SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hrl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YA7_A_ZMRA1776_2 (NEURAMINIDASE A)	3hrl	ENDONUCLEASE-LIKE PROTEIN (Neisseria gonorrhoeae)	4 / 6	ASP A 59 ILE A 68 LEU A 90 TYR A 82	None	1.07A	2ya7A-3hrlA: undetectable	2ya7A-3hrlA: 14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YA7_B_ZMRB1776_2 (NEURAMINIDASE A)	3hrl	ENDONUCLEASE-LIKE PROTEIN (Neisseria gonorrhoeae)	4 / 6	ASP A 59 ILE A 68 LEU A 90 TYR A 82	None	1.07A	2ya7B-3hrlA: undetectable	2ya7B-3hrlA: 14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YA7_D_ZMRD1776_2 (NEURAMINIDASE A)	3hrl	ENDONUCLEASE-LIKE PROTEIN (Neisseria gonorrhoeae)	4 / 6	ASP A 59 ILE A 68 LEU A 90 TYR A 82	None	1.04A	2ya7D-3hrlA: undetectable	2ya7D-3hrlA: 14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HRQ_I_IPHI101_0 (INSULIN A-CHAIN INSULIN B-CHAIN)	3hrl	ENDONUCLEASE-LIKE PROTEIN (Neisseria gonorrhoeae)	4 / 6	VAL A 69 LEU A 98 CYH A 62 LEU A 120	None	1.13A	5hrqB-3hrlA: undetectable 5hrqI-3hrlA: undetectable 5hrqJ-3hrlA: undetectable	5hrqB-3hrlA: 12.50 5hrqI-3hrlA: 12.64 5hrqJ-3hrlA: 12.50

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2YA7_A_ZMRA1776_2","NEURAMINIDASE A","3hrl","ENDONUCLEASE-LIKE PROTEIN","Neisseria gonorrhoeae",4,"ASP A  59;ILE A  68;LEU A  90;TYR A  82","None","1.07A","2ya7A-3hrlA:undetectable","2ya7A-3hrlA:14.04"],["2YA7_B_ZMRB1776_2","NEURAMINIDASE A","3hrl","ENDONUCLEASE-LIKE PROTEIN","Neisseria gonorrhoeae",4,"ASP A  59;ILE A  68;LEU A  90;TYR A  82","None","1.07A","2ya7B-3hrlA:undetectable","2ya7B-3hrlA:14.04"],["2YA7_D_ZMRD1776_2","NEURAMINIDASE A","3hrl","ENDONUCLEASE-LIKE PROTEIN","Neisseria gonorrhoeae",4,"ASP A  59;ILE A  68;LEU A  90;TYR A  82","None","1.04A","2ya7D-3hrlA:undetectable","2ya7D-3hrlA:14.04"],["5HRQ_I_IPHI101_0","INSULIN A-CHAIN;INSULIN B-CHAIN","3hrl","ENDONUCLEASE-LIKE PROTEIN","Neisseria gonorrhoeae",4,"VAL A  69;LEU A  98;CYH A  62;LEU A 120","None","1.13A","5hrqB-3hrlA:undetectable;5hrqI-3hrlA:undetectable;5hrqJ-3hrlA:undetectable","5hrqB-3hrlA:12.50;5hrqI-3hrlA:12.64;5hrqJ-3hrlA:12.50"]]