SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hur'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		5 / 10 ARG A  26
THR A  57
ALA A  60
ALA A  36
ILE A 228
 None
 1.23A 1gtnB-3hurA:
undetectable
1gtnC-3hurA:
undetectable		 1gtnB-3hurA:
11.51
1gtnC-3hurA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		5 / 10 LEU A 377
LEU A  15
ILE A 381
ILE A  64
LEU A  50
 None
 1.21A 1wopA-3hurA:
1.4		 1wopA-3hurA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 5 ILE A 337
SER A 254
ARG A 333
LEU A 336
 None
 1.18A 1y0xX-3hurA:
undetectable		 1y0xX-3hurA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 7 GLN A  55
ARG A  26
LEU A  81
ASP A  61
 None
 0.99A 2qqcB-3hurA:
undetectable
2qqcC-3hurA:
undetectable		 2qqcB-3hurA:
15.14
2qqcC-3hurA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 7 LEU A  81
ASP A  61
GLN A  55
ARG A  26
 None
 0.98A 2qqcA-3hurA:
undetectable
2qqcF-3hurA:
undetectable		 2qqcA-3hurA:
10.83
2qqcF-3hurA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 7 LEU A  81
ASP A  61
GLN A  55
ARG A  26
 None
 1.07A 2qqcG-3hurA:
undetectable
2qqcJ-3hurA:
undetectable		 2qqcG-3hurA:
10.83
2qqcJ-3hurA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 7 LEU A  81
ASP A  61
GLN A  55
ARG A  26
 None
 1.00A 2qqcI-3hurA:
undetectable
2qqcL-3hurA:
undetectable		 2qqcI-3hurA:
10.83
2qqcL-3hurA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 8 GLN A 226
SER A 229
GLY A  44
GLY A  46
 SO4  A 395 (-4.6A)
None
None
None
 0.76A 2vinA-3hurA:
undetectable		 2vinA-3hurA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		5 / 12 ILE A 143
SER A 144
LYS A 147
LEU A 158
ILE A 106
 None
 1.09A 3cd2A-3hurA:
undetectable		 3cd2A-3hurA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 8 THR A 133
GLN A 182
ALA A 166
HIS A 164
 None
 1.03A 3kp6A-3hurA:
undetectable		 3kp6A-3hurA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		6 / 12 GLY A  87
ALA A  88
ASP A  93
ILE A  64
VAL A 124
ILE A 104
 None
 1.43A 3lzuB-3hurA:
undetectable		 3lzuB-3hurA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 4 LEU A  45
GLY A  42
GLY A  44
THR A 346
 None
 0.88A 3si7A-3hurA:
undetectable		 3si7A-3hurA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 7 GLY A 172
ALA A 171
ALA A 168
ASP A 169
 None
 0.86A 3ur0B-3hurA:
undetectable		 3ur0B-3hurA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 8 VAL A 252
ARG A 371
ILE A 369
GLU A 343
 None
 1.11A 4a97C-3hurA:
undetectable		 4a97C-3hurA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AN2_A_EUIA1382_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 4 ASN A 204
SER A  59
LEU A  22
THR A 207
 SO4  A 395 (-4.0A)
None
None
None
 1.38A 4an2A-3hurA:
undetectable		 4an2A-3hurA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_D_NCTD501_1
(CYTOCHROME P450 2A6)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 7 PHE A  54
GLY A  42
ILE A 249
LEU A  15
 None
 0.71A 4ejjD-3hurA:
undetectable		 4ejjD-3hurA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 7 MET A 297
VAL A 252
TRP A 293
PHE A 287
 None
 1.48A 4jseA-3hurA:
undetectable
4jseB-3hurA:
undetectable		 4jseA-3hurA:
24.21
4jseB-3hurA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBS_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		5 / 12 LEU A 365
ALA A 366
ILE A 311
ARG A 296
LEU A 285
 None
SO4  A 396 ( 4.5A)
None
None
None
 1.05A 5hbsA-3hurA:
undetectable		 5hbsA-3hurA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		3 / 3 ALA A  18
ASN A  21
LEU A  22
 None
 0.40A 5i1nB-3hurA:
undetectable		 5i1nB-3hurA:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		3 / 3 ALA A  18
ASN A  21
LEU A  22
 None
 0.43A 5i1oA-3hurA:
undetectable		 5i1oA-3hurA:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 7 SER A  59
ALA A  53
ILE A  48
LEU A  79
 None
 0.96A 5te8A-3hurA:
undetectable		 5te8A-3hurA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		4 / 6 MET A 297
GLY A 292
TRP A 293
LEU A 365
 None
SO4  A 396 (-3.4A)
None
None
 1.04A 6fosA-3hurA:
undetectable		 6fosA-3hurA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 3hur ALANINE RACEMASE
(Oenococcus
oeni) 		3 / 3 ASP A 141
ASP A 129
ASN A 352
 None
 0.71A 6gngB-3hurA:
undetectable		 6gngB-3hurA:
21.27