SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3htv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		5 / 12 LEU A  98
LEU A 106
LEU A  67
MET A  13
PHE A  71
 None
 1.41A 1d4fA-3htvA:
undetectable		 1d4fA-3htvA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		5 / 12 LEU A  98
LEU A 106
LEU A  67
MET A  13
PHE A  71
 None
 1.43A 1d4fB-3htvA:
undetectable		 1d4fB-3htvA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_C_THAC3_1
(LIVER
CARBOXYLESTERASE I)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		5 / 12 LEU A  90
VAL A 110
LEU A  67
LEU A 102
LEU A  95
 None
 1.19A 1mx1C-3htvA:
undetectable		 1mx1C-3htvA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_C_MTXC353_1
(PTERIDINE REDUCTASE
1)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		5 / 12 SER A  76
PHE A 112
LEU A 102
LEU A  90
LEU A  88
 None
 1.42A 1p33C-3htvA:
undetectable		 1p33C-3htvA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		4 / 7 MET A 249
ALA A 137
ARG A 228
GLU A 185
 None
 1.14A 1t9wA-3htvA:
undetectable		 1t9wA-3htvA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		3 / 3 ARG A 228
TYR A 266
LYS A 265
 None
 1.01A 1uujB-3htvA:
undetectable		 1uujB-3htvA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		4 / 7 PHE A  20
LEU A  22
LEU A  30
GLU A  51
 None
 1.02A 2jn3A-3htvA:
undetectable		 2jn3A-3htvA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		4 / 7 VAL A 125
ASN A 287
GLY A 288
ASP A 115
 None
 0.95A 2y05A-3htvA:
undetectable
2y05B-3htvA:
undetectable		 2y05A-3htvA:
22.70
2y05B-3htvA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_0
(N,N-DIMETHYLTRANSFER
ASE)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		5 / 12 ALA A 293
GLY A  10
HIS A  31
LEU A 295
PHE A 286
 None
 1.42A 3bxoB-3htvA:
undetectable		 3bxoB-3htvA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_A_SAMA770_0
(23S RRNA
METHYLTRANSFERASE)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		5 / 12 LEU A 120
GLY A 291
GLY A 288
ILE A 243
SER A 282
 None
 0.89A 3nk7A-3htvA:
undetectable		 3nk7A-3htvA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		5 / 12 ALA A 293
GLY A  10
HIS A  31
LEU A 295
PHE A 286
 None
 1.38A 3pfgA-3htvA:
undetectable		 3pfgA-3htvA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		4 / 6 LEU A 139
VAL A 248
MET A 251
PHE A 210
 None
 1.11A 3soaA-3htvA:
undetectable		 3soaA-3htvA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		5 / 12 LEU A 106
LEU A 102
LEU A  98
ILE A  53
VAL A  40
 None
 1.14A 4f4dA-3htvA:
undetectable		 4f4dA-3htvA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		5 / 12 LEU A 106
LEU A 102
LEU A  98
ILE A  53
VAL A  40
 None
 1.16A 4f4dB-3htvA:
undetectable		 4f4dB-3htvA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA206_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		4 / 4 ALA A 289
ALA A 292
ALA A 293
ALA A 296
 None
 0.13A 4oadA-3htvA:
undetectable		 4oadA-3htvA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		4 / 4 ALA A 289
ALA A 292
ALA A 293
ALA A 296
 None
 0.10A 4oaeA-3htvA:
undetectable		 4oaeA-3htvA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		4 / 7 GLU A 185
GLY A 144
GLY A 162
ALA A 137
 None
 0.68A 5e26A-3htvA:
4.4
5e26B-3htvA:
5.0		 5e26A-3htvA:
23.04
5e26B-3htvA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		4 / 7 ALA A 137
GLU A 185
GLY A 144
GLY A 162
 None
 0.68A 5e26A-3htvA:
4.0
5e26B-3htvA:
undetectable		 5e26A-3htvA:
23.04
5e26B-3htvA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		4 / 7 GLU A 185
GLY A 144
GLY A 162
ALA A 137
 None
 0.70A 5e26C-3htvA:
6.3
5e26D-3htvA:
3.8		 5e26C-3htvA:
23.04
5e26D-3htvA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		4 / 8 ALA A 137
GLU A 185
GLY A 144
GLY A 162
 None
 0.69A 5e26C-3htvA:
7.0
5e26D-3htvA:
7.0		 5e26C-3htvA:
23.04
5e26D-3htvA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_C_ADNC501_1
(-)		 3htv D-ALLOSE KINASE
(Escherichia
coli) 		5 / 12 LEU A  98
LEU A 106
LEU A  67
MET A  13
PHE A  71
 None
 1.49A 6gbnC-3htvA:
undetectable		 6gbnC-3htvA:
20.95