SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i0z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		4 / 8 ASP A 297
TYR A 346
ARG A 342
THR A 293
 None
 0.98A 1ceaA-3i0zA:
undetectable
1ceaB-3i0zA:
undetectable		 1ceaA-3i0zA:
11.05
1ceaB-3i0zA:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		4 / 7 GLN A 166
THR A 187
SER A 183
TYR A  35
 None
 1.37A 1eiiA-3i0zA:
undetectable		 1eiiA-3i0zA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		4 / 7 PHE A 353
TYR A 234
LEU A 284
TYR A 349
 None
 1.25A 1rmtB-3i0zA:
undetectable		 1rmtB-3i0zA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		5 / 7 PHE A  88
TYR A  81
VAL A 191
VAL A 111
VAL A 113
 None
 1.39A 2qbnA-3i0zA:
undetectable		 2qbnA-3i0zA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		3 / 3 ASN A 171
ARG A 117
ASP A 366
 None
 0.91A 2qe6A-3i0zA:
2.0		 2qe6A-3i0zA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		3 / 3 ASN A 171
ARG A 117
ASP A 366
 None
 0.96A 2qe6B-3i0zA:
2.2		 2qe6B-3i0zA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_C_X2NC1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		5 / 12 PHE A 286
VAL A 207
ALA A 244
THR A  65
MET A 185
 None
 1.00A 2x2nC-3i0zA:
1.9		 2x2nC-3i0zA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		5 / 11 THR A 127
TYR A 103
ALA A  92
GLY A  62
ALA A  63
 None
None
None
None
PO4  A 390 ( 4.6A)
 1.33A 2xh9A-3i0zA:
undetectable		 2xh9A-3i0zA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		4 / 7 VAL A 374
ALA A 256
GLY A 372
THR A 373
 None
 0.77A 2xrzB-3i0zA:
undetectable		 2xrzB-3i0zA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		4 / 8 SER A 114
THR A 127
VAL A 128
LEU A 125
 None
 0.88A 3ax7A-3i0zA:
undetectable		 3ax7A-3i0zA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		3 / 3 ASN A 120
ASP A 148
ARG A  19
 None
 0.81A 3k13A-3i0zA:
undetectable		 3k13A-3i0zA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZW_A_KKKA413_1
(FLAVOHEMOGLOBIN)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		4 / 8 ILE A  21
GLN A 351
ALA A 354
LEU A 355
 None
 0.74A 3ozwA-3i0zA:
4.7		 3ozwA-3i0zA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		4 / 7 VAL A 304
LEU A 235
MET A 262
ILE A 233
 None
 0.99A 3rfmA-3i0zA:
undetectable		 3rfmA-3i0zA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		4 / 5 THR A 289
GLY A 287
GLU A 328
ASP A 318
 None
 0.69A 5c0oH-3i0zA:
2.7		 5c0oH-3i0zA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		5 / 11 VAL A 111
VAL A 141
VAL A 113
TRP A  86
LEU A  46
 None
 1.04A 5e4dB-3i0zA:
undetectable		 5e4dB-3i0zA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE
(Streptococcus
pneumoniae) 		4 / 7 THR A 110
LEU A 112
ILE A  91
THR A  61
 None
 1.01A 5zsfA-3i0zA:
undetectable
5zsfB-3i0zA:
undetectable		 5zsfA-3i0zA:
13.06
5zsfB-3i0zA:
13.06