SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 539
GLN A 577
SER A 595
ILE A 594
LEU A 610
 None
None
GOL  A 903 (-2.5A)
None
None
 1.15A 3ia4A-3hv9A:
undetectable		 3ia4A-3hv9A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_C_MTXC164_1
(DIHYDROFOLATE
REDUCTASE)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		5 / 12 LEU A 539
GLN A 577
SER A 595
ILE A 594
LEU A 610
 None
None
GOL  A 903 (-2.5A)
None
None
 1.11A 3ia4C-3hv9A:
undetectable		 3ia4C-3hv9A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		5 / 11 ARG A 457
LEU A 480
LEU A 451
LEU A 481
LEU A 447
 GOL  A 906 ( 4.5A)
None
None
None
None
 1.03A 4or0A-3hv9A:
undetectable		 4or0A-3hv9A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_B_NPSB603_1
(SERUM ALBUMIN)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		5 / 11 ARG A 457
LEU A 480
LEU A 451
LEU A 481
LEU A 447
 GOL  A 906 ( 4.5A)
None
None
None
None
 1.12A 4or0B-3hv9A:
undetectable		 4or0B-3hv9A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 531
PRO A 462
VAL A 463
PHE A 686
 None
 0.84A 4w5oA-3hv9A:
undetectable		 4w5oA-3hv9A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 531
PRO A 462
VAL A 463
PHE A 686
 None
 0.85A 4z4cA-3hv9A:
undetectable		 4z4cA-3hv9A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 531
PRO A 462
VAL A 463
PHE A 686
 None
 0.86A 4z4dA-3hv9A:
undetectable		 4z4dA-3hv9A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 531
PRO A 462
VAL A 463
PHE A 686
 None
 0.87A 4z4eA-3hv9A:
undetectable		 4z4eA-3hv9A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		5 / 10 ILE A 515
ILE A 511
VAL A 532
PHE A 564
ALA A 592
 None
 1.10A 5nukA-3hv9A:
undetectable		 5nukA-3hv9A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA602_0
(THIOCYANATE
DEHYDROGENASE)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 524
HIS A 521
HIS A 526
 None
 0.96A 5oexA-3hv9A:
undetectable		 5oexA-3hv9A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB602_0
(THIOCYANATE
DEHYDROGENASE)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 524
HIS A 521
HIS A 526
 None
 1.03A 5oexB-3hv9A:
undetectable		 5oexB-3hv9A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC603_0
(THIOCYANATE
DEHYDROGENASE)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 524
HIS A 521
HIS A 526
 None
 0.99A 5oexC-3hv9A:
undetectable		 5oexC-3hv9A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD603_0
(THIOCYANATE
DEHYDROGENASE)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 524
HIS A 521
HIS A 526
 None
 0.94A 5oexD-3hv9A:
undetectable		 5oexD-3hv9A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		4 / 6 PHE A 531
PRO A 462
VAL A 463
PHE A 686
 None
 0.83A 5t7bA-3hv9A:
undetectable		 5t7bA-3hv9A:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		4 / 4 LEU A 562
LEU A 557
SER A 514
ALA A 519
 None
 1.10A 5uunA-3hv9A:
undetectable		 5uunA-3hv9A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXD_B_ZITB501_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E MPHH)		 3hv9 PROTEIN FIMX
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 511
LEU A 458
VAL A 476
ALA A 497
GLY A 501
 None
GOL  A 906 (-4.0A)
None
None
None
 1.08A 5uxdB-3hv9A:
undetectable		 5uxdB-3hv9A:
22.71