SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3i10'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		5 / 11 VAL A 168
LEU A 145
ILE A 141
ALA A 137
LEU A 134
 None
 1.16A 1eqgB-3i10A:
undetectable		 1eqgB-3i10A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 SER A 242
PHE A 219
ALA A 217
PHE A  33
 None
 1.24A 1fxvA-3i10A:
undetectable
1fxvB-3i10A:
undetectable		 1fxvA-3i10A:
22.64
1fxvB-3i10A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A  73
ASN A 144
TRP A 245
 None
 1.05A 1r15C-3i10A:
undetectable		 1r15C-3i10A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A  73
ASN A 144
TRP A 245
 None
 1.06A 1r15D-3i10A:
undetectable		 1r15D-3i10A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A  73
ASN A 144
TRP A 245
 None
 1.07A 1r15E-3i10A:
undetectable		 1r15E-3i10A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A  73
ASN A 144
TRP A 245
 None
 1.05A 1r15F-3i10A:
undetectable		 1r15F-3i10A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_1
(PROTEASE)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 238
ILE A 222
PRO A 231
ILE A 234
ILE A 244
 None
EDO  A  17 (-4.5A)
None
None
None
 1.02A 3ebzA-3i10A:
undetectable		 3ebzA-3i10A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		5 / 9 LEU A 134
LEU A 145
ILE A  71
ILE A  29
GLN A 167
 None
None
None
EDO  A   6 ( 4.6A)
None
 1.35A 3tmzA-3i10A:
undetectable		 3tmzA-3i10A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		5 / 9 GLU A 220
ALA A 218
ILE A 281
VAL A  44
ILE A  71
 PEG  A  21 (-3.1A)
None
None
None
None
 1.05A 4lbgB-3i10A:
2.1		 4lbgB-3i10A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 VAL A  69
VAL A  43
GLN A 283
 None
None
PEG  A  21 ( 4.5A)
 0.71A 5qglA-3i10A:
undetectable		 5qglA-3i10A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 VAL A  69
VAL A  43
GLN A 283
 None
None
PEG  A  21 ( 4.5A)
 0.70A 5qgvA-3i10A:
undetectable		 5qgvA-3i10A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 VAL A  69
VAL A  43
GLN A 283
 None
None
PEG  A  21 ( 4.5A)
 0.70A 5qgwA-3i10A:
undetectable		 5qgwA-3i10A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 VAL A  69
VAL A  43
GLN A 283
 None
None
PEG  A  21 ( 4.5A)
 0.69A 5qgxA-3i10A:
undetectable		 5qgxA-3i10A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 VAL A  69
VAL A  43
GLN A 283
 None
None
PEG  A  21 ( 4.5A)
 0.71A 5qh1A-3i10A:
undetectable		 5qh1A-3i10A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 VAL A  69
VAL A  43
GLN A 283
 None
None
PEG  A  21 ( 4.5A)
 0.72A 5qh4A-3i10A:
undetectable		 5qh4A-3i10A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		3 / 3 VAL A  69
VAL A  43
GLN A 283
 None
None
PEG  A  21 ( 4.5A)
 0.70A 5qhfA-3i10A:
undetectable		 5qhfA-3i10A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3i10 PUTATIVE
GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ASP A 285
ARG A  47
GLU A  73
ASP A  75
 None
EDO  A  10 (-4.3A)
None
None
 1.36A 6mn5E-3i10A:
undetectable		 6mn5E-3i10A:
16.26