SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hv2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XN3_A_ID8A1356_1 (THYROXINE-BINDING GLOBULIN)	3hv2	RESPONSE REGULATOR/HD DOMAIN PROTEIN (Pseudomonas protegens)	4 / 8	LEU A 90 LEU A 31 LEU A 17 ARG A 27	None	1.20A	2xn3A-3hv2A: undetectable 2xn3B-3hv2A: undetectable	2xn3A-3hv2A: 21.27 2xn3B-3hv2A: 12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MBS_B_MRVB1101_2 (CHIMERA PROTEIN OF C-C CHEMOKINE RECEPTOR TYPE 5 AND RUBREDOXIN)	3hv2	RESPONSE REGULATOR/HD DOMAIN PROTEIN (Pseudomonas protegens)	4 / 5	TYR A 37 THR A 91 LEU A 89 THR A 86	None SO4 A 152 (-3.4A) None None	1.46A	4mbsB-3hv2A: undetectable	4mbsB-3hv2A: 16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MVM_B_PFLB510_1 (PROTON-GATED ION CHANNEL)	3hv2	RESPONSE REGULATOR/HD DOMAIN PROTEIN (Pseudomonas protegens)	4 / 6	ILE A 24 ALA A 63 LEU A 90 ILE A 61	None SO4 A 152 (-3.2A) None None	0.77A	5mvmB-3hv2A: undetectable 5mvmC-3hv2A: undetectable	5mvmB-3hv2A: 16.11 5mvmC-3hv2A: 16.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2XN3_A_ID8A1356_1","THYROXINE-BINDING GLOBULIN;THYROXINE-BINDING GLOBULIN","3hv2","RESPONSE REGULATOR\/HD DOMAIN PROTEIN","Pseudomonas protegens",4,"LEU A  90;LEU A  31;LEU A  17;ARG A  27","None","1.20A","2xn3A-3hv2A:undetectable;2xn3B-3hv2A:undetectable","2xn3A-3hv2A:21.27;2xn3B-3hv2A:12.70"],["4MBS_B_MRVB1101_2","CHIMERA PROTEIN OF C-C CHEMOKINE RECEPTOR TYPE 5 AND RUBREDOXIN","3hv2","RESPONSE REGULATOR\/HD DOMAIN PROTEIN","Pseudomonas protegens",4,"TYR A  37;THR A  91;LEU A  89;THR A  86","None;SO4 A 152 (-3.4A);None;None","1.46A","4mbsB-3hv2A:undetectable","4mbsB-3hv2A:16.59"],["5MVM_B_PFLB510_1","PROTON-GATED ION CHANNEL;PROTON-GATED ION CHANNEL","3hv2","RESPONSE REGULATOR\/HD DOMAIN PROTEIN","Pseudomonas protegens",4,"ILE A  24;ALA A  63;LEU A  90;ILE A  61","None;SO4 A 152 (-3.2A);None;None","0.77A","5mvmB-3hv2A:undetectable;5mvmC-3hv2A:undetectable","5mvmB-3hv2A:16.11;5mvmC-3hv2A:16.11"]]