SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hzb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 3hzb CARBOHYDRATE BINDING
PROTEIN
(Flavobacterium
johnsoniae) 		5 / 12 VAL A  33
LEU A  31
LEU A  18
ALA A  49
ILE A  38
 None
 0.98A 1fk6A-3hzbA:
undetectable		 1fk6A-3hzbA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3hzb CARBOHYDRATE BINDING
PROTEIN
(Flavobacterium
johnsoniae) 		3 / 3 ARG A  83
GLY A  21
SER A  30
 None
 0.57A 2xctB-3hzbA:
undetectable		 2xctB-3hzbA:
8.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 3hzb CARBOHYDRATE BINDING
PROTEIN
(Flavobacterium
johnsoniae) 		4 / 8 ILE A  82
LEU A  18
LYS A   7
GLY A  32
 None
 0.97A 3selX-3hzbA:
undetectable		 3selX-3hzbA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 3hzb CARBOHYDRATE BINDING
PROTEIN
(Flavobacterium
johnsoniae) 		4 / 6 ILE A  82
LEU A  18
LYS A   7
GLY A  32
 None
 1.01A 3sj1X-3hzbA:
undetectable		 3sj1X-3hzbA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 3hzb CARBOHYDRATE BINDING
PROTEIN
(Flavobacterium
johnsoniae) 		4 / 7 ILE A  82
LEU A  18
LYS A   7
GLY A  32
 None
 1.03A 4hajA-3hzbA:
undetectable		 4hajA-3hzbA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_1
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3hzb CARBOHYDRATE BINDING
PROTEIN
(Flavobacterium
johnsoniae) 		3 / 3 LYS A   7
ASN A  68
ASP A  37
 None
None
CA  A 101 (-4.5A)
 0.90A 4o1eA-3hzbA:
undetectable		 4o1eA-3hzbA:
16.38