SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hz6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 12 VAL A 301
ILE A 307
ALA A 385
SER A 388
LEU A 389
 None
 1.00A 1cqeA-3hz6A:
undetectable		 1cqeA-3hz6A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 12 VAL A 301
ILE A 307
ALA A 385
SER A 388
LEU A 389
 None
 0.99A 1cqeB-3hz6A:
undetectable		 1cqeB-3hz6A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 9 VAL A 301
ILE A 307
ALA A 385
SER A 388
LEU A 389
 None
 0.99A 1eqgA-3hz6A:
undetectable		 1eqgA-3hz6A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 11 VAL A 301
ILE A 307
ALA A 385
SER A 388
LEU A 389
 None
 0.97A 1eqgB-3hz6A:
undetectable		 1eqgB-3hz6A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_A_FLPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 12 VAL A 301
ILE A 307
ALA A 385
SER A 388
LEU A 389
 None
 1.01A 1eqhA-3hz6A:
undetectable		 1eqhA-3hz6A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 12 VAL A 301
ILE A 307
ALA A 385
SER A 388
LEU A 389
 None
 1.01A 1eqhB-3hz6A:
undetectable		 1eqhB-3hz6A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 4 LEU A  85
PRO A  86
LEU A  87
ARG A 166
 None
 1.39A 1hrkB-3hz6A:
undetectable		 1hrkB-3hz6A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 12 TYR A 100
GLY A  11
THR A  12
LEU A 287
ALA A 245
 GOL  A 513 (-3.4A)
None
GOL  A 513 (-4.1A)
None
None
 1.38A 1jipA-3hz6A:
undetectable		 1jipA-3hz6A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		3 / 3 ASP A 479
LYS A 486
ARG A 489
 None
 1.20A 1ra8A-3hz6A:
undetectable		 1ra8A-3hz6A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 12 LEU A 439
LEU A 442
LEU A 445
ALA A 446
LEU A 236
 None
 0.91A 1s9pC-3hz6A:
undetectable		 1s9pC-3hz6A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 4 THR A 181
GLY A 240
ASP A 241
ALA A 159
 None
None
GOL  A 513 (-2.7A)
None
 1.27A 1sg9A-3hz6A:
undetectable		 1sg9A-3hz6A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 4 LEU A 196
PRO A 128
ILE A 134
LEU A 135
 None
 0.98A 1ya4C-3hz6A:
undetectable		 1ya4C-3hz6A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		3 / 3 THR A 283
PRO A 355
PRO A 300
 None
None
XUL  A 515 (-4.2A)
 0.82A 2d55C-3hz6A:
undetectable		 2d55C-3hz6A:
2.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 4 LEU A  85
PRO A  86
LEU A  87
ARG A 166
 None
 1.40A 2hrcB-3hz6A:
undetectable		 2hrcB-3hz6A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 4 LEU A  85
PRO A  86
LEU A  87
ARG A 166
 None
 1.41A 2pnjB-3hz6A:
undetectable		 2pnjB-3hz6A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA426_0
(FERROCHELATASE)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 4 LEU A  85
PRO A  86
LEU A  87
ARG A 166
 None
 1.46A 2qd2A-3hz6A:
undetectable		 2qd2A-3hz6A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 8 LEU A 450
ILE A   5
ARG A  22
GLY A  24
 None
 0.96A 3b9lA-3hz6A:
undetectable		 3b9lA-3hz6A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 10 ILE A 307
GLY A 384
LEU A 387
PRO A 355
VAL A 356
 None
 1.01A 3em4V-3hz6A:
undetectable		 3em4V-3hz6A:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_B_GJZB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 6 PHE A   8
ILE A  58
ALA A  59
ALA A  69
 None
 1.07A 3mdrB-3hz6A:
undetectable		 3mdrB-3hz6A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 12 ILE A 307
GLY A 384
ALA A 385
SER A 388
LEU A 389
 None
 1.17A 3n8xA-3hz6A:
undetectable		 3n8xA-3hz6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 12 ILE A 307
GLY A 384
ALA A 385
SER A 388
LEU A 389
 None
 1.00A 3n8xB-3hz6A:
undetectable		 3n8xB-3hz6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		6 / 11 VAL A 301
ILE A 307
GLY A 384
ALA A 385
SER A 388
LEU A 389
 None
 1.41A 3n8yA-3hz6A:
0.3		 3n8yA-3hz6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 12 VAL A 301
ILE A 307
ALA A 385
SER A 388
LEU A 389
 None
 1.02A 3n8zB-3hz6A:
undetectable		 3n8zB-3hz6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_2
(GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 9 PRO A 105
ALA A 132
GLN A  82
PHE A  84
PHE A 285
 None
None
XUL  A 515 (-3.9A)
None
XUL  A 515 (-3.3A)
 1.26A 3qelD-3hz6A:
undetectable		 3qelD-3hz6A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QJ7_A_SPMA264_1
(THYMIDYLATE SYNTHASE)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 8 ALA A 223
GLN A 226
LEU A 167
TYR A  52
 None
 0.80A 3qj7A-3hz6A:
undetectable
3qj7D-3hz6A:
undetectable		 3qj7A-3hz6A:
20.51
3qj7D-3hz6A:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 4 LEU A 343
GLY A 342
GLY A 367
THR A 369
 None
PO4  A 511 (-3.5A)
PO4  A 511 ( 4.1A)
None
 0.64A 3si7A-3hz6A:
undetectable		 3si7A-3hz6A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 5 LEU A 343
GLY A 342
GLY A 367
THR A 369
 None
PO4  A 511 (-3.5A)
PO4  A 511 ( 4.1A)
None
 0.64A 3si7C-3hz6A:
undetectable
3si7D-3hz6A:
undetectable		 3si7C-3hz6A:
20.08
3si7D-3hz6A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 12 GLY A 158
ASP A 174
GLY A  11
ALA A 244
ALA A 245
 None
 1.22A 3sueB-3hz6A:
undetectable		 3sueB-3hz6A:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_B_IMNB701_1
(CYCLOOXYGENASE-2)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 12 VAL A 301
TYR A 348
ALA A 385
SER A 388
LEU A 389
 None
 1.14A 4coxB-3hz6A:
undetectable		 4coxB-3hz6A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COX_D_IMND701_1
(CYCLOOXYGENASE-2)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 12 VAL A 301
TYR A 348
ALA A 385
SER A 388
LEU A 389
 None
 1.15A 4coxD-3hz6A:
undetectable		 4coxD-3hz6A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_3
(HIV-1 PROTEASE)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		3 / 3 ASP A 174
LEU A 445
VAL A 251
 None
 0.69A 4jecB-3hz6A:
undetectable		 4jecB-3hz6A:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 5 GLN A 215
THR A 233
THR A   7
LEU A 450
 None
 1.05A 4lvcB-3hz6A:
undetectable		 4lvcB-3hz6A:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 11 ILE A 112
ALA A 114
LEU A 121
ALA A 118
VAL A 139
 None
 1.07A 4nqaA-3hz6A:
undetectable		 4nqaA-3hz6A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 7 THR A  12
GLY A  11
THR A  13
HIS A 260
 GOL  A 513 (-4.1A)
None
None
None
 0.78A 4qwpB-3hz6A:
undetectable		 4qwpB-3hz6A:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		6 / 12 GLY A  79
GLY A  11
SER A  78
LEU A 239
ASP A 174
ALA A 245
 None
 1.47A 4uckB-3hz6A:
undetectable		 4uckB-3hz6A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 8 ARG A 461
VAL A 251
ASP A 253
ASP A 256
 None
 0.95A 4xqgA-3hz6A:
undetectable		 4xqgA-3hz6A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 8 ARG A 461
VAL A 251
ASP A 253
ASP A 256
 None
 0.94A 4xqgB-3hz6A:
undetectable		 4xqgB-3hz6A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 12 GLY A 240
LEU A 247
THR A 176
GLY A 289
ILE A 290
 None
 0.97A 5d4uD-3hz6A:
undetectable		 5d4uD-3hz6A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 11 ALA A 268
ALA A 257
VAL A 401
LEU A 404
LEU A 389
 None
 1.32A 5eb5A-3hz6A:
undetectable		 5eb5A-3hz6A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 12 VAL A 339
LEU A 379
ALA A 330
VAL A 381
GLY A 384
 None
 0.95A 5kirA-3hz6A:
undetectable		 5kirA-3hz6A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		3 / 3 TRP A 416
MET A 419
ASN A 423
 None
 1.32A 5uc1B-3hz6A:
undetectable		 5uc1B-3hz6A:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_SALA601_1
(SALICYLATE-AMP
LIGASE)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		5 / 9 PHE A 490
CYH A 493
GLY A 384
VAL A 346
LEU A 366
 None
PO4  A 511 ( 4.0A)
None
None
PO4  A 511 (-3.8A)
 1.19A 5wm2A-3hz6A:
0.0		 5wm2A-3hz6A:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6APH_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 5 GLN A 215
THR A 233
THR A   7
LEU A 450
 None
 1.00A 6aphA-3hz6A:
undetectable		 6aphA-3hz6A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_A_ADNA502_2
(-)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 4 GLN A 215
THR A 233
THR A   7
LEU A 450
 None
 0.98A 6f3mA-3hz6A:
undetectable		 6f3mA-3hz6A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_C_ADNC502_2
(-)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 4 GLN A 215
THR A 233
THR A   7
LEU A 450
 None
 0.97A 6f3mC-3hz6A:
undetectable		 6f3mC-3hz6A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_B_ADNB501_2
(-)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 5 GLN A 215
THR A 233
THR A   7
LEU A 450
 None
 1.05A 6gbnB-3hz6A:
undetectable		 6gbnB-3hz6A:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 8 ASP A   9
ILE A  10
TRP A  51
TYR A 100
 None
None
None
GOL  A 513 (-3.4A)
 1.22A 6hisA-3hz6A:
undetectable
6hisB-3hz6A:
undetectable		 6hisA-3hz6A:
12.04
6hisB-3hz6A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 8 ASP A   9
ILE A  10
TRP A  51
TYR A 100
 None
None
None
GOL  A 513 (-3.4A)
 1.23A 6hisB-3hz6A:
undetectable
6hisC-3hz6A:
undetectable		 6hisB-3hz6A:
12.04
6hisC-3hz6A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 8 ASP A   9
ILE A  10
TRP A  51
TYR A 100
 None
None
None
GOL  A 513 (-3.4A)
 1.22A 6hisC-3hz6A:
undetectable
6hisD-3hz6A:
undetectable		 6hisC-3hz6A:
12.04
6hisD-3hz6A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 8 ASP A   9
ILE A  10
TRP A  51
TYR A 100
 None
None
None
GOL  A 513 (-3.4A)
 1.23A 6hisD-3hz6A:
undetectable
6hisE-3hz6A:
undetectable		 6hisD-3hz6A:
12.04
6hisE-3hz6A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 3hz6 XYLULOKINASE
(Chromobacterium
violaceum) 		4 / 8 TYR A 100
ASP A   9
ILE A  10
TRP A  51
 GOL  A 513 (-3.4A)
None
None
None
 1.22A 6hisA-3hz6A:
undetectable
6hisE-3hz6A:
undetectable		 6hisA-3hz6A:
12.04
6hisE-3hz6A:
12.04