SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hrv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 3hrv TOXIN COREGULATED
PILIN
(Vibrio
cholerae) 		4 / 7 SER A  53
ARG A  52
TYR A  51
LEU A  54
 None
GOL  A1002 (-3.1A)
None
None
 1.11A 1ibgL-3hrvA:
undetectable		 1ibgL-3hrvA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrv TOXIN COREGULATED
PILIN
(Vibrio
cholerae) 		4 / 5 PHE A 150
PHE A  98
LEU A 147
PHE A 141
 None
 1.33A 2y69C-3hrvA:
undetectable
2y69J-3hrvA:
undetectable		 2y69C-3hrvA:
20.00
2y69J-3hrvA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrv TOXIN COREGULATED
PILIN
(Vibrio
cholerae) 		4 / 5 PHE A 150
PHE A  98
LEU A 147
PHE A 141
 None
 1.34A 3abmC-3hrvA:
undetectable
3abmJ-3hrvA:
undetectable		 3abmC-3hrvA:
20.00
3abmJ-3hrvA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hrv TOXIN COREGULATED
PILIN
(Vibrio
cholerae) 		4 / 5 PHE A 150
PHE A  98
LEU A 147
PHE A 141
 None
 1.33A 3abmP-3hrvA:
undetectable
3abmW-3hrvA:
undetectable		 3abmP-3hrvA:
20.00
3abmW-3hrvA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 3hrv TOXIN COREGULATED
PILIN
(Vibrio
cholerae) 		4 / 4 THR A 125
VAL A 194
GLY A 160
THR A 159
 None
 1.09A 3cflA-3hrvA:
undetectable		 3cflA-3hrvA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 3hrv TOXIN COREGULATED
PILIN
(Vibrio
cholerae) 		5 / 9 GLY A 160
ALA A 157
ASP A 156
ILE A 179
LEU A 174
 None
 1.03A 3ogpB-3hrvA:
undetectable		 3ogpB-3hrvA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hrv TOXIN COREGULATED
PILIN
(Vibrio
cholerae) 		4 / 5 PHE A 150
PHE A  98
LEU A 147
PHE A 141
 None
 1.32A 5wauc-3hrvA:
undetectable
5wauj-3hrvA:
undetectable		 5wauc-3hrvA:
20.00
5wauj-3hrvA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hrv TOXIN COREGULATED
PILIN
(Vibrio
cholerae) 		4 / 5 PHE A 150
PHE A  98
LEU A 147
PHE A 141
 None
 1.31A 5xdqC-3hrvA:
undetectable
5xdqJ-3hrvA:
undetectable		 5xdqC-3hrvA:
20.00
5xdqJ-3hrvA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hrv TOXIN COREGULATED
PILIN
(Vibrio
cholerae) 		4 / 5 PHE A 150
PHE A  98
LEU A 147
PHE A 141
 None
 1.32A 5xdqP-3hrvA:
undetectable
5xdqW-3hrvA:
undetectable		 5xdqP-3hrvA:
20.00
5xdqW-3hrvA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 3hrv TOXIN COREGULATED
PILIN
(Vibrio
cholerae) 		4 / 9 PHE A 192
VAL A 154
SER A 153
ASP A 156
 None
 0.82A 6c2mD-3hrvA:
undetectable		 6c2mD-3hrvA:
17.71