SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hrt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		5 / 12 VAL A 175
GLY A 176
GLU A  80
ILE A  94
ASP A 160
 None
None
CD  A 501 (-2.7A)
None
CD  A 501 ( 2.9A)
 1.13A 1kxhA-3hrtA:
undetectable		 1kxhA-3hrtA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.66A 1v54C-3hrtA:
undetectable
1v54J-3hrtA:
undetectable		 1v54C-3hrtA:
18.61
1v54J-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.71A 1v54P-3hrtA:
undetectable
1v54W-3hrtA:
undetectable		 1v54P-3hrtA:
18.61
1v54W-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.70A 1v55C-3hrtA:
undetectable
1v55J-3hrtA:
undetectable		 1v55C-3hrtA:
18.61
1v55J-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.75A 1v55P-3hrtA:
undetectable
1v55W-3hrtA:
undetectable		 1v55P-3hrtA:
18.61
1v55W-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 GLU A  80
HIS A  76
ASP A 160
HIS A 125
 CD  A 501 (-2.7A)
None
CD  A 501 ( 2.9A)
CD  A 501 (-4.0A)
 0.89A 1v7zA-3hrtA:
undetectable		 1v7zA-3hrtA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 GLU A  80
HIS A  76
ASP A 160
HIS A 125
 CD  A 501 (-2.7A)
None
CD  A 501 ( 2.9A)
CD  A 501 (-4.0A)
 0.90A 1v7zB-3hrtA:
undetectable		 1v7zB-3hrtA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 GLU A  80
HIS A  76
ASP A 160
HIS A 125
 CD  A 501 (-2.7A)
None
CD  A 501 ( 2.9A)
CD  A 501 (-4.0A)
 0.89A 1v7zC-3hrtA:
undetectable		 1v7zC-3hrtA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 GLU A  80
HIS A  76
ASP A 160
HIS A 125
 CD  A 501 (-2.7A)
None
CD  A 501 ( 2.9A)
CD  A 501 (-4.0A)
 0.90A 1v7zD-3hrtA:
undetectable		 1v7zD-3hrtA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 GLU A  80
HIS A  76
ASP A 160
HIS A 125
 CD  A 501 (-2.7A)
None
CD  A 501 ( 2.9A)
CD  A 501 (-4.0A)
 0.90A 1v7zE-3hrtA:
undetectable		 1v7zE-3hrtA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 GLU A  80
HIS A  76
ASP A 160
HIS A 125
 CD  A 501 (-2.7A)
None
CD  A 501 ( 2.9A)
CD  A 501 (-4.0A)
 0.89A 1v7zF-3hrtA:
undetectable		 1v7zF-3hrtA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.64A 2dyrC-3hrtA:
undetectable
2dyrJ-3hrtA:
undetectable		 2dyrC-3hrtA:
18.61
2dyrJ-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.69A 2dyrP-3hrtA:
undetectable
2dyrW-3hrtA:
undetectable		 2dyrP-3hrtA:
18.61
2dyrW-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.64A 2dysC-3hrtA:
undetectable
2dysJ-3hrtA:
undetectable		 2dysC-3hrtA:
18.61
2dysJ-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.72A 2dysP-3hrtA:
undetectable
2dysW-3hrtA:
undetectable		 2dysP-3hrtA:
18.61
2dysW-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.63A 2eijC-3hrtA:
undetectable
2eijJ-3hrtA:
undetectable		 2eijC-3hrtA:
18.61
2eijJ-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.75A 2eijP-3hrtA:
undetectable
2eijW-3hrtA:
undetectable		 2eijP-3hrtA:
18.61
2eijW-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.77A 2eikP-3hrtA:
undetectable
2eikW-3hrtA:
undetectable		 2eikP-3hrtA:
18.61
2eikW-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.63A 2eilC-3hrtA:
undetectable
2eilJ-3hrtA:
undetectable		 2eilC-3hrtA:
18.61
2eilJ-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.81A 2eimC-3hrtA:
undetectable
2eimJ-3hrtA:
undetectable		 2eimC-3hrtA:
18.61
2eimJ-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.73A 2eimP-3hrtA:
undetectable
2eimW-3hrtA:
undetectable		 2eimP-3hrtA:
18.61
2eimW-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.78A 2einC-3hrtA:
undetectable
2einJ-3hrtA:
undetectable		 2einC-3hrtA:
18.61
2einJ-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.73A 2zxwC-3hrtA:
undetectable
2zxwJ-3hrtA:
undetectable		 2zxwC-3hrtA:
18.61
2zxwJ-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 GLU A  80
HIS A  76
ASP A 160
HIS A 125
 CD  A 501 (-2.7A)
None
CD  A 501 ( 2.9A)
CD  A 501 (-4.0A)
 0.90A 3a6jA-3hrtA:
undetectable		 3a6jA-3hrtA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 GLU A  80
HIS A  76
ASP A 160
HIS A 125
 CD  A 501 (-2.7A)
None
CD  A 501 ( 2.9A)
CD  A 501 (-4.0A)
 0.90A 3a6jB-3hrtA:
undetectable		 3a6jB-3hrtA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 GLU A  80
HIS A  76
ASP A 160
HIS A 125
 CD  A 501 (-2.7A)
None
CD  A 501 ( 2.9A)
CD  A 501 (-4.0A)
 0.93A 3a6jC-3hrtA:
undetectable		 3a6jC-3hrtA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 GLU A  80
HIS A  76
ASP A 160
HIS A 125
 CD  A 501 (-2.7A)
None
CD  A 501 ( 2.9A)
CD  A 501 (-4.0A)
 0.92A 3a6jE-3hrtA:
undetectable		 3a6jE-3hrtA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 8 GLU A  80
HIS A  76
ASP A 160
HIS A 125
 CD  A 501 (-2.7A)
None
CD  A 501 ( 2.9A)
CD  A 501 (-4.0A)
 0.90A 3a6jF-3hrtA:
undetectable		 3a6jF-3hrtA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.71A 3asnP-3hrtA:
undetectable
3asnW-3hrtA:
undetectable		 3asnP-3hrtA:
18.61
3asnW-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.73A 3asoP-3hrtA:
undetectable
3asoW-3hrtA:
undetectable		 3asoP-3hrtA:
18.61
3asoW-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FUB_A_ACTA311_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		3 / 3 TYR A  73
ARG A 157
HIS A 159
 None
SO4  A 250 (-4.0A)
SO4  A 250 (-3.7A)
 0.94A 4fubA-3hrtA:
undetectable		 4fubA-3hrtA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.73A 5b3sP-3hrtA:
undetectable		 5b3sP-3hrtA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F8Y_A_X6XA202_1
(GALNAC/GAL-SPECIFIC
LECTIN)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		5 / 8 GLY A 126
GLY A 127
VAL A 175
HIS A 125
ASP A 160
 None
None
None
CD  A 501 (-4.0A)
CD  A 501 ( 2.9A)
 1.35A 5f8yA-3hrtA:
undetectable		 5f8yA-3hrtA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_K_IPHK101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 6 VAL A  84
HIS A  85
CYH A 123
HIS A  86
 None
None
CD  A 501 (-2.5A)
None
 1.44A 5hrqH-3hrtA:
undetectable
5hrqK-3hrtA:
undetectable
5hrqL-3hrtA:
undetectable		 5hrqH-3hrtA:
9.35
5hrqK-3hrtA:
9.52
5hrqL-3hrtA:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 6 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.69A 5w97C-3hrtA:
undetectable
5w97J-3hrtA:
undetectable		 5w97C-3hrtA:
18.61
5w97J-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 6 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.66A 5x19P-3hrtA:
undetectable		 5x19P-3hrtA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		4 / 7 ARG A  74
LYS A  75
LEU A  78
PHE A  82
 None
 0.68A 5x1fP-3hrtA:
undetectable
5x1fW-3hrtA:
undetectable		 5x1fP-3hrtA:
18.61
5x1fW-3hrtA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hrt METALLOREGULATOR
SCAR
(Streptococcus
gordonii) 		3 / 3 ARG A  74
LEU A  78
PHE A  82
 None
 0.29A 6nknP-3hrtA:
undetectable		 6nknP-3hrtA:
18.61