SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i09'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_D_DCFD1853_2
(ADENOSINE DEAMINASE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 4 HIS A 200
LEU A 222
LEU A 249
LEU A 262
 None
 1.24A 1a4lD-3i09A:
undetectable		 1a4lD-3i09A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 4 ARG A  87
ALA A  86
ALA A 114
GLU A 116
 None
 1.12A 1e7bA-3i09A:
undetectable		 1e7bA-3i09A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 4 ARG A  87
ALA A  86
ALA A 114
GLU A 116
 None
 1.12A 1e7bB-3i09A:
undetectable		 1e7bB-3i09A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 5 ARG A  87
ALA A  86
ALA A 114
GLU A 116
 None
 1.19A 1e7cA-3i09A:
undetectable		 1e7cA-3i09A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		5 / 12 ALA A 126
GLY A 101
ASP A 349
GLY A 350
ARG A 347
 AAE  A 501 (-3.7A)
None
None
None
None
 0.97A 1sqfA-3i09A:
2.5		 1sqfA-3i09A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 8 TYR A 145
SER A 104
TYR A 121
HIS A 142
 None
AAE  A 501 (-2.5A)
None
None
 1.25A 2bteA-3i09A:
undetectable		 2bteA-3i09A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 8 TYR A 145
SER A 104
TYR A 121
HIS A 142
 None
AAE  A 501 (-2.5A)
None
None
 1.25A 2bteD-3i09A:
undetectable		 2bteD-3i09A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OC8_A_HU5A999_1
(HEPATITIS C VIRUS)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		5 / 12 HIS A 200
LEU A 253
GLY A 228
PHE A 175
ALA A 225
 None
None
EDO  A   8 ( 4.0A)
AAE  A 501 (-3.6A)
None
 1.00A 2oc8A-3i09A:
undetectable		 2oc8A-3i09A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_A_BEZA143_0
(PUTATIVE REDOX
PROTEIN)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 7 ALA A 107
THR A 106
ALA A 105
TYR A  40
 None
None
None
AAE  A 501 ( 4.0A)
 0.94A 2ql8A-3i09A:
undetectable
2ql8B-3i09A:
undetectable		 2ql8A-3i09A:
15.92
2ql8B-3i09A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0G_A_LEUA1887_0
(AMINOACYL-TRNA
SYNTHETASE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 8 TYR A 145
SER A 104
TYR A 121
HIS A 142
 None
AAE  A 501 (-2.5A)
None
None
 1.29A 2v0gA-3i09A:
undetectable		 2v0gA-3i09A:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 8 LEU A  97
TRP A 287
THR A 311
TRP A 276
 None
 1.07A 2y69C-3i09A:
undetectable
2y69N-3i09A:
undetectable
2y69P-3i09A:
undetectable		 2y69C-3i09A:
22.07
2y69N-3i09A:
21.43
2y69P-3i09A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 8 LEU A  97
TRP A 287
THR A 311
TRP A 276
 None
 1.07A 3ablC-3i09A:
undetectable
3ablN-3i09A:
undetectable
3ablP-3i09A:
undetectable		 3ablC-3i09A:
22.07
3ablN-3i09A:
21.43
3ablP-3i09A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		5 / 9 ILE A 122
GLY A 100
ILE A  33
VAL A  70
ILE A  52
 None
None
None
EDO  A  12 (-4.0A)
None
 1.30A 3ekyB-3i09A:
undetectable		 3ekyB-3i09A:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 7 TYR A 173
ASN A 123
HIS A 142
ALA A 128
 AAE  A 501 (-4.5A)
None
None
None
 1.23A 3frqB-3i09A:
undetectable		 3frqB-3i09A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		5 / 12 GLY A 153
VAL A 158
VAL A 159
ALA A 149
LEU A 252
 None
 1.01A 3ku1H-3i09A:
2.3		 3ku1H-3i09A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		3 / 3 TYR A  40
GLY A 228
ASP A 258
 AAE  A 501 ( 4.0A)
EDO  A   8 ( 4.0A)
EDO  A   8 (-3.3A)
 0.70A 3ou6C-3i09A:
2.4		 3ou6C-3i09A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		5 / 12 HIS A 200
LEU A 253
GLY A 228
PHE A 175
ALA A 225
 None
None
EDO  A   8 ( 4.0A)
AAE  A 501 (-3.6A)
None
 1.02A 3sufA-3i09A:
undetectable		 3sufA-3i09A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		5 / 11 THR A 154
LEU A 270
THR A 267
LEU A 252
THR A 231
 None
 1.39A 3tbgA-3i09A:
undetectable		 3tbgA-3i09A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC2_1
(CYTOCHROME P450 2D6)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		5 / 10 THR A 154
LEU A 270
THR A 267
LEU A 252
THR A 231
 None
 1.37A 3tbgC-3i09A:
undetectable		 3tbgC-3i09A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 4 SER A 275
ASP A 339
ASP A  58
ALA A 304
 None
 1.27A 3uj6A-3i09A:
undetectable		 3uj6A-3i09A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		5 / 12 PHE A 168
GLY A 196
ALA A 178
GLY A 176
ASN A 182
 None
 1.18A 3v3oB-3i09A:
undetectable		 3v3oB-3i09A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 8 LEU A  97
TRP A 287
THR A 311
TRP A 276
 None
 1.09A 3x2qC-3i09A:
undetectable
3x2qN-3i09A:
undetectable
3x2qP-3i09A:
undetectable		 3x2qC-3i09A:
22.07
3x2qN-3i09A:
21.43
3x2qP-3i09A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_C_ACTC1113_0
(BLR5658 PROTEIN)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 4 ASN A 123
ALA A 107
GLY A 101
THR A 102
 None
None
None
AAE  A 501 (-4.0A)
 1.19A 4bboC-3i09A:
undetectable		 4bboC-3i09A:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		5 / 9 THR A 154
LEU A 224
LEU A 252
GLY A 223
VAL A 158
 None
 1.48A 4c9kB-3i09A:
undetectable		 4c9kB-3i09A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 7 GLY A  48
GLY A  47
MET A 295
TYR A 291
 None
 1.05A 4fgkB-3i09A:
undetectable		 4fgkB-3i09A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		6 / 12 GLY A  45
ILE A 124
GLY A 100
ILE A  33
VAL A  70
ILE A  52
 None
None
None
None
EDO  A  12 (-4.0A)
None
 1.41A 4jecA-3i09A:
undetectable		 4jecA-3i09A:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		3 / 3 LYS A 363
PRO A 364
SER A 365
 None
 0.38A 4k50I-3i09A:
undetectable		 4k50I-3i09A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M83_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		5 / 11 ASN A  77
ASN A 123
LEU A 131
ALA A  83
SER A 109
 None
 1.49A 4m83A-3i09A:
undetectable		 4m83A-3i09A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 8 LEU A  49
GLY A  47
GLU A  50
ALA A 305
 None
 0.89A 4rjdA-3i09A:
undetectable
4rjdB-3i09A:
undetectable		 4rjdA-3i09A:
9.95
4rjdB-3i09A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		5 / 12 GLY A 100
ASP A  44
PHE A 255
ILE A 124
ALA A 144
 None
 1.25A 4wh5A-3i09A:
undetectable		 4wh5A-3i09A:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 6 ASP A  74
ALA A  41
THR A  34
THR A 102
 None
None
None
AAE  A 501 (-4.0A)
 1.38A 4z4cA-3i09A:
4.9		 4z4cA-3i09A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 5 ASP A  74
ALA A  41
THR A  34
THR A 102
 None
None
None
AAE  A 501 (-4.0A)
 1.37A 4z4gA-3i09A:
4.8		 4z4gA-3i09A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 6 ASP A  74
ALA A  41
THR A  34
THR A 102
 None
None
None
AAE  A 501 (-4.0A)
 1.33A 4z4iA-3i09A:
5.0		 4z4iA-3i09A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		3 / 3 THR A 311
SER A 308
TYR A 307
 None
 0.82A 5jsdA-3i09A:
undetectable		 5jsdA-3i09A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		3 / 3 THR A 311
SER A 308
TYR A 307
 None
 0.84A 5jsdB-3i09A:
1.5		 5jsdB-3i09A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		3 / 3 THR A 311
SER A 308
TYR A 307
 None
 0.83A 5jsdC-3i09A:
1.6		 5jsdC-3i09A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		3 / 3 THR A 311
SER A 308
TYR A 307
 None
 0.83A 5jseA-3i09A:
undetectable		 5jseA-3i09A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		3 / 3 THR A 311
SER A 308
TYR A 307
 None
 0.83A 5jseB-3i09A:
undetectable		 5jseB-3i09A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		3 / 3 THR A 311
SER A 308
TYR A 307
 None
 0.84A 5jseC-3i09A:
undetectable		 5jseC-3i09A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 7 GLN A 303
TYR A 291
TRP A 371
ASP A  42
 None
None
EDO  A  11 (-4.5A)
EDO  A   8 (-4.4A)
 1.01A 5vlmE-3i09A:
undetectable		 5vlmE-3i09A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_1
(REGULATORY PROTEIN
TETR)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 7 GLN A 303
TYR A 291
TRP A 371
ASP A  42
 None
None
EDO  A  11 (-4.5A)
EDO  A   8 (-4.4A)
 1.13A 5vlmG-3i09A:
undetectable		 5vlmG-3i09A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 8 TRP A 287
THR A 311
TRP A 276
LEU A  97
 None
 1.01A 5w97A-3i09A:
undetectable
5w97C-3i09A:
undetectable
5w97c-3i09A:
undetectable		 5w97A-3i09A:
21.43
5w97C-3i09A:
22.07
5w97c-3i09A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 8 TRP A 287
THR A 311
TRP A 276
LEU A  97
 None
 1.06A 5x19A-3i09A:
undetectable
5x19C-3i09A:
undetectable
5x19P-3i09A:
undetectable		 5x19A-3i09A:
21.43
5x19C-3i09A:
22.07
5x19P-3i09A:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_0
(NS3 PROTEASE)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		5 / 12 HIS A 200
LEU A 253
GLY A 228
PHE A 175
ALA A 225
 None
None
EDO  A   8 ( 4.0A)
AAE  A 501 (-3.6A)
None
 1.03A 6c2mA-3i09A:
undetectable		 6c2mA-3i09A:
12.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3i09 PERIPLASMIC
BRANCHED-CHAIN AMINO
ACID-BINDING PROTEIN
(Burkholderia
mallei) 		4 / 8 LEU A  97
TRP A 287
THR A 311
TRP A 276
 None
 1.02A 6nknC-3i09A:
undetectable
6nknN-3i09A:
undetectable
6nknP-3i09A:
undetectable		 6nknC-3i09A:
22.07
6nknN-3i09A:
21.43
6nknP-3i09A:
22.07