SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ht4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 9 LEU A 121
GLY A 102
ILE A 103
VAL A 125
ILE A 124
 None
 0.86A 1ohrB-3ht4A:
undetectable		 1ohrB-3ht4A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 LEU A 307
LEU A 304
ALA A 301
VAL A 394
ILE A  14
 None
 1.05A 1s9pD-3ht4A:
undetectable		 1s9pD-3ht4A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 ALA A 344
PHE A 303
ILE A 411
ASP A 412
LYS A 404
 None
 1.07A 2v95A-3ht4A:
undetectable		 2v95A-3ht4A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		4 / 7 LEU A 100
LEU A 104
PHE A 135
LEU A 121
 None
 0.74A 2vq5B-3ht4A:
undetectable		 2vq5B-3ht4A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		4 / 7 LEU A  84
GLU A  71
ASP A  68
THR A 261
 None
 1.38A 3dzgB-3ht4A:
undetectable		 3dzgB-3ht4A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		4 / 8 GLY A 396
ILE A 405
CYH A 408
PHE A 337
 None
 0.96A 3ko0O-3ht4A:
0.0
3ko0Q-3ht4A:
0.8		 3ko0O-3ht4A:
12.23
3ko0Q-3ht4A:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 238
GLY A 236
THR A 399
LEU A 398
SER A 230
 None
 1.25A 3mteA-3ht4A:
undetectable		 3mteA-3ht4A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 LEU A 260
TYR A 245
ARG A  86
GLY A 229
LEU A  84
 None
 1.30A 3okxA-3ht4A:
undetectable		 3okxA-3ht4A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1004_1
(HEMOLYTIC LECTIN
CEL-III)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		4 / 4 ASP A 321
GLY A 176
TYR A 210
GLN A 395
 None
 1.13A 3w9tC-3ht4A:
0.0		 3w9tC-3ht4A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD506_1
(HEMOLYTIC LECTIN
CEL-III)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		4 / 5 ASP A 321
GLY A 176
TYR A 210
GLN A 395
 None
 1.00A 3w9tD-3ht4A:
undetectable		 3w9tD-3ht4A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE505_1
(HEMOLYTIC LECTIN
CEL-III)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		4 / 5 ASP A 321
GLY A 176
TYR A 210
GLN A 395
 None
 1.08A 3w9tE-3ht4A:
undetectable		 3w9tE-3ht4A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG505_1
(HEMOLYTIC LECTIN
CEL-III)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		4 / 5 ASP A 321
GLY A 176
TYR A 210
GLN A 395
 None
 1.02A 3w9tG-3ht4A:
undetectable		 3w9tG-3ht4A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 LEU A 121
GLY A 102
ILE A 103
VAL A 125
ILE A 124
 None
 0.94A 4dqfA-3ht4A:
undetectable		 4dqfA-3ht4A:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOT_A_CE3A205_1
(UNCHARACTERIZED
PROTEIN)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 PHE A 213
PRO A 235
GLY A 244
ILE A 246
PHE A  78
 None
 1.34A 4kotA-3ht4A:
undetectable		 4kotA-3ht4A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX6_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 ALA A 267
LYS A 249
THR A  98
LEU A 226
ILE A 246
 None
 1.08A 4nx6A-3ht4A:
undetectable		 4nx6A-3ht4A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 ALA A 267
LYS A 249
THR A  98
LEU A 226
ILE A 246
 None
 1.07A 4nx7A-3ht4A:
undetectable		 4nx7A-3ht4A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QE6_A_JN3A1001_1
(BILE ACID RECEPTOR)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 ALA A 369
SER A 377
ILE A 378
TYR A 177
TYR A 210
 None
 1.19A 4qe6A-3ht4A:
0.0		 4qe6A-3ht4A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 11 LEU A 121
GLY A 102
ILE A 103
VAL A 125
ILE A 124
 None
 0.91A 4qgiB-3ht4A:
undetectable		 4qgiB-3ht4A:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 11 GLY A 236
GLY A 237
ILE A 378
GLY A 229
PHE A  78
 None
 1.13A 4qoiA-3ht4A:
2.1
4qoiB-3ht4A:
2.2		 4qoiA-3ht4A:
21.43
4qoiB-3ht4A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A  83
PHE A  78
GLY A 229
LEU A 231
PRO A 235
 None
 1.15A 4uilH-3ht4A:
undetectable
4uilL-3ht4A:
undetectable		 4uilH-3ht4A:
20.00
4uilL-3ht4A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 VAL A  85
GLY A  66
ILE A  55
SER A  52
HIS A  53
 None
 1.27A 4xudA-3ht4A:
3.7		 4xudA-3ht4A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 10 GLY A 126
GLU A 123
SER A  97
GLY A 133
SER A 134
 None
 1.03A 5aqfA-3ht4A:
undetectable		 5aqfA-3ht4A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 10 GLY A 126
GLU A 123
SER A  97
GLY A 133
SER A 134
 None
 1.04A 5aqfC-3ht4A:
undetectable		 5aqfC-3ht4A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A 378
GLY A 237
ALA A 290
PHE A  78
LEU A 322
 None
 1.24A 5hw4C-3ht4A:
1.0		 5hw4C-3ht4A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 GLY A 211
THR A 320
ALA A 293
LEU A 294
ALA A 297
 None
 0.97A 5kpcA-3ht4A:
undetectable		 5kpcA-3ht4A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A 198
PHE A 194
VAL A 202
THR A 166
GLU A 109
 None
 1.11A 5lg3E-3ht4A:
undetectable		 5lg3E-3ht4A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_J_Z80J401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		5 / 12 ILE A 198
PHE A 194
VAL A 202
THR A 166
GLU A 109
 None
 1.14A 5lg3J-3ht4A:
undetectable		 5lg3J-3ht4A:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		4 / 8 PHE A 213
PHE A 283
VAL A 247
TYR A 245
 None
 1.16A 6huoC-3ht4A:
undetectable
6huoD-3ht4A:
undetectable		 6huoC-3ht4A:
10.93
6huoD-3ht4A:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_C_LLLC301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3ht4 ALUMINUM RESISTANCE
PROTEIN
(Bacillus
cereus) 		4 / 6 ASP A 207
TYR A 245
GLU A 212
GLU A 215
 None
 1.43A 6mn5C-3ht4A:
undetectable		 6mn5C-3ht4A:
12.02