SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3htm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 3htm SPECKLE-TYPE POZ
PROTEIN
(Homo
sapiens) 		4 / 6 LEU A 266
ASP A 271
LEU A 308
HIS A 312
 None
 1.07A 3bj8C-3htmA:
undetectable
3bj8D-3htmA:
undetectable		 3bj8C-3htmA:
20.63
3bj8D-3htmA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 3htm SPECKLE-TYPE POZ
PROTEIN
(Homo
sapiens) 		3 / 3 MET A 255
MET A 288
TYR A 280
 None
 1.25A 4p6xI-3htmA:
undetectable		 4p6xI-3htmA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 3htm SPECKLE-TYPE POZ
PROTEIN
(Homo
sapiens) 		3 / 3 ILE A 217
MET A 228
ASP A 201
 None
 0.84A 5h2uA-3htmA:
undetectable		 5h2uA-3htmA:
22.99