SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hyk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3hyk HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Bacillus
anthracis) 		4 / 6 ARG A  53
ILE A 101
GLY A  52
HIS A 103
 A3P  A 124 (-3.3A)
A3P  A 124 (-3.8A)
None
MG  A 120 ( 3.3A)
 0.97A 1wmqA-3hykA:
undetectable		 1wmqA-3hykA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3hyk HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Bacillus
anthracis) 		4 / 6 ARG A  53
ILE A 101
GLY A  52
HIS A 103
 A3P  A 124 (-3.3A)
A3P  A 124 (-3.8A)
None
MG  A 120 ( 3.3A)
 0.98A 1wmqB-3hykA:
undetectable		 1wmqB-3hykA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3hyk HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Bacillus
anthracis) 		4 / 6 ARG A  53
ILE A 101
GLY A  52
HIS A 103
 A3P  A 124 (-3.3A)
A3P  A 124 (-3.8A)
None
MG  A 120 ( 3.3A)
 0.95A 1wpuA-3hykA:
undetectable		 1wpuA-3hykA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3hyk HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Bacillus
anthracis) 		4 / 6 ARG A  53
ILE A 101
GLY A  52
HIS A 103
 A3P  A 124 (-3.3A)
A3P  A 124 (-3.8A)
None
MG  A 120 ( 3.3A)
 0.96A 1wpuB-3hykA:
undetectable		 1wpuB-3hykA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3hyk HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Bacillus
anthracis) 		4 / 6 ARG A  53
ILE A 101
GLY A  52
HIS A 103
 A3P  A 124 (-3.3A)
A3P  A 124 (-3.8A)
None
MG  A 120 ( 3.3A)
 0.95A 1wrqA-3hykA:
undetectable		 1wrqA-3hykA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3hyk HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Bacillus
anthracis) 		4 / 6 ARG A  53
ILE A 101
GLY A  52
HIS A 103
 A3P  A 124 (-3.3A)
A3P  A 124 (-3.8A)
None
MG  A 120 ( 3.3A)
 0.95A 1wrqB-3hykA:
undetectable		 1wrqB-3hykA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 3hyk HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Bacillus
anthracis) 		4 / 5 LEU A 114
ALA A  59
VAL A  72
ILE A  68
 None
None
None
CL  A 122 (-4.4A)
 0.98A 4xe3A-3hykA:
undetectable		 4xe3A-3hykA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 3hyk HOLO-[ACYL-CARRIER-P
ROTEIN] SYNTHASE
(Bacillus
anthracis) 		5 / 12 ILE A  77
LEU A  89
GLY A  65
ALA A  63
LEU A 114
 None
 1.23A 5zwrA-3hykA:
undetectable		 5zwrA-3hykA:
14.18