SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3htx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_C_115C4_2
(HMG-COA REDUCTASE)		 3htx HEN1
(Arabidopsis
thaliana) 		4 / 8 CYH A  53
ASN A  65
LEU A  80
ALA A  81
 None
 0.91A 1hwiD-3htxA:
2.4		 1hwiD-3htxA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 3htx HEN1
(Arabidopsis
thaliana) 		4 / 7 GLN A  45
LEU A  50
SER A  34
SER A  36
 G  B  16 ( 4.3A)
None
None
None
 1.11A 1ig3A-3htxA:
2.5
1ig3B-3htxA:
2.9		 1ig3A-3htxA:
15.66
1ig3B-3htxA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9A_B_BEZB307_0
(CHLOROCATECHOL
1,2-DIOXYGENASE)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 ILE A 360
GLY A 354
TYR A 314
HIS A 399
GLN A 398
 None
 1.18A 1s9aB-3htxA:
undetectable		 1s9aB-3htxA:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3htx HEN1
(Arabidopsis
thaliana) 		3 / 3 PHE A 817
TYR A 924
TYR A 775
 None
 1.03A 1x70B-3htxA:
undetectable		 1x70B-3htxA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 ALA A 312
ILE A 320
ILE A 224
LEU A 255
ILE A 249
 None
 1.05A 1xozA-3htxA:
undetectable		 1xozA-3htxA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 LEU A 732
GLY A 725
SER A 730
ALA A 754
ALA A 752
 None
 1.08A 2br4A-3htxA:
8.2		 2br4A-3htxA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 LEU A 130
VAL A 140
ALA A 129
LEU A 206
TYR A 198
 None
 1.25A 2japA-3htxA:
6.3		 2japA-3htxA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 LEU A 130
VAL A 140
ALA A 129
LEU A 206
TYR A 198
 None
 1.24A 2japB-3htxA:
6.1		 2japB-3htxA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 LEU A 130
VAL A 140
ALA A 129
LEU A 206
TYR A 198
 None
 1.25A 2japC-3htxA:
6.5		 2japC-3htxA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 LEU A 130
VAL A 140
ALA A 129
LEU A 206
TYR A 198
 None
 1.21A 2japD-3htxA:
6.1		 2japD-3htxA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_2
(CYTOCHROME P450 2C8)		 3htx HEN1
(Arabidopsis
thaliana) 		4 / 8 ILE A 611
ILE A 561
VAL A 628
ALA A 637
 None
 0.66A 2nniA-3htxA:
undetectable		 2nniA-3htxA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 GLY A 721
GLY A 723
GLY A 725
ILE A 779
VAL A 797
 SAH  A 951 (-4.3A)
SAH  A 951 (-3.7A)
None
SAH  A 951 (-3.9A)
SAH  A 951 (-3.9A)
 0.63A 2oxtB-3htxA:
8.5		 2oxtB-3htxA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_2
(RENIN)		 3htx HEN1
(Arabidopsis
thaliana) 		4 / 8 SER A 712
SER A 715
THR A 716
LEU A 786
 None
 1.16A 2v0zO-3htxA:
undetectable		 2v0zO-3htxA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 3htx HEN1
(Arabidopsis
thaliana) 		3 / 3 GLY A 723
ASP A 745
SER A 747
 SAH  A 951 (-3.7A)
SAH  A 951 (-2.8A)
U  C   1 (-2.6A)
 0.59A 3brfA-3htxA:
undetectable		 3brfA-3htxA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUF_A_AEGA394_0
(BETA-SECRETASE 1)		 3htx HEN1
(Arabidopsis
thaliana) 		4 / 5 ASP A 776
ILE A 742
ILE A 927
GLY A 777
 None
 0.87A 3bufA-3htxA:
undetectable		 3bufA-3htxA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 ASP A 719
GLY A 721
LEU A 727
ASP A 745
ILE A 746
 None
SAH  A 951 (-4.3A)
None
SAH  A 951 (-2.8A)
SAH  A 951 (-3.8A)
 1.00A 3cjtC-3htxA:
12.7		 3cjtC-3htxA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 9 GLY A 123
GLU A 119
LEU A 122
LEU A 126
ILE A 110
 None
 1.38A 3nbqA-3htxA:
undetectable		 3nbqA-3htxA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 LEU A 671
ALA A 568
LEU A 664
LEU A 665
ILE A 369
 None
 1.19A 3olsB-3htxA:
undetectable		 3olsB-3htxA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 3htx HEN1
(Arabidopsis
thaliana) 		3 / 4 SER A 271
GLY A 317
GLU A 164
 None
 0.53A 3raeA-3htxA:
undetectable
3raeC-3htxA:
2.1		 3raeA-3htxA:
19.75
3raeC-3htxA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 3htx HEN1
(Arabidopsis
thaliana) 		3 / 3 ASN A 382
GLU A 614
ARG A 384
 None
 0.82A 3wxoA-3htxA:
undetectable		 3wxoA-3htxA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 GLY A 721
ILE A 779
LEU A 795
VAL A 797
HIS A 800
 SAH  A 951 (-4.3A)
SAH  A 951 (-3.9A)
SAH  A 951 (-3.9A)
SAH  A 951 (-3.9A)
MG  A 950 ( 3.2A)
 0.79A 4azsA-3htxA:
12.8		 4azsA-3htxA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 ARG A 701
GLY A 721
ILE A 779
LEU A 795
VAL A 797
 G  B  22 (-3.9A)
SAH  A 951 (-4.3A)
SAH  A 951 (-3.9A)
SAH  A 951 (-3.9A)
SAH  A 951 (-3.9A)
 0.85A 4aztA-3htxA:
11.9		 4aztA-3htxA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 GLY A 721
ILE A 779
LEU A 795
VAL A 797
HIS A 800
 SAH  A 951 (-4.3A)
SAH  A 951 (-3.9A)
SAH  A 951 (-3.9A)
SAH  A 951 (-3.9A)
MG  A 950 ( 3.2A)
 0.79A 4azvA-3htxA:
14.6		 4azvA-3htxA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 ILE A 171
LEU A 192
GLY A 191
ASN A 259
ALA A 179
 None
 1.18A 4eb4A-3htxA:
undetectable		 4eb4A-3htxA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 ILE A 171
LEU A 192
GLY A 191
ASN A 259
ALA A 179
 None
 1.20A 4eb4B-3htxA:
undetectable		 4eb4B-3htxA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_A_SAMA301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 ARG A 701
GLY A 721
GLY A 723
SER A 747
VAL A 797
 G  B  22 (-3.9A)
SAH  A 951 (-4.3A)
SAH  A 951 (-3.7A)
U  C   1 (-2.6A)
SAH  A 951 (-3.9A)
 0.49A 4htfA-3htxA:
16.0		 4htfA-3htxA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HTF_B_SAMB301_0
(S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 ARG A 701
GLY A 721
GLY A 723
SER A 747
VAL A 797
 G  B  22 (-3.9A)
SAH  A 951 (-4.3A)
SAH  A 951 (-3.7A)
U  C   1 (-2.6A)
SAH  A 951 (-3.9A)
 0.52A 4htfB-3htxA:
15.5		 4htfB-3htxA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 3htx HEN1
(Arabidopsis
thaliana) 		3 / 4 SER A 271
GLY A 317
GLU A 164
 None
 0.52A 4juoA-3htxA:
undetectable
4juoC-3htxA:
2.6		 4juoA-3htxA:
19.75
4juoC-3htxA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_2
(ADENOSINE KINASE)		 3htx HEN1
(Arabidopsis
thaliana) 		4 / 5 SER A 486
LEU A 387
LEU A 373
ASN A 479
 None
None
None
U  B   9 ( 4.2A)
 1.20A 4n09B-3htxA:
4.2		 4n09B-3htxA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3htx HEN1
(Arabidopsis
thaliana) 		4 / 7 PHE A 809
ILE A 779
TYR A 924
PHE A 817
 None
SAH  A 951 (-3.9A)
None
None
 1.29A 4o7gA-3htxA:
undetectable
4o7gB-3htxA:
undetectable		 4o7gA-3htxA:
13.37
4o7gB-3htxA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 3htx HEN1
(Arabidopsis
thaliana) 		4 / 6 PHE A 809
ILE A 779
TYR A 924
PHE A 817
 None
SAH  A 951 (-3.9A)
None
None
 1.30A 4o7gB-3htxA:
undetectable		 4o7gB-3htxA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 3htx HEN1
(Arabidopsis
thaliana) 		7 / 12 GLY A 721
GLY A 723
ILE A 746
SER A 747
LEU A 795
VAL A 797
HIS A 800
 SAH  A 951 (-4.3A)
SAH  A 951 (-3.7A)
SAH  A 951 (-3.8A)
U  C   1 (-2.6A)
SAH  A 951 (-3.9A)
SAH  A 951 (-3.9A)
MG  A 950 ( 3.2A)
 0.58A 4qdjA-3htxA:
16.4		 4qdjA-3htxA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 3htx HEN1
(Arabidopsis
thaliana) 		7 / 12 GLY A 721
GLY A 723
SER A 726
ILE A 746
SER A 747
VAL A 797
HIS A 800
 SAH  A 951 (-4.3A)
SAH  A 951 (-3.7A)
SAH  A 951 (-3.1A)
SAH  A 951 (-3.8A)
U  C   1 (-2.6A)
SAH  A 951 (-3.9A)
MG  A 950 ( 3.2A)
 0.66A 4qdjA-3htxA:
16.4		 4qdjA-3htxA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 GLY A 723
SER A 726
ILE A 746
SER A 778
GLN A 805
 SAH  A 951 (-3.7A)
SAH  A 951 (-3.1A)
SAH  A 951 (-3.8A)
SAH  A 951 (-3.2A)
None
 0.90A 4rtpA-3htxA:
11.1		 4rtpA-3htxA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTP_A_SAMA301_0
(DNA ADENINE
METHYLASE)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 GLY A 723
SER A 726
ILE A 746
TYR A 924
ASP A 719
 SAH  A 951 (-3.7A)
SAH  A 951 (-3.1A)
SAH  A 951 (-3.8A)
None
None
 1.21A 4rtpA-3htxA:
11.1		 4rtpA-3htxA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 ARG A 701
GLY A 721
ILE A 779
LEU A 795
VAL A 797
 G  B  22 (-3.9A)
SAH  A 951 (-4.3A)
SAH  A 951 (-3.9A)
SAH  A 951 (-3.9A)
SAH  A 951 (-3.9A)
 0.75A 4uw0A-3htxA:
12.1		 4uw0A-3htxA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 11 SER A 726
GLY A 725
ASP A 719
GLU A 796
THR A 793
 SAH  A 951 (-3.1A)
None
None
MG  A 950 ( 3.0A)
None
 1.28A 4xt7A-3htxA:
2.1		 4xt7A-3htxA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 SER A 726
GLY A 725
ASP A 719
GLU A 796
THR A 793
 SAH  A 951 (-3.1A)
None
None
MG  A 950 ( 3.0A)
None
 1.29A 4xt8A-3htxA:
undetectable		 4xt8A-3htxA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 GLY A 721
ASP A 745
SER A 778
ILE A 779
VAL A 797
 SAH  A 951 (-4.3A)
SAH  A 951 (-2.8A)
SAH  A 951 (-3.2A)
SAH  A 951 (-3.9A)
SAH  A 951 (-3.9A)
 0.92A 5dpdB-3htxA:
13.7		 5dpdB-3htxA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 ASP A 247
HIS A 244
PRO A 141
HIS A 120
ASP A 149
 None
 1.47A 5ef8A-3htxA:
2.9		 5ef8A-3htxA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3htx HEN1
(Arabidopsis
thaliana) 		4 / 7 CYH A 807
ILE A 798
LEU A 876
ALA A 873
 None
 1.01A 5hrqE-3htxA:
undetectable
5hrqF-3htxA:
undetectable
5hrqJ-3htxA:
undetectable		 5hrqE-3htxA:
2.19
5hrqF-3htxA:
3.25
5hrqJ-3htxA:
3.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 3htx HEN1
(Arabidopsis
thaliana) 		4 / 6 ILE A 561
VAL A 615
VAL A 559
SER A 619
 None
 0.91A 5jwaH-3htxA:
2.9		 5jwaH-3htxA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 10 ILE A 152
ILE A 145
LEU A 192
ILE A 159
ASN A 160
 None
 1.27A 5vkqA-3htxA:
undetectable
5vkqD-3htxA:
undetectable		 5vkqA-3htxA:
19.86
5vkqD-3htxA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 10 ILE A 159
ASN A 160
ILE A 152
ILE A 145
LEU A 192
 None
 1.25A 5vkqA-3htxA:
undetectable
5vkqB-3htxA:
undetectable		 5vkqA-3htxA:
19.86
5vkqB-3htxA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 10 ILE A 159
ASN A 160
ILE A 152
ILE A 145
LEU A 192
 None
 1.26A 5vkqC-3htxA:
undetectable
5vkqD-3htxA:
undetectable		 5vkqC-3htxA:
19.86
5vkqD-3htxA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WY0_A_SAMA800_0
(SMALL RNA
2'-O-METHYLTRANSFERA
SE)		 3htx HEN1
(Arabidopsis
thaliana) 		6 / 12 GLY A 721
GLY A 723
ASP A 745
ILE A 746
SER A 778
HIS A 800
 SAH  A 951 (-4.3A)
SAH  A 951 (-3.7A)
SAH  A 951 (-2.8A)
SAH  A 951 (-3.8A)
SAH  A 951 (-3.2A)
MG  A 950 ( 3.2A)
 0.58A 5wy0A-3htxA:
26.5		 5wy0A-3htxA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3htx HEN1
(Arabidopsis
thaliana) 		6 / 12 ASP A 336
ASP A 247
LEU A 246
PRO A 121
GLY A 123
LEU A 122
 None
 1.35A 6b0iB-3htxA:
undetectable		 6b0iB-3htxA:
6.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 9 SER A 347
SER A 274
GLY A 268
ALA A 327
SER A 328
 None
 1.07A 6bklE-3htxA:
undetectable
6bklF-3htxA:
undetectable
6bklG-3htxA:
undetectable
6bklH-3htxA:
undetectable		 6bklE-3htxA:
2.67
6bklF-3htxA:
2.67
6bklG-3htxA:
2.67
6bklH-3htxA:
2.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 3htx HEN1
(Arabidopsis
thaliana) 		5 / 12 ILE A 351
PHE A 267
GLY A 317
ILE A 224
LEU A 278
 None
 1.14A 6dwnC-3htxA:
undetectable		 6dwnC-3htxA:
5.37