SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hw2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)		 3hw2 PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY M MEMBER 2
(Homo
sapiens) 		4 / 5 LEU B 818
LEU B 852
MET B 822
TRP B 865
 None
 1.41A 4do3A-3hw2B:
undetectable		 4do3A-3hw2B:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3hw2 PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY M MEMBER 2
(Homo
sapiens) 		4 / 4 LEU B 800
LEU B 852
GLN B 867
GLU B 861
 None
 1.09A 4i41A-3hw2B:
undetectable		 4i41A-3hw2B:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_E_ACTE504_0
(RNA POLYMERASE
3D-POL)		 3hw2 PLECKSTRIN HOMOLOGY
DOMAIN-CONTAINING
FAMILY M MEMBER 2
(Homo
sapiens) 		3 / 3 VAL B 798
GLY B 777
LYS B 775
 None
 0.73A 4k50E-3hw2B:
undetectable		 4k50E-3hw2B:
11.94