SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hwc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_B_ZMRB466_2
(NEURAMINIDASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		3 / 3 ASP A3363
ARG A3366
ILE A3292
 None
 0.90A 1a4gB-3hwcA:
undetectable		 1a4gB-3hwcA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_A_MTXA1278_1
(PTERIDINE REDUCTASE
2)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		5 / 10 ARG A3143
SER A3067
ASP A3103
TYR A3085
THR A3350
 None
 1.43A 1mxfA-3hwcA:
undetectable		 1mxfA-3hwcA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_B_MTXB2278_1
(PTERIDINE REDUCTASE
2)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		5 / 11 ARG A3143
SER A3067
ASP A3103
TYR A3085
THR A3350
 None
 1.48A 1mxfB-3hwcA:
undetectable		 1mxfB-3hwcA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_C_MTXC3278_1
(PTERIDINE REDUCTASE
2)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		5 / 11 ARG A3143
SER A3067
ASP A3103
TYR A3085
THR A3350
 None
 1.46A 1mxfC-3hwcA:
undetectable		 1mxfC-3hwcA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_D_MTXD4278_1
(PTERIDINE REDUCTASE
2)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		5 / 11 ARG A3143
SER A3067
ASP A3103
TYR A3085
THR A3350
 None
 1.44A 1mxfD-3hwcA:
undetectable		 1mxfD-3hwcA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 7 MET A3377
GLN A3373
ARG A3438
GLU A3443
 None
 1.33A 1t9wA-3hwcA:
2.5		 1t9wA-3hwcA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_A_ACTA4901_0
(PYRANOSE OXIDASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 6 GLN A3069
PHE A3043
HIS A3105
ASN A3106
 None
 1.40A 1tt0A-3hwcA:
undetectable		 1tt0A-3hwcA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_B_ACTB3901_0
(PYRANOSE OXIDASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 6 GLN A3069
PHE A3043
HIS A3105
ASN A3106
 None
 1.40A 1tt0B-3hwcA:
undetectable		 1tt0B-3hwcA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_C_ACTC6901_0
(PYRANOSE OXIDASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 6 GLN A3069
PHE A3043
HIS A3105
ASN A3106
 None
 1.40A 1tt0C-3hwcA:
undetectable		 1tt0C-3hwcA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT0_D_ACTD5901_0
(PYRANOSE OXIDASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 6 GLN A3069
PHE A3043
HIS A3105
ASN A3106
 None
 1.39A 1tt0D-3hwcA:
undetectable		 1tt0D-3hwcA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 6 ASP A3114
THR A3110
TYR A3112
HIS A3291
 None
 1.37A 2eimN-3hwcA:
0.7
2eimP-3hwcA:
undetectable		 2eimN-3hwcA:
21.31
2eimP-3hwcA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3060
SER A3067
PHE A3058
ASP A3072
 None
 1.11A 2obvA-3hwcA:
undetectable		 2obvA-3hwcA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3060
SER A3067
PHE A3058
ASP A3072
 None
 1.04A 2p02A-3hwcA:
undetectable		 2p02A-3hwcA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM8_A_ACAA511_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ALA A3307
ILE A3303
ILE A3427
TYR A3431
 None
 0.80A 2zm8A-3hwcA:
undetectable		 2zm8A-3hwcA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMA_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ALA A3307
ILE A3303
ILE A3427
TYR A3431
 None
 0.79A 2zmaA-3hwcA:
undetectable		 2zmaA-3hwcA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		3 / 3 TYR A3036
ASP A3253
HIS A3105
 None
 0.81A 3e23A-3hwcA:
undetectable		 3e23A-3hwcA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ILE A3263
PRO A3264
VAL A3227
GLY A3226
 None
 0.69A 3em0B-3hwcA:
undetectable		 3em0B-3hwcA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		3 / 3 ILE A3220
PHE A3258
HIS A3201
 None
 0.68A 3h0aA-3hwcA:
undetectable		 3h0aA-3hwcA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_B_CHDB924_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 7 ARG A3068
PRO A3357
SER A3343
GLY A3078
 None
 0.98A 3hcrB-3hwcA:
undetectable		 3hcrB-3hwcA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_A_ACTA901_0
(PYRANOSE 2-OXIDASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 5 GLN A3069
PHE A3043
HIS A3105
ASN A3106
 None
 1.39A 3lskA-3hwcA:
0.0		 3lskA-3hwcA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 6 GLN A3069
PHE A3043
HIS A3105
ASN A3106
 None
 1.37A 3lskB-3hwcA:
undetectable		 3lskB-3hwcA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_C_ACTC901_0
(PYRANOSE 2-OXIDASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 5 GLN A3069
PHE A3043
HIS A3105
ASN A3106
 None
 1.41A 3lskC-3hwcA:
0.0		 3lskC-3hwcA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 6 GLN A3069
PHE A3043
HIS A3105
ASN A3106
 None
 1.36A 3lskD-3hwcA:
undetectable		 3lskD-3hwcA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_A_ZMRA1002_2
(NEURAMINIDASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 5 LEU A3430
ARG A3428
ILE A3391
ARG A3425
 None
 1.23A 3ticA-3hwcA:
undetectable		 3ticA-3hwcA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		3 / 3 PHE A3109
CYH A3149
HIS A3201
 None
 1.01A 3u9fF-3hwcA:
undetectable		 3u9fF-3hwcA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		3 / 3 PHE A3109
CYH A3149
HIS A3201
 None
 1.07A 3u9fG-3hwcA:
undetectable		 3u9fG-3hwcA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		3 / 3 PHE A3109
CYH A3149
HIS A3201
 None
 1.02A 3u9fL-3hwcA:
undetectable		 3u9fL-3hwcA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZMD_A_SALA201_1
(PUTATIVE
TRANSCRIPTIONAL
REGULATOR)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ARG A3083
LEU A3298
ARG A3091
HIS A3333
 None
 1.18A 3zmdA-3hwcA:
undetectable
3zmdB-3hwcA:
undetectable		 3zmdA-3hwcA:
15.47
3zmdB-3hwcA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.14A 4feuF-3hwcA:
undetectable		 4feuF-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 7 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.20A 4fevB-3hwcA:
undetectable		 4fevB-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 7 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.12A 4fevD-3hwcA:
undetectable		 4fevD-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 7 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.14A 4fevF-3hwcA:
undetectable		 4fevF-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 7 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.21A 4fewB-3hwcA:
undetectable		 4fewB-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.13A 4fewD-3hwcA:
undetectable		 4fewD-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.15A 4fewF-3hwcA:
undetectable		 4fewF-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 7 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.14A 4fexB-3hwcA:
undetectable		 4fexB-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.12A 4gkhB-3hwcA:
undetectable		 4gkhB-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.19A 4gkhD-3hwcA:
undetectable		 4gkhD-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.11A 4gkhF-3hwcA:
undetectable		 4gkhF-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 7 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.14A 4gkhG-3hwcA:
undetectable		 4gkhG-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 6 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.19A 4gkhJ-3hwcA:
undetectable		 4gkhJ-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.15A 4gkhC-3hwcA:
undetectable
4gkhK-3hwcA:
undetectable		 4gkhC-3hwcA:
20.16
4gkhK-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.15A 4gkiA-3hwcA:
undetectable		 4gkiA-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3461
ASP A3286
ASN A3358
ASP A3363
 None
 1.15A 4gkiC-3hwcA:
undetectable		 4gkiC-3hwcA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3060
SER A3067
PHE A3058
ASP A3072
 None
 1.08A 4kttA-3hwcA:
undetectable		 4kttA-3hwcA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3060
SER A3067
PHE A3058
ASP A3072
 None
 1.08A 4kttC-3hwcA:
undetectable		 4kttC-3hwcA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		3 / 3 ARG A3418
ASP A3398
ARG A3425
 None
 0.87A 4mx0A-3hwcA:
undetectable		 4mx0A-3hwcA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		5 / 12 GLY A3004
ALA A3041
TYR A3036
LEU A3011
ASN A3106
 None
 1.17A 4pd5A-3hwcA:
undetectable		 4pd5A-3hwcA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XYZ_A_ACTA103_0
(POLYUBIQUITIN-C)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 4 LEU A3131
ILE A3271
HIS A3270
VAL A3268
 None
 1.07A 4xyzA-3hwcA:
undetectable		 4xyzA-3hwcA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_A_TRPA403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 THR A3224
PRO A3225
ILE A3263
PRO A3264
 None
 1.12A 6a4iA-3hwcA:
1.5		 6a4iA-3hwcA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		5 / 9 LEU A3383
SER A3387
GLY A3424
ILE A3423
ILE A3314
 None
 1.31A 6ebpA-3hwcA:
undetectable		 6ebpA-3hwcA:
9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3060
SER A3067
PHE A3058
ASP A3072
 None
 1.08A 6fboA-3hwcA:
undetectable		 6fboA-3hwcA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 8 ASP A3060
SER A3067
PHE A3058
ASP A3072
 None
 1.05A 6fcbA-3hwcA:
undetectable		 6fcbA-3hwcA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		3 / 3 LEU A3306
LEU A3430
ARG A3299
 None
 0.45A 6fgcA-3hwcA:
undetectable		 6fgcA-3hwcA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		3 / 3 LEU A3306
LEU A3430
ARG A3299
 None
 0.50A 6fgdA-3hwcA:
undetectable		 6fgdA-3hwcA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2
(Burkholderia
cepacia) 		4 / 7 ASP A3114
THR A3110
TYR A3112
HIS A3291
 None
 1.44A 6nmfN-3hwcA:
2.3
6nmfP-3hwcA:
1.5		 6nmfN-3hwcA:
21.31
6nmfP-3hwcA:
19.04