SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hve'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.64A 1fbyA-3hveA:
undetectable		 1fbyA-3hveA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.70A 1fbyA-3hveB:
undetectable		 1fbyA-3hveB:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.64A 1fbyB-3hveA:
undetectable		 1fbyB-3hveA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.69A 1fbyB-3hveB:
undetectable		 1fbyB-3hveB:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.65A 1fm6A-3hveA:
undetectable		 1fm6A-3hveA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.72A 1fm6A-3hveA:
undetectable		 1fm6A-3hveA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		6 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
LEU B  87
 None
 0.88A 1fm6A-3hveB:
undetectable		 1fm6A-3hveB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ALA B  50
ALA B  51
LEU A  20
ALA A  19
LEU B  87
 None
 0.93A 1fm9A-3hveB:
undetectable		 1fm9A-3hveB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.66A 1fm9A-3hveA:
undetectable		 1fm9A-3hveA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.73A 1fm9A-3hveA:
undetectable		 1fm9A-3hveA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
LEU B  87
 None
 0.80A 1fm9A-3hveB:
undetectable		 1fm9A-3hveB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.66A 1k74A-3hveA:
undetectable		 1k74A-3hveA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.73A 1k74A-3hveA:
undetectable		 1k74A-3hveA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		6 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
LEU B  87
 None
 0.90A 1k74A-3hveB:
undetectable		 1k74A-3hveB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 LEU A  48
SER A  52
LEU A 114
LYS A 118
ILE A  73
 None
 1.35A 1lbcA-3hveA:
undetectable
1lbcC-3hveA:
undetectable		 1lbcA-3hveA:
22.11
1lbcC-3hveA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_C_CYZC331_1
(GLUTAMINE RECEPTOR 2)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  73
LEU A  48
SER A  52
LEU A 114
LYS A 118
 None
 1.48A 1lbcA-3hveA:
undetectable
1lbcC-3hveA:
undetectable		 1lbcA-3hveA:
22.11
1lbcC-3hveA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3hve GIGAXONIN
(Homo
sapiens) 		4 / 8 ILE A  55
LEU A  48
THR A 115
LEU A 114
 None
 0.91A 1v55N-3hveA:
2.5
1v55W-3hveA:
undetectable		 1v55N-3hveA:
17.61
1v55W-3hveA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.69A 1xdkA-3hveA:
undetectable		 1xdkA-3hveA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
LEU A  20
ALA A  19
LEU B  87
 None
 0.91A 1xdkA-3hveB:
undetectable		 1xdkA-3hveB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.64A 1xdkE-3hveA:
undetectable		 1xdkE-3hveA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.69A 1xdkE-3hveA:
undetectable		 1xdkE-3hveA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.72A 1xdkE-3hveB:
undetectable		 1xdkE-3hveB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
LEU A  20
ALA A  19
LEU B  87
 None
 0.91A 1xdkE-3hveB:
undetectable		 1xdkE-3hveB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.68A 1xiuA-3hveA:
undetectable		 1xiuA-3hveA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.79A 1xiuA-3hveA:
undetectable		 1xiuA-3hveA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.73A 1xiuA-3hveB:
undetectable		 1xiuA-3hveB:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
LEU A  20
ALA A  19
LEU B  87
 None
 0.95A 1xiuA-3hveB:
undetectable		 1xiuA-3hveB:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.67A 1xlsA-3hveA:
undetectable		 1xlsA-3hveA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.79A 1xlsA-3hveA:
undetectable		 1xlsA-3hveA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.72A 1xlsA-3hveB:
undetectable		 1xlsA-3hveB:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.69A 1xlsB-3hveA:
undetectable		 1xlsB-3hveA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.80A 1xlsB-3hveA:
undetectable		 1xlsB-3hveA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.73A 1xlsB-3hveB:
undetectable		 1xlsB-3hveB:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.69A 1xlsC-3hveA:
undetectable		 1xlsC-3hveA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.80A 1xlsC-3hveA:
undetectable		 1xlsC-3hveA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.73A 1xlsC-3hveB:
undetectable		 1xlsC-3hveB:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.68A 1xlsD-3hveA:
undetectable		 1xlsD-3hveA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.80A 1xlsD-3hveA:
undetectable		 1xlsD-3hveA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.73A 1xlsD-3hveB:
undetectable		 1xlsD-3hveB:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  90
ALA A  51
LEU A 112
LEU A  34
ILE A  73
 None
 1.07A 1xzxX-3hveA:
undetectable		 1xzxX-3hveA:
24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.62A 2aclG-3hveA:
undetectable		 2aclG-3hveA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.73A 2aclG-3hveB:
undetectable		 2aclG-3hveB:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 3hve GIGAXONIN
(Homo
sapiens) 		4 / 6 ARG A  84
GLU A  39
ILE A  41
PRO A  42
 None
 0.98A 2fcnA-3hveA:
undetectable
2fcnB-3hveA:
undetectable		 2fcnA-3hveA:
15.19
2fcnB-3hveA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  90
ALA A  51
LEU A 112
LEU A  34
ILE A  73
 None
 1.08A 2h77A-3hveA:
undetectable		 2h77A-3hveA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H79_A_T3A1_1
(THRA PROTEIN)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  90
ALA A  51
LEU A 112
LEU A  34
ILE A  73
 None
 1.07A 2h79A-3hveA:
undetectable		 2h79A-3hveA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 11 ILE A  55
ALA A  51
LEU A  87
ILE A  78
LEU A  36
 None
 1.34A 2zzaB-3hveA:
undetectable		 2zzaB-3hveA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hve GIGAXONIN
(Homo
sapiens) 		4 / 7 ILE A  55
LEU A  48
THR A 115
LEU A 114
 None
 0.94A 3ag3A-3hveA:
2.8
3ag3J-3hveA:
undetectable		 3ag3A-3hveA:
17.61
3ag3J-3hveA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  95
LEU B  16
LYS A 118
PRO A  53
ILE A  86
 None
 1.11A 3cd2A-3hveA:
undetectable		 3cd2A-3hveA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.78A 3dzyA-3hveA:
undetectable		 3dzyA-3hveA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
LEU A  20
ALA A  19
LEU B  87
 None
 0.94A 3dzyA-3hveB:
undetectable		 3dzyA-3hveB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 10 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.59A 3falC-3hveA:
undetectable		 3falC-3hveA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 10 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.66A 3falC-3hveB:
undetectable		 3falC-3hveB:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 11 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.54A 3fc6A-3hveA:
undetectable		 3fc6A-3hveA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 11 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.67A 3fc6A-3hveB:
undetectable		 3fc6A-3hveB:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWS_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  90
ALA A  51
LEU A 112
LEU A  34
ILE A  73
 None
 1.05A 3gwsX-3hveA:
undetectable		 3gwsX-3hveA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.68A 3oapA-3hveA:
undetectable		 3oapA-3hveA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.80A 3oapA-3hveA:
undetectable		 3oapA-3hveA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.54A 4k6iA-3hveA:
undetectable		 4k6iA-3hveA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  90
ALA A  51
LEU A 112
LEU A  34
ILE A  73
 None
 1.05A 4lnwA-3hveA:
undetectable		 4lnwA-3hveA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  90
ALA A  51
LEU A 112
LEU A  34
ILE A  73
 None
 1.08A 4lnxA-3hveA:
undetectable		 4lnxA-3hveA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.78A 4nqaH-3hveA:
undetectable		 4nqaH-3hveA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 3hve GIGAXONIN
(Homo
sapiens) 		4 / 6 LEU B  75
ILE B  78
LEU B 112
TYR B  54
 None
 0.96A 4w5nA-3hveB:
undetectable		 4w5nA-3hveB:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 HIS A 150
VAL A 181
LEU A 157
THR A 154
ALA A 153
 None
 1.33A 4yhaG-3hveA:
undetectable		 4yhaG-3hveA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hve GIGAXONIN
(Homo
sapiens) 		4 / 7 ILE A  55
LEU A  48
THR A 115
LEU A 114
 None
 0.95A 5b1aA-3hveA:
2.5
5b1aJ-3hveA:
undetectable		 5b1aA-3hveA:
17.61
5b1aJ-3hveA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hve GIGAXONIN
(Homo
sapiens) 		4 / 7 ILE A  55
LEU A  48
THR A 115
LEU A 114
 None
 0.97A 5b3sA-3hveA:
2.5
5b3sJ-3hveA:
undetectable		 5b3sA-3hveA:
17.61
5b3sJ-3hveA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.62A 5uanA-3hveA:
undetectable		 5uanA-3hveA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.66A 5uanA-3hveA:
undetectable		 5uanA-3hveA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.68A 5uanA-3hveB:
undetectable		 5uanA-3hveB:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
LEU A  20
ALA A  19
LEU B  87
 None
 0.87A 5uanA-3hveB:
undetectable		 5uanA-3hveB:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 3hve GIGAXONIN
(Homo
sapiens) 		4 / 8 LEU A 178
VAL A 181
LEU A 171
ILE A 135
 None
 0.92A 5v0vA-3hveA:
undetectable		 5v0vA-3hveA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hve GIGAXONIN
(Homo
sapiens) 		4 / 7 ILE A  55
LEU A  48
THR A 115
LEU A 114
 None
 0.92A 5xdqN-3hveA:
undetectable
5xdqW-3hveA:
undetectable		 5xdqN-3hveA:
17.61
5xdqW-3hveA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3hve GIGAXONIN
(Homo
sapiens) 		4 / 7 ILE A  55
LEU A  48
THR A 115
LEU A 114
 None
 0.93A 5xdxA-3hveA:
undetectable
5xdxJ-3hveA:
undetectable		 5xdxA-3hveA:
17.61
5xdxJ-3hveA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.68A 5z12B-3hveA:
undetectable		 5z12B-3hveA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.75A 5z12B-3hveA:
undetectable		 5z12B-3hveA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.71A 5z12B-3hveB:
undetectable		 5z12B-3hveB:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
LEU A  20
ALA A  19
LEU B  87
 None
 0.93A 5z12B-3hveB:
undetectable		 5z12B-3hveB:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.80A 5z12C-3hveA:
undetectable		 5z12C-3hveA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.76A 5z12C-3hveB:
undetectable		 5z12C-3hveB:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
LEU A  20
ALA A  19
LEU B  87
 None
 0.97A 5z12C-3hveB:
undetectable		 5z12C-3hveB:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hve GIGAXONIN
(Homo
sapiens) 		4 / 6 GLN B 107
PHE B 140
LEU B 125
PHE B 124
 None
 1.10A 5z84P-3hveB:
undetectable
5z84W-3hveB:
undetectable		 5z84P-3hveB:
16.30
5z84W-3hveB:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hve GIGAXONIN
(Homo
sapiens) 		4 / 7 ILE A  55
LEU A  48
THR A 115
LEU A 114
 None
 0.96A 5zcpA-3hveA:
undetectable
5zcpJ-3hveA:
undetectable		 5zcpA-3hveA:
17.61
5zcpJ-3hveA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hve GIGAXONIN
(Homo
sapiens) 		4 / 7 ILE A  55
LEU A  48
THR A 115
LEU A 114
 None
 0.96A 5zcqA-3hveA:
2.5
5zcqJ-3hveA:
undetectable		 5zcqA-3hveA:
17.61
5zcqJ-3hveA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
GIGAXONIN
(Homo
sapiens;
Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.70A 6a5yD-3hveA:
undetectable		 6a5yD-3hveA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
GIGAXONIN
(Homo
sapiens;
Homo
sapiens) 		6 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
LEU B  87
 None
 0.91A 6a5yD-3hveB:
undetectable		 6a5yD-3hveB:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
GIGAXONIN
(Homo
sapiens;
Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.73A 6a5zD-3hveA:
undetectable		 6a5zD-3hveA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
GIGAXONIN
(Homo
sapiens;
Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
ALA A  51
LEU B  20
ALA B  19
 None
 0.73A 6a5zL-3hveA:
undetectable		 6a5zL-3hveA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
GIGAXONIN
(Homo
sapiens;
Homo
sapiens) 		5 / 12 ILE A  47
ALA A  50
LEU B  20
ALA B  19
LEU A  87
 None
 0.73A 6a5zL-3hveA:
undetectable		 6a5zL-3hveA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
GIGAXONIN
(Homo
sapiens;
Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
ALA B  51
LEU A  20
ALA A  19
 None
 0.77A 6a5zL-3hveB:
undetectable		 6a5zL-3hveB:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hve GIGAXONIN
GIGAXONIN
(Homo
sapiens;
Homo
sapiens) 		5 / 12 ILE B  47
ALA B  50
LEU A  20
ALA A  19
LEU B  87
 None
 0.90A 6a5zL-3hveB:
undetectable		 6a5zL-3hveB:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 10 LEU A  48
SER A  52
LEU A 114
LYS A 118
ILE A  73
 None
 1.44A 6dlzB-3hveA:
undetectable
6dlzC-3hveA:
undetectable		 6dlzB-3hveA:
12.80
6dlzC-3hveA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 11 ILE A  73
LEU A  48
SER A  52
LEU A 114
LYS A 118
 None
 1.44A 6dlzA-3hveA:
undetectable
6dlzD-3hveA:
undetectable		 6dlzA-3hveA:
12.80
6dlzD-3hveA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 10 LEU A  48
SER A  52
LEU A 114
LYS A 118
ILE A  73
 None
 1.43A 6dm1B-3hveA:
undetectable
6dm1C-3hveA:
undetectable		 6dm1B-3hveA:
12.80
6dm1C-3hveA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 11 ILE A  73
LEU A  48
SER A  52
LEU A 114
LYS A 118
 None
 1.44A 6dm1A-3hveA:
undetectable
6dm1D-3hveA:
undetectable		 6dm1A-3hveA:
12.80
6dm1D-3hveA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 10 LEU A  48
SER A  52
LEU A 114
LYS A 118
ILE A  73
 None
 1.44A 6dm2B-3hveA:
undetectable
6dm2C-3hveA:
undetectable		 6dm2B-3hveA:
12.80
6dm2C-3hveA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 10 ILE A  73
LEU A  48
SER A  52
LEU A 114
LYS A 118
 None
 1.44A 6dm2A-3hveA:
undetectable
6dm2D-3hveA:
undetectable		 6dm2A-3hveA:
12.80
6dm2D-3hveA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_1
(-)		 3hve GIGAXONIN
(Homo
sapiens) 		5 / 12 LEU B  97
GLU B  85
ASP B  88
LEU B 117
GLY B  93
 None
 1.47A 6gbnB-3hveB:
undetectable		 6gbnB-3hveB:
18.96