SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ht1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3ht1 REMF PROTEIN
(Streptomyces
resistomycificus) 		4 / 8 PHE A 107
HIS A  59
HIS A  55
HIS A  53
 None
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
 0.97A 1bzmA-3ht1A:
undetectable		 1bzmA-3ht1A:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 3ht1 REMF PROTEIN
(Streptomyces
resistomycificus) 		3 / 3 HIS A  55
HIS A  95
HIS A  59
 NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
 0.52A 3qpkA-3ht1A:
undetectable		 3qpkA-3ht1A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 3ht1 REMF PROTEIN
(Streptomyces
resistomycificus) 		3 / 3 HIS A  55
HIS A  95
HIS A  59
 NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
 0.47A 3qpkB-3ht1A:
undetectable		 3qpkB-3ht1A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)		 3ht1 REMF PROTEIN
(Streptomyces
resistomycificus) 		4 / 4 HIS A  95
HIS A  59
HIS A  53
HIS A  55
 NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
 1.12A 4ef3A-3ht1A:
undetectable		 4ef3A-3ht1A:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 3ht1 REMF PROTEIN
(Streptomyces
resistomycificus) 		3 / 3 HIS A  55
HIS A  95
HIS A  59
 NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
 0.52A 5migA-3ht1A:
undetectable		 5migA-3ht1A:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 3ht1 REMF PROTEIN
(Streptomyces
resistomycificus) 		4 / 5 HIS A  55
HIS A  53
HIS A  95
HIS A  59
 NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
 0.96A 5zrdB-3ht1A:
undetectable		 5zrdB-3ht1A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 3ht1 REMF PROTEIN
(Streptomyces
resistomycificus) 		4 / 4 HIS A  55
HIS A  53
HIS A  95
HIS A  59
 NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
 0.93A 5zrdC-3ht1A:
undetectable		 5zrdC-3ht1A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 3ht1 REMF PROTEIN
(Streptomyces
resistomycificus) 		4 / 4 HIS A  95
HIS A  59
HIS A  55
HIS A  53
 NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
 1.17A 5zrdC-3ht1A:
undetectable		 5zrdC-3ht1A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 3ht1 REMF PROTEIN
(Streptomyces
resistomycificus) 		4 / 4 HIS A  55
HIS A  53
HIS A  95
HIS A  59
 NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
 0.93A 5zrdD-3ht1A:
undetectable		 5zrdD-3ht1A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 3ht1 REMF PROTEIN
(Streptomyces
resistomycificus) 		4 / 4 HIS A  95
HIS A  59
HIS A  55
HIS A  53
 NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
 1.17A 5zrdD-3ht1A:
undetectable		 5zrdD-3ht1A:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EFN_A_SAMA501_0
(SPORULATION KILLING
FACTOR MATURATION
PROTEIN SKFB)		 3ht1 REMF PROTEIN
(Streptomyces
resistomycificus) 		5 / 11 THR A 104
GLU A  21
ALA A  11
THR A  40
LEU A 108
 None
 1.34A 6efnA-3ht1A:
undetectable		 6efnA-3ht1A:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ht1 REMF PROTEIN
(Streptomyces
resistomycificus) 		3 / 3 HIS A  55
HIS A  95
HIS A  53
 NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
NI  A 151 (-3.3A)
 0.72A 6giqa-3ht1A:
undetectable		 6giqa-3ht1A:
14.81