SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hz2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1000_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		4 / 6 GLU A   4
LYS A  41
PRO A  62
LYS A   1
 None
 1.43A 4a7tA-3hz2A:
undetectable		 4a7tA-3hz2A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 ASN A  12
SER A  66
SER A  67
 None
 0.71A 5gsnA-3hz2A:
undetectable		 5gsnA-3hz2A:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.72A 5qguA-3hz2A:
undetectable		 5qguA-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.67A 5qgvA-3hz2A:
undetectable		 5qgvA-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.65A 5qgwA-3hz2A:
undetectable		 5qgwA-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.66A 5qgxA-3hz2A:
undetectable		 5qgxA-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.67A 5qgyA-3hz2A:
undetectable		 5qgyA-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.65A 5qgzA-3hz2A:
undetectable		 5qgzA-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.67A 5qh0A-3hz2A:
undetectable		 5qh0A-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.67A 5qh1A-3hz2A:
undetectable		 5qh1A-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.65A 5qh2A-3hz2A:
undetectable		 5qh2A-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.66A 5qh3A-3hz2A:
undetectable		 5qh3A-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.70A 5qh4A-3hz2A:
undetectable		 5qh4A-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.65A 5qh6A-3hz2A:
undetectable		 5qh6A-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.68A 5qh9A-3hz2A:
undetectable		 5qh9A-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.65A 5qhaA-3hz2A:
undetectable		 5qhaA-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.72A 5qhcA-3hz2A:
undetectable		 5qhcA-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.72A 5qheA-3hz2A:
undetectable		 5qheA-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.66A 5qhfA-3hz2A:
undetectable		 5qhfA-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 VAL A  40
VAL A   5
GLN A  83
 None
 0.68A 5qhhA-3hz2A:
undetectable		 5qhhA-3hz2A:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hz2 BETA/GAMA CRYSTALLIN
FAMILY PROTEIN
(Methanosarcina
acetivorans) 		3 / 3 GLN A  83
TRP A  45
VAL A  40
 None
 1.16A 6auuA-3hz2A:
undetectable		 6auuA-3hz2A:
11.89