K_D_SALD1300_1 (LYSR-TYPE REGULATORY PROTEIN)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	5 / 12	ILE C 199 GLY C 221 GLY C 202 LEU C 282 PHE C 230	None	1.20A	2y7kD-3hrdC: undetectable	2y7kD-3hrdC: 20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGO_A_PCFA1213_1 (WNT INHIBITORY FACTOR 1)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 6	LEU B 292 ILE B 293 PRO B 297 VAL B 242	None	1.07A	2ygoA-3hrdB: undetectable	2ygoA-3hrdB: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGO_A_PCFA1213_1 (WNT INHIBITORY FACTOR 1)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	4 / 6	ILE B  15 ARG A 319 PRO B 290 VAL A 205	None NIO  B5661 (-4.3A) None None	1.08A	2ygoA-3hrdB: undetectable	2ygoA-3hrdB: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AX9_A_SALA1341_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 8	LEU A 245 SER A 246 VAL A 205 ALA A 252	None	0.97A	3ax9A-3hrdA: 15.1	3ax9A-3hrdA: 15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B9M_A_SALA1200_1 (SERUM ALBUMIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 5	ILE A 144 HIS A 145 ARG A  97 GLY A 307	None	1.25A	3b9mA-3hrdA: undetectable	3b9mA-3hrdA: 20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_B_SVRB512_1 (PHOSPHOLIPASE A2)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 5	VAL A 204 VAL A 192 THR A 234 THR A 202	None	1.04A	3bjwA-3hrdA: undetectable	3bjwA-3hrdA: 14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_E_SVRE510_3 (PHOSPHOLIPASE A2)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 5	VAL A 204 VAL A 192 THR A 234 THR A 202	None	1.11A	3bjwG-3hrdA: undetectable	3bjwG-3hrdA: 14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_F_SVRF509_1 (PHOSPHOLIPASE A2)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 5	VAL A 204 VAL A 192 THR A 234 THR A 202	None	1.09A	3bjwC-3hrdA: undetectable	3bjwC-3hrdA: 14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_H_SVRH511_2 (PHOSPHOLIPASE A2)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 5	VAL A 204 VAL A 192 THR A 234 THR A 202	None	1.02A	3bjwD-3hrdA: undetectable	3bjwD-3hrdA: 14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BPX_B_SALB258_1 (TRANSCRIPTIONAL REGULATOR)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 11	ALA A 218 LEU A 221 ILE A  74 PRO A  75 GLY A  76	None	1.23A	3bpxA-3hrdA: undetectable 3bpxB-3hrdA: undetectable	3bpxA-3hrdA: 15.76 3bpxB-3hrdA: 15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BPX_B_SALB258_1 (TRANSCRIPTIONAL REGULATOR)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 11	ALA A 218 LEU A 221 PHE A  80 PRO A  75 GLY A  76	None	1.32A	3bpxA-3hrdA: undetectable 3bpxB-3hrdA: undetectable	3bpxA-3hrdA: 15.76 3bpxB-3hrdA: 15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_I_TRPI1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	3hrd	NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	4 / 8	GLY D  56 ILE D  74 VAL D  52 VAL D  59	None	0.78A	3fi0I-3hrdD: undetectable	3fi0I-3hrdD: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FW1_A_STIA233_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 10	PHE A 239 GLY B 227 GLY B 226 THR B 229 ILE B 268	MCN  B 921 ( 3.6A) None None None None	1.34A	3fw1A-3hrdA: undetectable	3fw1A-3hrdA: 21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3M6V_A_SAMA465_0 (RRNA METHYLASE)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	GLY B 278 GLY B 277 VAL B 287 PRO B 214 LEU B 272	None None MCN  B 921 (-4.2A) None None	1.09A	3m6vA-3hrdB: undetectable	3m6vA-3hrdB: 22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MNO_A_DEXA784_1 (GLUCOCORTICOID RECEPTOR)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 12	GLY D  48 GLN C 104 MET D 108 CYH D 136 ILE B 259	FES  D 908 (-3.8A) None None FES  D 907 (-2.3A) None	1.40A	3mnoA-3hrdD: undetectable	3mnoA-3hrdD: 18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NBQ_B_URFB400_1 (URIDINE PHOSPHORYLASE 1)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 8	GLY A 293 LEU A 369 LEU A 373 ILE A 170	None	0.94A	3nbqB-3hrdA: undetectable	3nbqB-3hrdA: 22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PP1_A_ACTA590_0 (DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 1)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 5	GLU B 289 LEU B 292 GLN B 223 GLY B 227	MOS  B 920 (-2.7A) None MCN  B 921 (-3.0A) None	1.22A	3pp1A-3hrdB: undetectable	3pp1A-3hrdB: 21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RUK_B_AERB601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	ALA B 189 ILE B 316 LEU B 236 ALA B 301 VAL B 235	None	1.06A	3rukB-3hrdB: undetectable	3rukB-3hrdB: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SXJ_A_SAMA258_0 (PUTATIVE METHYLTRANSFERASE)	3hrd	NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 12	ARG D  24 GLY D  45 GLU D  40 ALA D  49 ASN D 134	None FES  D 908 ( 3.2A) None None None	1.29A	3sxjA-3hrdD: undetectable	3sxjA-3hrdD: 20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SXJ_B_SAMB258_0 (PUTATIVE METHYLTRANSFERASE)	3hrd	NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 12	ARG D  24 GLY D  45 GLU D  40 ALA D  49 ASN D 134	None FES  D 908 ( 3.2A) None None None	1.28A	3sxjB-3hrdD: undetectable	3sxjB-3hrdD: 20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3T7S_C_SAMC300_0 (PUTATIVE METHYLTRANSFERASE)	3hrd	NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 12	ARG D  24 GLY D  45 GLU D  40 ALA D  49 ASN D 134	None FES  D 908 ( 3.2A) None None None	1.19A	3t7sC-3hrdD: undetectable	3t7sC-3hrdD: 21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TBG_B_RTZB1_1 (CYTOCHROME P450 2D6)	3hrd	NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 12	LEU D  29 PHE D  33 PHE D  54 ALA D  69 SER D  72	None	1.04A	3tbgB-3hrdD: undetectable	3tbgB-3hrdD: 15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TBG_D_RTZD1_1 (CYTOCHROME P450 2D6)	3hrd	NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 12	LEU D  29 PHE D  33 PHE D  54 ALA D  69 SER D  72	None	1.02A	3tbgD-3hrdD: undetectable	3tbgD-3hrdD: 15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TEG_A_DAHA416_1 (PHENYLALANYL-TRNA SYNTHETASE, MITOCHONDRIAL)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	GLN A 396 THR B 166 GLY B  16 GLY B  19 GLY B  14	None	0.97A	3tegA-3hrdA: undetectable	3tegA-3hrdA: 20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TL9_A_ROCA401_4 (PROTEASE)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 4	ASP A  16 ASP B  44 GLY A 236 THR A 207	None None None MG  A 426 (-3.8A)	1.28A	3tl9B-3hrdA: undetectable	3tl9B-3hrdA: 11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UA1_A_08YA600_1 (CYTOCHROME P450 3A4)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	5 / 12	ARG C 106 SER C  98 THR C 117 PHE C 185 ALA C 195	None None FAD  C 900 (-4.4A) None None	1.30A	3ua1A-3hrdC: undetectable	3ua1A-3hrdC: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UA1_A_08YA600_1 (CYTOCHROME P450 3A4)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	5 / 12	ASP C  35 ARG C 106 SER C  98 PHE C 185 ALA C 195	FAD  C 900 (-3.0A) None None None None	1.37A	3ua1A-3hrdC: undetectable	3ua1A-3hrdC: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UG8_A_IMNA2001_2 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	3 / 3	TYR B 142 GLU B  66 TYR B  65	None	1.02A	3ug8A-3hrdB: undetectable	3ug8A-3hrdB: 20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UJ6_A_SAMA300_1 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 4	SER A 347 ASP A  86 ASP A  93 ALA A 308	None	1.30A	3uj6A-3hrdA: undetectable	3uj6A-3hrdA: 19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WIP_G_ACTG306_0 (ACETYLCHOLINE-BINDIN G PROTEIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	3 / 3	ARG A 266 ARG A  97 ASP A 244	None	0.86A	3wipG-3hrdA: undetectable 3wipH-3hrdA: undetectable	3wipG-3hrdA: 19.63 3wipH-3hrdA: 19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AC9_B_DXCB1473_0 (MJ0495-LIKE PROTEIN)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	5 / 11	ILE C  51 ASP C  52 ILE C  53 SER C 118 GLY C 112	None None None None FAD  C 900 ( 4.3A)	0.75A	4ac9B-3hrdC: undetectable 4ac9C-3hrdC: undetectable	4ac9B-3hrdC: 20.53 4ac9C-3hrdC: 20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B53_B_ACTB1445_0 (IG GAMMA-4 CHAIN C REGION)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	3 / 3	GLU B 225 GLY B 222 SER B 270	None	0.51A	4b53B-3hrdB: undetectable	4b53B-3hrdB: 16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CX7_D_H4BD600_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 7	GLU A 134 MET A 133 ARG A 180 ILE A 130	None	1.45A	4cx7C-3hrdA: undetectable 4cx7D-3hrdA: undetectable	4cx7C-3hrdA: 20.21 4cx7D-3hrdA: 20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FO4_B_MOAB502_1 (INOSINE 5'-MONOPHOSPHATE DEHYDROGENASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	4 / 8	GLY D  45 CYH D  63 THR D  60 GLY C  32	FES  D 908 ( 3.2A) FAD  C 900 ( 3.9A) FES  D 908 (-4.2A) FAD  C 900 (-3.4A)	0.75A	4fo4B-3hrdD: undetectable	4fo4B-3hrdD: 18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J14_A_X2NA602_1 (CHOLESTEROL 24-HYDROXYLASE)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 10	ALA B  25 VAL B  38 ILE B  56 ALA B  57 ALA B 104	None	0.97A	4j14A-3hrdB: undetectable	4j14A-3hrdB: 22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KQI_A_NIOA403_1 (NICOTINATE-NUCLEOTID E--DIMETHYLBENZIMIDA ZOLE PHOSPHORIBOSYLTRANSF ERASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 9	THR D  60 GLY D  45 GLY C 109 LEU C 108 GLY C  33	FES  D 908 (-4.2A) FES  D 908 ( 3.2A) FAD  C 900 ( 3.8A) None FAD  C 900 (-3.3A)	0.95A	4kqiA-3hrdD: undetectable	4kqiA-3hrdD: 21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L78_A_ACTA1327_0 (PHOSPHORIBOSYLFORMYL GLYCINAMIDINE SYNTHASE)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 4	VAL A 274 THR A 273 GLU A 270 GLU A 269	None	1.11A	4l78A-3hrdA: undetectable	4l78A-3hrdA: 15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MMF_A_29QA603_1 (TRANSPORTER)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 9	TYR B  13 GLY A 352 PHE A 353 SER B  87 GLY B  16	None None MOS  B 920 (-3.9A) MCN  B 921 (-4.2A) None	1.27A	4mmfA-3hrdB: undetectable	4mmfA-3hrdB: 22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKV_B_AERB601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	5 / 12	LEU C 163 LEU C 137 GLY C 113 VAL C 135 VAL C 172	FAD  C 900 ( 4.7A) None FAD  C 900 (-3.3A) None None	0.74A	4nkvB-3hrdC: undetectable	4nkvB-3hrdC: 20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKX_B_STRB601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	5 / 12	LEU C 163 GLY C 113 ALA C 133 VAL C 135 VAL C 172	FAD  C 900 ( 4.7A) FAD  C 900 (-3.3A) None None None	0.89A	4nkxB-3hrdC: undetectable	4nkxB-3hrdC: 20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O8F_B_BRLB501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	HIS A 386 VAL A 300 MET A 283 LEU A 404 TYR B 184	None	1.39A	4o8fB-3hrdA: undetectable	4o8fB-3hrdA: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OBW_A_SAMA602_0 (2-METHOXY-6-POLYPREN YL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	ALA B  25 GLY B 160 ILE B  92 ASN B  95 GLY B  81	None	1.22A	4obwA-3hrdB: undetectable	4obwA-3hrdB: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OBW_B_SAMB601_0 (2-METHOXY-6-POLYPREN YL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	ALA B  24 GLY B  81 GLY B  82 GLY B 160 ASN B 163	None	1.05A	4obwB-3hrdB: undetectable	4obwB-3hrdB: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OBW_D_SAMD601_0 (2-METHOXY-6-POLYPREN YL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	ALA B  25 GLY B 160 ILE B  92 ASN B  95 GLY B  81	None	1.21A	4obwD-3hrdB: undetectable	4obwD-3hrdB: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OKB_A_198A1002_1 (ANDROGEN RECEPTOR)	3hrd	NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	5 / 12	GLY D  67 GLN D  68 LEU D  25 THR D  19 ILE D  17	None	1.42A	4okbA-3hrdD: undetectable	4okbA-3hrdD: 18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QOI_B_ML1B303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 11	GLY A 240 GLY A 241 GLY B 288 GLN B  47 ILE B  45	MOS  B 920 ( 3.3A) None MCN  B 921 (-3.6A) MCN  B 921 (-3.8A) MCN  B 921 (-3.9A)	1.19A	4qoiA-3hrdA: undetectable 4qoiB-3hrdA: undetectable	4qoiA-3hrdA: 21.41 4qoiB-3hrdA: 21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QOI_B_ML1B303_1 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 11	GLY B  81 GLY B  82 ILE B  92 GLY B  50 GLN B  47	None None None None MCN  B 921 (-3.8A)	1.18A	4qoiA-3hrdB: undetectable 4qoiB-3hrdB: undetectable	4qoiA-3hrdB: 20.90 4qoiB-3hrdB: 20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVN_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	THR B 187 THR B 186 ALA B 185 GLY B   7 ALA B 298	None	1.23A	4qvnV-3hrdB: undetectable 4qvnb-3hrdB: undetectable	4qvnV-3hrdB: 20.46 4qvnb-3hrdB: 23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVN_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	THR B 187 THR B 186 ALA B 185 GLY B   7 ALA B 298	None	1.23A	4qvnH-3hrdB: undetectable 4qvnN-3hrdB: undetectable	4qvnH-3hrdB: 20.46 4qvnN-3hrdB: 23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW0_K_BO2K301_1 (PROTEASOME SUBUNIT BETA TYPE-5)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 7	ALA B  43 THR B  84 ALA B  83 THR A 207	None MCN  B 921 ( 4.5A) None MG  A 426 (-3.8A)	1.03A	4qw0K-3hrdB: undetectable	4qw0K-3hrdB: 19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QW0_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-5)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 7	ALA B  43 THR B  84 ALA B  83 THR A 207	None MCN  B 921 ( 4.5A) None MG  A 426 (-3.8A)	1.03A	4qw0Y-3hrdB: undetectable	4qw0Y-3hrdB: 19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZDZ_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	4 / 7	PHE C  77 ILE C  80 GLY C 112 LEU C 148	FAD  C 900 (-4.2A) None FAD  C 900 ( 4.3A) None	0.83A	4zdzA-3hrdC: undetectable	4zdzA-3hrdC: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZE3_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	4 / 7	PHE C  77 ILE C  80 GLY C 112 LEU C 148	FAD  C 900 (-4.2A) None FAD  C 900 ( 4.3A) None	0.87A	4ze3A-3hrdC: undetectable	4ze3A-3hrdC: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EQB_A_1YNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	5 / 12	ILE C  30 GLY C  32 GLY C 113 LEU C 163 THR C 143	FAD  C 900 ( 4.7A) FAD  C 900 (-3.4A) FAD  C 900 (-3.3A) FAD  C 900 ( 4.7A) None	1.09A	5eqbA-3hrdC: undetectable	5eqbA-3hrdC: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESF_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	4 / 8	PHE C  77 ILE C  80 GLY C 112 LEU C 148	FAD  C 900 (-4.2A) None FAD  C 900 ( 4.3A) None	0.91A	5esfA-3hrdC: 1.6	5esfA-3hrdC: 18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESJ_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	4 / 8	PHE C  77 ILE C  80 GLY C 112 LEU C 148	FAD  C 900 (-4.2A) None FAD  C 900 ( 4.3A) None	0.84A	5esjA-3hrdC: 1.6	5esjA-3hrdC: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESM_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	4 / 7	PHE C  77 ILE C  80 GLY C 112 LEU C 148	FAD  C 900 (-4.2A) None FAD  C 900 ( 4.3A) None	0.87A	5esmA-3hrdC: undetectable	5esmA-3hrdC: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FSA_A_X2NA590_2 (CYP51 VARIANT1)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	3 / 3	PRO B 297 ILE B 259 SER B  10	None	0.60A	5fsaA-3hrdB: undetectable	5fsaA-3hrdB: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G48_A_1FLA1375_1 (DNA POLYMERASE III SUBUNIT BETA)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	4 / 8	THR C 110 LEU C  74 ILE C  53 LEU C  59	FAD  C 900 (-3.0A) None None None	0.72A	5g48A-3hrdC: undetectable	5g48A-3hrdC: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HP1_C_PPFC601_1 (HIV-1 REVERSE TRANSCRIPTASE P66 SUBUNIT)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 6	ARG A 266 GLY A 241 ASP A 244 LYS A 277	None	1.26A	5hp1C-3hrdA: undetectable	5hp1C-3hrdA: 21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGJ_A_CTYA402_1 (MACROLIDE 2'-PHOSPHOTRANSFERAS E)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	ILE B  30 VAL B  38 ALA B  25 ALA B  26 VAL B  97	None	1.00A	5igjA-3hrdB: undetectable	5igjA-3hrdB: 23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGT_A_ERYA402_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	ILE B  30 VAL B  38 ALA B  25 ALA B  26 VAL B  97	None	1.00A	5igtA-3hrdB: undetectable	5igtA-3hrdB: 23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKQ_A_JMSA602_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	VAL A 247 LEU A 117 VAL A 104 GLY A  40 ALA A  39	None	1.12A	5ikqA-3hrdA: undetectable	5ikqA-3hrdA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKT_A_TLFA601_0 (PROSTAGLANDIN G/H SYNTHASE 2)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	VAL A 247 LEU A 117 VAL A 104 GLY A  40 ALA A  39	None	1.13A	5iktA-3hrdA: undetectable	5iktA-3hrdA: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J4N_A_AG2A501_1 (ARGININE/AGMATINE ANTIPORTER)	3hrd	NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	4 / 6	SER D  37 GLY D  79 ASN D  11 ILE D 109	None	1.07A	5j4nA-3hrdD: undetectable	5j4nA-3hrdD: 18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JWA_H_ACTH614_0 (NADH DEHYDROGENASE, PUTATIVE)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 6	ILE A 150 TYR A 341 VAL A 340 SER A 141	None	0.87A	5jwaH-3hrdA: undetectable	5jwaH-3hrdA: 20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KPC_A_SAMA401_0 (PAVINE N-METHYLTRANSFERASE)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	GLY B  50 GLY B  48 THR B  51 VAL B  70 ALA B  43	None MCN  B 921 (-3.5A) None None None	0.91A	5kpcA-3hrdB: undetectable	5kpcA-3hrdB: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2T_A_6ZZA900_2 (CYCLIN-DEPENDENT KINASE 6)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	3 / 3	LYS C  54 GLN C 104 ASN C 107	None	0.97A	5l2tA-3hrdC: undetectable	5l2tA-3hrdC: 25.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF7_B_6V8B304_0 (PROTEASOME SUBUNIT BETA TYPE-6 PROTEASOME SUBUNIT BETA TYPE-7)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	5 / 12	THR A 234 THR A 235 ALA A 233 ARG D  30 SER D  37	None	1.18A	5lf7V-3hrdA: undetectable 5lf7b-3hrdA: undetectable	5lf7V-3hrdA: 20.68 5lf7b-3hrdA: 20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF7_N_6V8N305_0 (PROTEASOME SUBUNIT BETA TYPE-6 PROTEASOME SUBUNIT BETA TYPE-7)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	5 / 12	THR A 234 THR A 235 ALA A 233 ARG D  30 SER D  37	None	1.16A	5lf7H-3hrdA: undetectable 5lf7N-3hrdA: undetectable	5lf7H-3hrdA: 20.68 5lf7N-3hrdA: 20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_E_Z80E401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	5 / 12	ILE C  86 ILE C  71 VAL C  90 ASN C  67 ALA C 133	None	1.04A	5lg3E-3hrdC: 2.2	5lg3E-3hrdC: 23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M54_B_TA1B502_1 (TUBULIN BETA-2B CHAIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	HIS A 183 ALA A 349 SER A 311 PHE A 353 GLN B  47	None SE  A 922 ( 3.7A) None MOS  B 920 (-3.9A) MCN  B 921 (-3.8A)	1.27A	5m54B-3hrdA: undetectable	5m54B-3hrdA: 22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N0O_B_SAMB501_0 (PEPTIDE N-METHYLTRANSFERASE)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	PHE B 179 VAL B 181 SER B  87 ALA B  86 ALA B  83	None None MCN  B 921 (-4.2A) NIO  B5661 ( 3.7A) None	1.16A	5n0oB-3hrdB: undetectable	5n0oB-3hrdB: 20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NNA_A_BZMA301_0 (ISATIN HYDROLASE A)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	ILE B  30 LEU B 108 GLY B  34 ASP B 127 GLY B 143	None	1.24A	5nnaA-3hrdB: undetectable	5nnaA-3hrdB: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NNA_B_BZMB301_0 (ISATIN HYDROLASE A)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	ILE B  30 LEU B 108 GLY B  34 ASP B 127 GLY B 143	None	1.24A	5nnaB-3hrdB: undetectable	5nnaB-3hrdB: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_A_7V7A201_1 (ENDO-1,4-BETA-XYLANA SE A)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 8	TYR A 176 THR A 178 ARG A 278 GLN A 357	None None NO3  A5658 (-4.0A) NO3  A5658 (-3.1A)	1.15A	5tzoA-3hrdA: undetectable	5tzoA-3hrdA: 17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_B_7V7B202_1 (ENDO-1,4-BETA-XYLANA SE A)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 8	TYR A 176 THR A 178 ARG A 278 GLN A 357	None None NO3  A5658 (-4.0A) NO3  A5658 (-3.1A)	1.12A	5tzoB-3hrdA: undetectable	5tzoB-3hrdA: 17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_C_7V7C202_1 (ENDO-1,4-BETA-XYLANA SE A)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 8	TYR A 176 THR A 178 ARG A 278 GLN A 357	None None NO3  A5658 (-4.0A) NO3  A5658 (-3.1A)	1.08A	5tzoC-3hrdA: undetectable	5tzoC-3hrdA: 17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W97_B_CHDB303_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 2 CYTOCHROME C OXIDASE SUBUNIT 6A2, MITOCHONDRIAL)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 11	GLY A 304 GLN A 357 THR A 321 ARG A 180 GLY A 313	None NO3  A5658 (-3.1A) None None MG  A 427 ( 4.4A)	1.43A	5w97A-3hrdA: 0.0 5w97B-3hrdA: undetectable 5w97g-3hrdA: undetectable	5w97A-3hrdA: 20.89 5w97B-3hrdA: 20.99 5w97g-3hrdA: 12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X19_G_CHDG104_0 (CYTOCHROME C OXIDASE SUBUNIT 1 CYTOCHROME C OXIDASE SUBUNIT 2 CYTOCHROME C OXIDASE SUBUNIT 6A2, MITOCHONDRIAL)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 11	ARG A 180 GLY A 313 GLY A 304 GLN A 357 THR A 321	None MG  A 427 ( 4.4A) None NO3  A5658 (-3.1A) None	1.36A	5x19G-3hrdA: 0.0 5x19N-3hrdA: undetectable 5x19O-3hrdA: 0.0	5x19G-3hrdA: 12.26 5x19N-3hrdA: 20.89 5x19O-3hrdA: 20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X24_A_LSNA503_1 (CYTOCHROME P450 2C9)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 6	PHE B  40 GLY B  94 THR B  93 ASN B  95	None	0.83A	5x24A-3hrdB: undetectable	5x24A-3hrdB: 21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJS_A_SALA603_0 (VICILIN-LIKE ANTIMICROBIAL PEPTIDES 2-2)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	5 / 11	PHE C 230 GLY C 220 MET C 218 MET C 203 GLY C 201	None	0.92A	5yjsA-3hrdC: undetectable	5yjsA-3hrdC: 15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YJS_A_SALA603_0 (VICILIN-LIKE ANTIMICROBIAL PEPTIDES 2-2)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	5 / 11	PHE C 230 GLY C 220 MET C 218 PHE C 283 MET C 203	None	1.34A	5yjsA-3hrdC: undetectable	5yjsA-3hrdC: 15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C2M_C_SUEC1203_1 (NS3 PROTEASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	5 / 9	VAL C  37 GLY C  33 ILE D   4 ARG D  24 ASP D  27	None FAD  C 900 (-3.3A) None None None	1.34A	6c2mC-3hrdC: undetectable	6c2mC-3hrdC: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6C2M_C_SUEC1203_1 (NS3 PROTEASE)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	5 / 9	VAL C  37 GLY C  33 ILE D   6 ARG D  24 ASP D  27	None FAD  C 900 (-3.3A) None None None	0.93A	6c2mC-3hrdC: undetectable	6c2mC-3hrdC: 15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_B_EY4B500_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 6	GLN A 299 VAL A 333 ALA A 393 THR A 394	None	0.93A	6cduB-3hrdA: undetectable 6cduC-3hrdA: undetectable	6cduB-3hrdA: 21.19 6cduC-3hrdA: 21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_D_EY4D500_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 7	GLN A 299 VAL A 333 ALA A 393 THR A 394	None	0.99A	6cduC-3hrdA: undetectable 6cduD-3hrdA: undetectable	6cduC-3hrdA: 21.19 6cduD-3hrdA: 21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6E43_A_BEZA502_0 (INDOLEAMINE 2,3-DIOXYGENASE 1)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	4 / 6	PHE C 230 VAL C 278 LEU C 251 LEU C 254	None	0.98A	6e43A-3hrdC: undetectable	6e43A-3hrdC: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6E43_B_BEZB502_0 (INDOLEAMINE 2,3-DIOXYGENASE 1)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	4 / 6	PHE C 230 VAL C 278 LEU C 251 LEU C 254	None	0.96A	6e43B-3hrdC: undetectable	6e43B-3hrdC: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6E43_C_BEZC502_0 (INDOLEAMINE 2,3-DIOXYGENASE 1)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	4 / 6	PHE C 230 VAL C 278 LEU C 251 LEU C 254	None	0.97A	6e43C-3hrdC: undetectable	6e43C-3hrdC: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6E43_D_BEZD502_0 (INDOLEAMINE 2,3-DIOXYGENASE 1)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	4 / 6	PHE C 230 VAL C 278 LEU C 251 LEU C 254	None	1.02A	6e43D-3hrdC: undetectable	6e43D-3hrdC: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_B_TA1B501_2 (TUBULIN BETA CHAIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 5	LEU B  91 THR B  18 PRO B 290 ARG A 351	None NIO  B5661 (-3.9A) None MCN  B 921 ( 4.0A)	1.10A	6ew0B-3hrdB: undetectable	6ew0B-3hrdB: 14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_D_TA1D501_2 (TUBULIN BETA CHAIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 5	LEU B  91 THR B  18 PRO B 290 ARG A 351	None NIO  B5661 (-3.9A) None MCN  B 921 ( 4.0A)	1.09A	6ew0D-3hrdB: undetectable	6ew0D-3hrdB: 14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_F_TA1F502_2 (TUBULIN BETA CHAIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 5	LEU B  91 THR B  18 PRO B 290 ARG A 351	None NIO  B5661 (-3.9A) None MCN  B 921 ( 4.0A)	1.09A	6ew0F-3hrdB: undetectable	6ew0F-3hrdB: 14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_G_TA1G501_2 (TUBULIN BETA CHAIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 6	LEU B  91 THR B  18 PRO B 290 ARG A 351	None NIO  B5661 (-3.9A) None MCN  B 921 ( 4.0A)	1.10A	6ew0G-3hrdB: undetectable	6ew0G-3hrdB: 14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_H_TA1H501_2 (TUBULIN BETA CHAIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 5	LEU B  91 THR B  18 PRO B 290 ARG A 351	None NIO  B5661 (-3.9A) None MCN  B 921 ( 4.0A)	1.09A	6ew0H-3hrdB: undetectable	6ew0H-3hrdB: 14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_I_TA1I501_2 (TUBULIN BETA CHAIN)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	4 / 5	LEU B  91 THR B  18 PRO B 290 ARG A 351	None NIO  B5661 (-3.9A) None MCN  B 921 ( 4.0A)	1.09A	6ew0I-3hrdB: undetectable	6ew0I-3hrdB: 14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EXI_A_ADNA503_1 (ADENOSYLHOMOCYSTEINA SE)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	3 / 3	LEU A 245 GLN A 248 LYS A  77	None MG  A 426 (-4.2A) None	0.91A	6exiB-3hrdA: undetectable	6exiB-3hrdA: 12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EXI_B_ADNB503_0 (ADENOSYLHOMOCYSTEINA SE)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	3 / 3	LEU A 245 GLN A 248 LYS A  77	None MG  A 426 (-4.2A) None	0.91A	6exiA-3hrdA: undetectable	6exiA-3hrdA: 12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EXI_D_ADND502_1 (ADENOSYLHOMOCYSTEINA SE)	3hrd	NICOTINATE DEHYDROGENASE SMALL FES SUBUNIT (Eubacterium barkeri)	3 / 3	LEU D  25 ASN D  11 LEU D 110	None	0.75A	6exiD-3hrdD: undetectable	6exiD-3hrdD: 18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FBV_D_FI8D1904_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri; Eubacterium barkeri)	4 / 8	ASP B 264 ARG C 191 LYS C 190 GLU B 199	None	1.26A	6fbvD-3hrdB: undetectable	6fbvD-3hrdB: 13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBF_A_ACTA507_0 (MOLYBDOPTERIN BIOSYNTHESIS PROTEIN CNX1)	3hrd	NICOTINATE DEHYDROGENASE LARGE MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	3 / 3	LYS A 242 SER A 275 SER A 271	None	0.94A	6gbfA-3hrdA: undetectable	6gbfA-3hrdA: 25.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HWD_B_BO2B201_0 (PROTEASOME SUBUNIT BETA TYPE-1 PROTEASOME SUBUNIT BETA TYPE-2)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	THR B 187 THR B 186 ALA B 185 GLY B   7 ALA B 298	None	1.21A	6hwdV-3hrdB: undetectable 6hwdb-3hrdB: undetectable	6hwdV-3hrdB: 14.33 6hwdb-3hrdB: 14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HWD_N_BO2N201_0 (PROTEASOME SUBUNIT BETA TYPE-1 PROTEASOME SUBUNIT BETA TYPE-2)	3hrd	NICOTINATE DEHYDROGENASE MEDIUM MOLYBDOPTERIN SUBUNIT (Eubacterium barkeri)	5 / 12	THR B 187 THR B 186 ALA B 185 GLY B   7 ALA B 298	None	1.22A	6hwdH-3hrdB: undetectable 6hwdN-3hrdB: undetectable	6hwdH-3hrdB: 14.33 6hwdN-3hrdB: 14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6IFT_A_SAMA301_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE A)	3hrd	NICOTINATE DEHYDROGENASE FAD-SUBUNIT (Eubacterium barkeri)	5 / 12	ILE C 223 GLY C 220 GLY C 202 ALA C 127 VAL C 258	NO3  C5659 ( 4.8A) None None None None	1.03A	6iftA-3hrdC: undetectable	6iftA-3hrdC: 22.09