SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hxt'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FBM_B_RTLB951_0 (PROTEIN (CARTILAGE OLIGOMERIC MATRIX PROTEIN))	3hxt	5-FORMYLTETRAHYDROFO LATE CYCLO-LIGASE (Homo sapiens)	4 / 4	THR A 170 LEU A 171 LEU A  36 GLN A  32	None	1.19A	1fbmA-3hxtA: undetectable	1fbmA-3hxtA: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UKB_A_BEZA1301_0 (2-HYDROXY-6-OXO-7-ME THYLOCTA-2,4-DIENOAT E HYDROLASE)	3hxt	5-FORMYLTETRAHYDROFO LATE CYCLO-LIGASE (Homo sapiens)	4 / 6	ARG A  20 LEU A 146 PHE A 139 LEU A  13	None	1.01A	1ukbA-3hxtA: undetectable	1ukbA-3hxtA: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NV4_B_SAMB202_0 (UPF0066 PROTEIN AF_0241)	3hxt	5-FORMYLTETRAHYDROFO LATE CYCLO-LIGASE (Homo sapiens)	5 / 12	GLN A 182 PRO A 184 GLY A 138 LEU A 137 LEU A 181	None None None None MG  A 214 (-4.6A)	1.32A	2nv4B-3hxtA: undetectable	2nv4B-3hxtA: 21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4N_A_TPVA300_1 (PROTEASE)	3hxt	5-FORMYLTETRAHYDROFO LATE CYCLO-LIGASE (Homo sapiens)	5 / 12	LEU A 171 ILE A  54 ILE A  68 ILE A  41 LEU A 131	None	0.87A	2o4nA-3hxtA: undetectable	2o4nA-3hxtA: 17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A2Q_A_ACAA601_1 (6-AMINOHEXANOATE-CYC LIC-DIMER HYDROLASE)	3hxt	5-FORMYLTETRAHYDROFO LATE CYCLO-LIGASE (Homo sapiens)	4 / 7	GLY A 138 ALA A 172 ALA A 174 VAL A 192	None	0.72A	3a2qA-3hxtA: undetectable	3a2qA-3hxtA: 17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A35_A_RBFA191_1 (LUMAZINE PROTEIN)	3hxt	5-FORMYLTETRAHYDROFO LATE CYCLO-LIGASE (Homo sapiens)	5 / 12	VAL A 192 LEU A 171 THR A 170 THR A  64 ILE A  62	None	1.16A	3a35A-3hxtA: undetectable	3a35A-3hxtA: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A35_B_RBFB191_1 (LUMAZINE PROTEIN)	3hxt	5-FORMYLTETRAHYDROFO LATE CYCLO-LIGASE (Homo sapiens)	5 / 12	VAL A 192 LEU A 171 THR A 170 THR A  64 ILE A  62	None	1.12A	3a35B-3hxtA: undetectable	3a35B-3hxtA: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A3B_A_RBFA191_1 (LUMAZINE PROTEIN)	3hxt	5-FORMYLTETRAHYDROFO LATE CYCLO-LIGASE (Homo sapiens)	5 / 12	VAL A 192 LEU A 171 THR A 170 THR A  64 ILE A  62	None	1.12A	3a3bA-3hxtA: undetectable	3a3bA-3hxtA: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KIC_A_SAMA401_0 (METHYLTRANSFERASE MPPJ)	3hxt	5-FORMYLTETRAHYDROFO LATE CYCLO-LIGASE (Homo sapiens)	5 / 12	GLY A 138 GLY A 136 ARG A  14 ALA A 172 ASP A 140	None	1.03A	4kicA-3hxtA: 3.6	4kicA-3hxtA: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KIC_A_SAMA401_0 (METHYLTRANSFERASE MPPJ)	3hxt	5-FORMYLTETRAHYDROFO LATE CYCLO-LIGASE (Homo sapiens)	5 / 12	GLY A 138 GLY A 136 ARG A  14 ILE A 179 ASP A 140	None	1.18A	4kicA-3hxtA: 3.6	4kicA-3hxtA: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WG0_C_CHDC102_0 (NUCLEAR RECEPTOR COACTIVATOR 2)	3hxt	5-FORMYLTETRAHYDROFO LATE CYCLO-LIGASE (Homo sapiens)	4 / 7	LYS A  10 LEU A  13 LEU A 146 ARG A 145	None None None NI  A 209 (-3.2A)	0.76A	4wg0B-3hxtA: undetectable 4wg0C-3hxtA: undetectable	4wg0B-3hxtA: 5.67 4wg0C-3hxtA: 5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YVP_A_GBMA402_1 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C1)	3hxt	5-FORMYLTETRAHYDROFO LATE CYCLO-LIGASE (Homo sapiens)	5 / 11	LEU A 131 TYR A 169 ILE A  54 LEU A 196 LEU A 173	None	1.44A	4yvpA-3hxtA: undetectable	4yvpA-3hxtA: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD4_A_STIA604_1 (TYROSINE-PROTEIN KINASE ABL1)	3hxt	5-FORMYLTETRAHYDROFO LATE CYCLO-LIGASE (Homo sapiens)	4 / 5	TYR A 156 VAL A 195 PHE A  79 GLY A 128	NI  A 204 (-4.8A) None None None	1.19A	6hd4A-3hxtA: undetectable	6hd4A-3hxtA: 15.87