SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hs0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 GLN B 847
ILE B 813
HIS B 815
 None
 0.74A 1fm9A-3hs0B:
undetectable		 1fm9A-3hs0B:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 GLN B 847
ILE B 813
HIS B 815
 None
 0.70A 1k74A-3hs0B:
undetectable		 1k74A-3hs0B:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 11 PHE B 717
PHE B 792
LEU B 814
VAL B 858
PHE B 860
 None
 1.33A 1q23L-3hs0B:
undetectable		 1q23L-3hs0B:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 ASP A 157
LEU A 158
HIS A 183
 None
 0.73A 1qknA-3hs0A:
undetectable		 1qknA-3hs0A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 11 LEU A 460
GLY A 603
ALA A 602
GLY A 597
VAL A 499
 None
 0.80A 1t7jA-3hs0A:
undetectable		 1t7jA-3hs0A:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0G_A_MYTA1499_1
(CYTOCHROME P450 3A4)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 SER B 725
ILE B 723
ALA B 876
ALA B 812
 None
 0.99A 1w0gA-3hs0B:
undetectable		 1w0gA-3hs0B:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 5 PRO C1452
LEU C1341
GLY C1339
LYS C1422
 None
 1.44A 1ya4C-3hs0C:
undetectable		 1ya4C-3hs0C:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 8 ILE C1345
PHE C1418
LEU C1378
ILE C1386
 None
 0.86A 2azxA-3hs0C:
undetectable		 2azxA-3hs0C:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H9T_H_SVRH301_1
(THROMBIN)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 11 TRP B 883
LYS B 790
VAL B 791
GLY A 232
GLU A 234
 None
 1.34A 2h9tH-3hs0B:
undetectable		 2h9tH-3hs0B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 4 VAL A  61
THR A  62
VAL A 470
GLY A 471
 None
 1.15A 2p2fB-3hs0A:
undetectable		 2p2fB-3hs0A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 3hs0 COBRA VENOM FACTOR
COBRA VENOM FACTOR
(Naja
kaouthia;
Naja
kaouthia) 		4 / 6 MET A 299
ILE C1359
PRO A 200
SER A 201
 None
 1.48A 2qd3B-3hs0A:
undetectable		 2qd3B-3hs0A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 LEU A 166
PRO A 167
ARG A 195
 None
 0.58A 2qd5A-3hs0A:
undetectable		 2qd5A-3hs0A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		6 / 11 ALA A 374
LEU A 376
ILE A 323
ILE A 389
PHE A 325
THR A 368
 None
 1.38A 2w9sA-3hs0A:
undetectable		 2w9sA-3hs0A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		6 / 11 ALA A 374
LEU A 376
ILE A 323
ILE A 389
PHE A 325
THR A 368
 None
 1.33A 2w9sB-3hs0A:
undetectable		 2w9sB-3hs0A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		6 / 10 ALA A 374
LEU A 376
ILE A 323
ILE A 389
PHE A 325
THR A 368
 None
 1.33A 2w9sC-3hs0A:
undetectable		 2w9sC-3hs0A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_D_TOPD1158_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 10 ALA A 374
LEU A 376
ILE A 323
PHE A 325
THR A 368
 None
 1.21A 2w9sD-3hs0A:
undetectable		 2w9sD-3hs0A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 10 ALA A 374
LEU A 376
ILE A 323
PHE A 325
THR A 368
 None
 1.20A 2w9sF-3hs0A:
undetectable		 2w9sF-3hs0A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF6_H_SVRH301_1
(THROMBIN, HEAVY
CHAIN)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 11 TRP B 883
LYS B 790
VAL B 791
GLY A 232
GLU A 234
 None
 1.39A 3bf6H-3hs0B:
undetectable		 3bf6H-3hs0B:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 5 VAL A 391
VAL A 358
THR A 405
ARG A 392
 None
 1.18A 3bjwA-3hs0A:
undetectable		 3bjwA-3hs0A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 5 VAL A 391
VAL A 358
THR A 405
ARG A 392
 None
 1.20A 3bjwC-3hs0A:
undetectable		 3bjwC-3hs0A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 10 LEU A 460
GLY A 603
ALA A 602
GLY A 597
LEU A 596
 None
 0.89A 3em3A-3hs0A:
undetectable		 3em3A-3hs0A:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRE_X_TOPX300_1
(DIHYDROFOLATE
REDUCTASE)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 9 ALA A 374
LEU A 376
ILE A 389
PHE A 325
THR A 368
 None
 1.26A 3freX-3hs0A:
undetectable		 3freX-3hs0A:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 GLU A  22
HIS A  24
THR A 458
 None
 0.80A 3hkuA-3hs0A:
undetectable		 3hkuA-3hs0A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 11 VAL A 564
VAL A 307
LEU A 230
THR B 764
THR B 763
 None
 1.27A 3iaiA-3hs0A:
undetectable		 3iaiA-3hs0A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 11 VAL A 564
VAL A 307
LEU A 230
THR B 764
THR B 763
 None
 1.28A 3iaiB-3hs0A:
undetectable		 3iaiB-3hs0A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 11 VAL A 564
VAL A 307
LEU A 230
THR B 764
THR B 763
 None
 1.27A 3iaiC-3hs0A:
undetectable		 3iaiC-3hs0A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 11 VAL A 564
VAL A 307
LEU A 230
THR B 764
THR B 763
 None
 1.26A 3iaiD-3hs0A:
undetectable		 3iaiD-3hs0A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 10 GLY A 266
ALA A 227
VAL A 307
VAL A 296
VAL A 298
 None
 1.11A 3nu9B-3hs0A:
undetectable		 3nu9B-3hs0A:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 ALA A 551
SER B 771
VAL A 553
LEU B 740
 None
 0.82A 3o14A-3hs0A:
undetectable		 3o14A-3hs0A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 9 LEU A 460
GLY A 603
ALA A 602
GLY A 597
VAL A 499
 None
 0.77A 3u7sA-3hs0A:
undetectable		 3u7sA-3hs0A:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 5 GLY A 592
VAL A 598
ASP A 601
THR A 588
 None
 1.03A 3vqrB-3hs0A:
undetectable		 3vqrB-3hs0A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 PHE C1428
ALA B 837
GLY C1472
LEU C1459
 None
 0.88A 4dubA-3hs0C:
undetectable		 4dubA-3hs0C:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 PHE C1428
ALA B 837
GLY C1472
LEU C1459
 None
 0.92A 4dubB-3hs0C:
undetectable		 4dubB-3hs0C:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 LEU A 565
TYR A 563
LYS A 560
GLU A 203
 None
 1.12A 4f3tA-3hs0A:
undetectable		 4f3tA-3hs0A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA408_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 3hs0 COBRA VENOM FACTOR
COBRA VENOM FACTOR
(Naja
kaouthia;
Naja
kaouthia) 		4 / 6 THR C1366
PHE B 848
ARG B 856
PHE B 860
 None
 1.28A 4kf9A-3hs0C:
undetectable		 4kf9A-3hs0C:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 4 ILE A 580
SER A 583
ASP A 520
ASP A 371
 None
None
MG  A 628 (-2.7A)
None
 1.29A 4krhB-3hs0A:
undetectable		 4krhB-3hs0A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XOY_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 ALA C1340
LYS C1338
LEU C1341
MET C1342
 None
 1.14A 4xoyA-3hs0C:
undetectable		 4xoyA-3hs0C:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP3_A_DX4A401_0
(MITOGEN-ACTIVATED
PROTEIN KINASE 1)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 ALA C1340
LYS C1338
LEU C1341
MET C1342
 None
 1.18A 4xp3A-3hs0C:
undetectable		 4xp3A-3hs0C:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 LEU A 565
TYR A 563
LYS A 560
GLU A 203
 None
 1.09A 4z4gA-3hs0A:
undetectable		 4z4gA-3hs0A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 THR A 579
ILE A 580
SER A 583
PHE A 585
 None
 0.50A 5fukA-3hs0A:
undetectable
5fukB-3hs0A:
undetectable		 5fukA-3hs0A:
17.92
5fukB-3hs0A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 12 LEU C1323
VAL C1408
LEU C1378
ILE C1403
LEU C1405
 None
 1.07A 5ienA-3hs0C:
undetectable		 5ienA-3hs0C:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 3hs0 COBRA VENOM FACTOR
COBRA VENOM FACTOR
(Naja
kaouthia;
Naja
kaouthia) 		4 / 8 TYR A 164
THR C1280
PRO A 146
ILE A 149
 None
 1.07A 5jhdE-3hs0A:
5.4
5jhdG-3hs0A:
4.8		 5jhdE-3hs0A:
16.69
5jhdG-3hs0A:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 ILE C1360
TYR C1437
VAL C1436
SER C1355
 None
 0.99A 5jwaH-3hs0C:
undetectable		 5jwaH-3hs0C:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3hs0 COBRA VENOM FACTOR
COBRA VENOM FACTOR
(Naja
kaouthia;
Naja
kaouthia) 		5 / 12 ILE B 941
TYR C1268
ILE C1255
MET C1301
VAL C1291
 None
 0.96A 5n0sA-3hs0B:
undetectable		 5n0sA-3hs0B:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3hs0 COBRA VENOM FACTOR
COBRA VENOM FACTOR
(Naja
kaouthia;
Naja
kaouthia) 		5 / 12 ILE B 941
TYR C1268
ILE C1255
MET C1301
VAL C1291
 None
 1.04A 5n0tA-3hs0B:
undetectable		 5n0tA-3hs0B:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3hs0 COBRA VENOM FACTOR
COBRA VENOM FACTOR
(Naja
kaouthia;
Naja
kaouthia) 		5 / 12 ILE B 941
TYR C1268
ILE C1255
MET C1301
VAL C1291
 None
 1.07A 5n0tB-3hs0B:
undetectable		 5n0tB-3hs0B:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 4 TYR A 502
SER A 450
GLN A 416
THR A 415
 None
 1.31A 5n0tB-3hs0A:
0.0		 5n0tB-3hs0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3hs0 COBRA VENOM FACTOR
COBRA VENOM FACTOR
(Naja
kaouthia;
Naja
kaouthia) 		5 / 12 ILE B 941
TYR C1268
ILE C1255
MET C1301
VAL C1291
 None
 1.06A 5n0wB-3hs0B:
undetectable		 5n0wB-3hs0B:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3hs0 COBRA VENOM FACTOR
COBRA VENOM FACTOR
(Naja
kaouthia;
Naja
kaouthia) 		5 / 12 ILE B 941
TYR C1268
ILE C1255
MET C1301
VAL C1291
 None
 1.06A 5n0xA-3hs0B:
undetectable		 5n0xA-3hs0B:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3hs0 COBRA VENOM FACTOR
COBRA VENOM FACTOR
(Naja
kaouthia;
Naja
kaouthia) 		5 / 12 ILE B 941
TYR C1268
ILE C1255
MET C1301
VAL C1291
 None
 1.04A 5n4iA-3hs0B:
undetectable		 5n4iA-3hs0B:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 VAL A 344
TYR A 321
GLN A 322
 None
 0.62A 5qgkA-3hs0A:
undetectable		 5qgkA-3hs0A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 VAL A 344
TYR A 321
GLN A 322
 None
 0.59A 5qgrA-3hs0A:
undetectable		 5qgrA-3hs0A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 VAL A 344
TYR A 321
GLN A 322
 None
 0.63A 5qgtA-3hs0A:
undetectable		 5qgtA-3hs0A:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_A_SALA505_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 8 SER B 838
PHE B 860
GLN B 846
THR C1366
 None
 1.22A 5u6nA-3hs0B:
undetectable		 5u6nA-3hs0B:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		5 / 12 LEU A 158
TYR A 181
ASP A  14
PRO A  68
GLU A  71
 None
 1.36A 5x6yC-3hs0A:
undetectable		 5x6yC-3hs0A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 GLN B 847
ILE B 813
HIS B 815
 None
 0.65A 5z12B-3hs0B:
undetectable		 5z12B-3hs0B:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_0
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 3hs0 COBRA VENOM FACTOR
COBRA VENOM FACTOR
(Naja
kaouthia;
Naja
kaouthia) 		5 / 12 GLU A 236
GLY A 237
TYR C1389
ALA A 227
ALA A 239
 None
 1.03A 5zw4A-3hs0A:
undetectable		 5zw4A-3hs0A:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 5 ASN A 595
VAL A 444
LEU A 451
SER A 419
 None
 1.26A 6a7pA-3hs0A:
undetectable		 6a7pA-3hs0A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		3 / 3 TYR C1500
HIS C1539
MET C1520
 None
 1.18A 6af6A-3hs0C:
undetectable		 6af6A-3hs0C:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 6 TYR A 338
ASP A 512
VAL A 425
ALA A 410
 None
 1.25A 6djzB-3hs0A:
undetectable		 6djzB-3hs0A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 3hs0 COBRA VENOM FACTOR
(Naja
kaouthia) 		4 / 7 ARG C1587
HIS C1590
LEU C1507
TYR C1559
 None
 1.27A 6g2pA-3hs0C:
undetectable		 6g2pA-3hs0C:
21.76